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公开(公告)号:TWI516595B
公开(公告)日:2016-01-11
申请号:TW098131037
申请日:2009-09-15
Inventor: 卡彼爾 桑傑伊 , KAPIL, SANJAY , 庫柏 艾美莉 , COOPER, EMILY
IPC: C12N15/35 , A61K39/23 , G01N33/569
CPC classification number: A61K39/23 , A61K39/12 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N2750/14022 , C12N2750/14032 , C12N2750/14034 , C12N2750/14043 , C12N2750/14051 , C12N2750/14071 , C12N2750/14334 , C12Q1/701 , G01N33/56983 , G01N2333/015
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公开(公告)号:US12263156B2
公开(公告)日:2025-04-01
申请号:US17502975
申请日:2021-10-15
Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College , University of Kansas , The Board of Regents for Oklahoma State University
Inventor: Mario Rivera , Huili Yao , Richard A. Bunce , Baskar Nammalwar , Krishna Kumar Gnanasekaran , Kate Eshelman , Achala N. D. Punchi Hewage , Scott Lovell , Anabel Soldano
IPC: A61P31/04 , A61K31/4035
Abstract: The present invention discloses methods of inhibiting biofilm formation, increasing bacteriocidal activity within a biofilm, treating bacteria within a biofilm, or remediating a biofilm in or on a subject, comprising administering to the subject an effective amount of a compound according to Formula I: wherein R1-5 are defined herein.
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公开(公告)号:US12251370B2
公开(公告)日:2025-03-18
申请号:US17299267
申请日:2019-12-03
Applicant: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE , UNIVERSITY OF KANSAS , THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY
Inventor: Mario Rivera , Huili Yao , Richard A. Bunce , Baskar Nammalwar , Krishna Kumar Gnanasekaran , Kate Eshelman , Achala N. D. Punchi Hewage , Scott Lovell
IPC: A61K31/4035 , A61K31/454 , A61K31/496 , A61K31/502 , A61P31/04 , C07D209/48 , C07D237/32 , C07D401/12 , C07D405/12
Abstract: The present technology provides compounds of Formula I and related methods for treating a bacterial infection as well as methods for inhibiting interaction of a bacterioferritin and a bacterioferritin-associated ferredoxin.
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公开(公告)号:US11993573B2
公开(公告)日:2024-05-28
申请号:US17167251
申请日:2021-02-04
Inventor: Kenneth Darrell Berlin , Richard A. Bunce , Krishna Kumar Gnanasekaran , Field M. Watts, Jr. , Donghua Howard Zhou
IPC: A61P35/00 , A61K31/352 , A61K31/382 , A61K31/47 , C07D215/06 , C07D311/70 , C07D335/06
CPC classification number: C07D215/06 , A61K31/352 , A61K31/382 , A61K31/47 , A61P35/00 , C07D311/70 , C07D335/06
Abstract: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.
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公开(公告)号:US20230136602A1
公开(公告)日:2023-05-04
申请号:US17938851
申请日:2022-10-07
Inventor: WENDY L. PICKING , WILLIAM D. PICKING
IPC: A61K39/112 , A61K39/00
Abstract: Antigenic molecules and compositions described herein protect against infection by typhoidal and non-typhoidal Salmonella serovars. Methods of immunization comprise the use of the antigenic molecules.
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公开(公告)号:US11370878B2
公开(公告)日:2022-06-28
申请号:US17019920
申请日:2020-09-14
Inventor: Toby Larue Nelson
IPC: C07D209/04 , C08G61/12 , C07D209/24 , C08G73/06 , C09D179/04 , C07D209/42 , C09D5/24 , C09D165/00 , H01L51/00 , C08K3/04 , H01L51/05 , H01L51/42 , H01L51/50
Abstract: “Black” photoactive materials that comprise synthetic eumelanin polymers are provided, as are methods of making and using the polymers. The synthetic eumelanin polymers are made from the plant oil vanillin, and exhibit defined structural and chemical characteristics (e.g. homogeneity, solubility, etc.) that make them suitable for use in devices that require photoactive materials, such as solar cells.
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公开(公告)号:US11234600B2
公开(公告)日:2022-02-01
申请号:US16035282
申请日:2018-07-13
Inventor: Daqing Piao
Abstract: This invention is regarding a set of stand-alone or combined-use surgical tools and associated systems and methods for performing surgical procedures such as identifying hidden tissue anatomy and dissecting the periphery tissues. In particular, this invention describes tools and the associated systems and methods for visualizing hidden important structures such as arteries, veins, ureters, bile duct, bowel, nodules, tumors, and performing tissue cutting using energy-based instrument. The tools are to be operated stand-alone or by attaching to existing instruments used for minimally invasive surgery.
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公开(公告)号:US20210163415A1
公开(公告)日:2021-06-03
申请号:US17167251
申请日:2021-02-04
Inventor: KENNETH DARRELL BERLIN , RICHARD A. BUNCE , KRISHNA KUMAR GNANASEKARAN , FIELD M. WATTS, JR. , DONGHUA HOWARD ZHOU
IPC: C07D215/06 , A61P35/00 , C07D335/06 , C07D311/70
Abstract: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.
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公开(公告)号:US10850836B2
公开(公告)日:2020-12-01
申请号:US15129555
申请日:2015-03-27
Inventor: Jamey D. Jacob , Weng Kheong Loh
Abstract: An embodiment of the present disclosure relates to an unmanned flying robotic object that contains a wheeled mechanism that encircles its spherical exoskeleton. This feature allows the flying spherical vehicle to readily transform into a ground maneuverable vehicle. A robotic motor with differential speed capability is used to operate each wheel to provide effective ground maneuverability. There are examples provided herein of wheel configurations suitable for use with an embodiment. One is the straight-(or parallel) wheel design, and another is tilted-wheel design as are illustrated and discussed hereinafter. One embodiment of an unmanned flying robotic object taught herein is foldable.
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公开(公告)号:US10808098B2
公开(公告)日:2020-10-20
申请号:US16123600
申请日:2018-09-06
Inventor: Jay Clarke Hanan
Abstract: A nanocomposite material comprises polyethylene terephthalate (PET) as a base polymer and a nanoparticle that increases the strength of the base polymer.
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