-
1.发明申请NOVEL TETRAHYDRONAPHALENE ANTAGONISTS TO THE THROMBOXANE A2 (TP) RECEPTOR 审中-公开对四氢叶酸A2（TP）受体的新的四氢萘酚拮抗剂
公开(公告)号：WO2012015944A2
公开(公告)日：2012-02-02
申请号：PCT/US2011045565
申请日：2011-07-27
Applicant: UNIV PENNSYLVANIA , TROJANOWSKI JOHN Q , LEE VIRGINIA M Y , BRUNDEN KURT R , SMITH AMOS B , HURYN DONNA M , BALLATORE CARLO , HOGAN ANNE-MARIE , PISCITELLI FRANCESCO
Inventor： TROJANOWSKI JOHN Q , LEE VIRGINIA M Y , BRUNDEN KURT R , SMITH AMOS B , HURYN DONNA M , BALLATORE CARLO , HOGAN ANNE-MARIE , PISCITELLI FRANCESCO
IPC: A61K31/18
CPC classification number: A61K31/18 , A61K31/196 , A61K31/216 , A61K31/357 , A61K31/41 , A61K31/4174 , A61K31/421 , A61K31/426 , A61K45/06 , C07C311/20 , C07D233/64 , C07D257/04 , C07D263/32 , C07D277/28 , C07D317/28
Abstract: The present invention relates to TP receptor antagonists, which have the ability to bind to TP receptor and optionally cross the blood brain barrier. The invention also provides compositions and methods for treating a disorder wherein activation of TP receptor is detrimental.
Abstract translation: 本发明涉及TP受体拮抗剂，其具有结合TP受体并任选地穿过血脑屏障的能力。 本发明还提供用于治疗其中TP受体活化是有害的病症的组合物和方法。
-
2.发明申请NOVEL TETRAHYDRONAPHTALENE ANTAGONISTS TO THE THROMBOXANE A2 (TP) RECEPTOR 审中-公开对四氢呋喃A2（TP）受体的新型四氢叶酸拮抗剂
公开(公告)号：WO2012015944A8
公开(公告)日：2012-06-07
申请号：PCT/US2011045565
申请日：2011-07-27
Applicant: UNIV PENNSYLVANIA , TROJANOWSKI JOHN Q , LEE VIRGINIA M Y , BRUNDEN KURT R , SMITH AMOS B , HURYN DONNA M , BALLATORE CARLO , HOGAN ANNE-MARIE , PISCITELLI FRANCESCO
Inventor： TROJANOWSKI JOHN Q , LEE VIRGINIA M Y , BRUNDEN KURT R , SMITH AMOS B , HURYN DONNA M , BALLATORE CARLO , HOGAN ANNE-MARIE , PISCITELLI FRANCESCO
IPC: A61K31/18
CPC classification number: A61K31/18 , A61K31/196 , A61K31/216 , A61K31/357 , A61K31/41 , A61K31/4174 , A61K31/421 , A61K31/426 , A61K45/06 , C07C311/20 , C07D233/64 , C07D257/04 , C07D263/32 , C07D277/28 , C07D317/28
Abstract: The present invention relates to TP receptor antagonists, which have the ability to bind to TP receptor and optionally cross the blood brain barrier. The invention also provides compositions and methods for treating a disorder wherein activation of TP receptor is detrimental.
Abstract translation: 本发明涉及TP受体拮抗剂，其具有结合TP受体并任选地穿过血脑屏障的能力。 本发明还提供用于治疗其中TP受体活化是有害的病症的组合物和方法。
-
Patent Agency Ranking
公开(公告)号：WO2012015944A3
公开(公告)日：2012-02-02
申请号：PCT/US2011/045565
申请日：2011-07-27
Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , TROJANOWSKI, John, Q. , LEE, Virginia, M.y. , BRUNDEN, Kurt, R. , SMITH, Amos, B. , HURYN, Donna, M. , BALLATORE, Carlo , HOGAN, Anne-marie , PISCITELLI, Francesco
Inventor： TROJANOWSKI, John, Q. , LEE, Virginia, M.y. , BRUNDEN, Kurt, R. , SMITH, Amos, B. , HURYN, Donna, M. , BALLATORE, Carlo , HOGAN, Anne-marie , PISCITELLI, Francesco
Abstract: The present invention relates to TP receptor antagonists, which have the ability to bind to TP receptor and optionally cross the blood brain barrier. The invention also provides compositions and methods for treating a disorder wherein activation of TP receptor is detrimental.
-
公开(公告)号：WO2011037985A8
公开(公告)日：2011-06-09
申请号：PCT/US2010049799
申请日：2010-09-22
Applicant: UNIV PENNSYLVANIA , US GOV HEALTH & HUMAN SERV , BALLATORE CARLO , BRUNDEN KURT R , CROWE ALEXANDER L , HURYN DONNA M , LEE VIRGINIA M Y , TROJANOWSKI JOHN Q , SMITH AMOS B , HUANG RUILI , HUANG WENWEI , JOHNSON RONALD L , PISCITELLI FRANCESCO
Inventor： BALLATORE CARLO , BRUNDEN KURT R , CROWE ALEXANDER L , HURYN DONNA M , LEE VIRGINIA M Y , TROJANOWSKI JOHN Q , SMITH AMOS B , HUANG RUILI , HUANG WENWEI , JOHNSON RONALD L , PISCITELLI FRANCESCO
CPC classification number: C07D495/04 , A61K31/5025 , A61K31/5377
Abstract: The present invention is directed to methods of inhibiting a tauopathy in a patient by administration of a compound of formula (I): Novel aminothienopyridazine compounds are also described.
Abstract translation: 本发明涉及通过给予式（I）化合物来抑制患者的tau蛋白病变的方法：还描述了新的氨基噻吩并哒嗪化合物。
-
公开(公告)号：WO2021016449A1
公开(公告)日：2021-01-28
申请号：PCT/US2020/043258
申请日：2020-07-23
Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , AXXAM S.P.A. , PEVARELLO, Paolo , RAY, William , HAMBY, Mary , LIGHTFOOT, Yaima Luzardo , JONES, Philip , THOMAS, Russell , LIBERATI, Chiara , TORINO, Domenica , CUSANO, Valentina , PISCITELLI, Francesco , YOUSIF, Ali , BOVOLENTA, Silvia
Inventor： PEVARELLO, Paolo , RAY, William , HAMBY, Mary , LIGHTFOOT, Yaima Luzardo , JONES, Philip , THOMAS, Russell , LIBERATI, Chiara , TORINO, Domenica , CUSANO, Valentina , PISCITELLI, Francesco , YOUSIF, Ali , BOVOLENTA, Silvia
IPC: C07D333/58
Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/ fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.
-
公开(公告)号：WO2011037985A1
公开(公告)日：2011-03-31
申请号：PCT/US2010/049799
申请日：2010-09-22
Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH A , BALLATORE, Carlo , BRUNDEN, Kurt, R. , CROWE, Alexander, L. , HURYN, Donna, M. , LEE, Virginia, M.Y. , TROJANOWSKI, John, Q. , SMITH, Amos, B. , HUANG, Ruili , HUANG, Wenwei , JOHNSON, Ronald, L. , PISCITELLI, Francesco
Inventor： BALLATORE, Carlo , BRUNDEN, Kurt, R. , CROWE, Alexander, L. , HURYN, Donna, M. , LEE, Virginia, M.Y. , TROJANOWSKI, John, Q. , SMITH, Amos, B. , HUANG, Ruili , HUANG, Wenwei , JOHNSON, Ronald, L. , PISCITELLI, Francesco
CPC classification number: C07D495/04 , A61K31/5025 , A61K31/5377
Abstract: The present invention is directed to methods of inhibiting a tauopathy in a patient by administration of a compound of formula (I): Novel aminothienopyridazine compounds are also described.
Abstract translation: 本发明涉及通过施用式（I）化合物抑制患者中的tau蛋白病的方法：还描述了新的氨基噻吩并哒嗪化合物。
-
公开(公告)号：WO1996000271A1
公开(公告)日：1996-01-04
申请号：PCT/EP1995002330
申请日：1995-06-16
Applicant: BASF ITALIA S.P.A. , RABACCHI, Silvana , SARTO, Virginio , PISCITELLI, Francesco
Inventor： BASF ITALIA S.P.A.
IPC: C10L01/00
CPC classification number: C10L1/003 , C10L1/14 , C10L1/1608 , C10L1/1616 , C10L1/1824 , C10L1/1832 , C10L1/1852 , C10L1/1855 , C10L1/1857 , C10L1/189 , C10L1/19 , C10L1/1905 , C10L1/204 , C10L1/205 , C10L1/2222 , C10L1/2225 , C10L1/223 , C10L1/224 , C10L1/226 , C10L1/232 , C10M171/007 , C10M2207/08 , C10M2215/08 , C10M2215/082 , C10M2215/28 , G01N33/2882
Abstract: The invention concerns the use of beta -dicarbonyl or aromatic ortho-hydroxycarbonyl compounds to mark hydrocarbons, as well as hydrocarbons containing beta -dicarbonyl or aromatic ortho-hydroxycarbonyl compounds as markers and a method of assaying beta -dicarbonyl or aromatic ortho-hydroxycarbonyl compounds in hydrocarbons.
Abstract translation: 用于标记烃使用β-Dicarbonyl-或芳族邻羟基羰基的化合物，含有β--Dicarbonyl-或芳族邻羟基羰基化合物作为标记试剂，以及用于检测的β-Dicarbonyl-或在烃类芳族邻羟基羰基化合物的方法的烃。
-
-
-
-
-
-
Search Results
7
records
(took 0.02 seconds)
