公开(公告)号：WO2013028334A3

公开(公告)日：2013-04-25

申请号：PCT/US2012049501

申请日：2012-08-03

Applicant: EMD MILLIPORE CORP ,  JABER JAD ,  MOYA WILSON ,  POTTY AJISH ,  DUPONT ALISON ,  STONE MATHEW ,  KOZLOV MIKHAEL

Inventor： JABER JAD ,  MOYA WILSON ,  POTTY AJISH ,  DUPONT ALISON ,  STONE MATHEW ,  KOZLOV MIKHAEL

IPC: A61K39/395 ,  A61P35/00

CPC classification number: C07K16/00 ,  B01D15/327 ,  B01D15/361 ,  B01D15/3804 ,  B01D15/3847 ,  C07K1/30

Abstract: The present invention relates to novel and improved methods for the purification of biomolecules. In particular, the present invention relates to methods of protein purification which employ small molecules, which include al least one non- polar group and at least one cationic group or which include at least one non-polar group and at least one anionic group.

Abstract translation: 本发明涉及用于纯化生物分子的新颖和改进的方法。 特别地，本发明涉及使用小分子的蛋白质纯化方法，所述小分子包含至少一个非极性基团和至少一个阳离子基团，或者包括至少一个非极性基团和至少一个阴离子基团。

公开(公告)号：WO2013028334A2

公开(公告)日：2013-02-28

申请号：PCT/US2012/049501

申请日：2012-08-03

Applicant: EMD MILLIPORE CORPORATION ,  JABER, Jad ,  MOYA, Wilson ,  POTTY, Ajish ,  DUPONT, Alison ,  STONE, Mathew ,  KOZLOV, Mikhael

Inventor： JABER, Jad ,  MOYA, Wilson ,  POTTY, Ajish ,  DUPONT, Alison ,  STONE, Mathew ,  KOZLOV, Mikhael

IPC: A61K39/395 ,  A61P35/00

CPC classification number: C07K16/00 ,  B01D15/327 ,  B01D15/361 ,  B01D15/3804 ,  B01D15/3847 ,  C07K1/30

Abstract: The present invention relates to novel and improved methods for the purification of biomolecules. In particular, the present invention relates to methods of protein purification which employ small molecules, which include al least one non- polar group and at least one cationic group or which include at least one non-polar group and at least one anionic group.

Abstract translation: 本发明涉及用于纯化生物分子的新颖和改进的方法。 特别地，本发明涉及使用包括至少一个非极性基团和至少一个阳离子基团或包括至少一个非极性基团和至少一个阴离子基团的小分子的蛋白质纯化方法。