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公开(公告)号:WO02070707A2
公开(公告)日:2002-09-12
申请号:PCT/US0149168
申请日:2001-12-18
Applicant: CURAGEN CORP , COR THERAPEUTICS INC , PADIGARU MURALIDHARA , GERLACH VALERIE L , SMITHSON GLENNDA , STONE DAVID , BIN-YANG RUEY , CONLEY PAMELA , HART MATTHEW , TOMLINSON JAMES E , TOPPER JAMES N , KEKUDA RAMESH , CASMAN STACIE J , EDINGER SCHLOMIT , MACDOUGALL JOHN R
Inventor: PADIGARU MURALIDHARA , GERLACH VALERIE L , SMITHSON GLENNDA , STONE DAVID , BIN-YANG RUEY , CONLEY PAMELA , HART MATTHEW , TOMLINSON JAMES E , TOPPER JAMES N , KEKUDA RAMESH , CASMAN STACIE J , EDINGER SCHLOMIT , MACDOUGALL JOHN R
IPC: A61K38/00 , C07K14/705 , C12N15/12 , A61K31/7088 , A61K38/17 , A61K39/395 , C07K16/28 , C12N15/63 , C12Q1/68 , G01N33/50 , G01N33/53
CPC classification number: C07K14/705 , A61K38/00 , A61K2039/505
Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Abstract translation: 本文公开了编码G偶联蛋白 - 受体相关多肽的核酸序列。 还公开了由这些核酸序列编码的多肽,以及免疫特异性结合多肽的抗体以及上述多肽,多核苷酸或抗体的衍生物,变体,突变体或片段。 本发明还公开了用于诊断,治疗和预防与这些新型人核酸和蛋白质中的任一种相关的病症的治疗,诊断和研究方法。
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公开(公告)号:WO2002085922A2
公开(公告)日:2002-10-31
申请号:PCT/US2002/011634
申请日:2002-04-11
Applicant: CURAGEN CORPORATION , MILLENNIUM PHARMACEUTICALS, INC. , PENA, Carol, E., A. , GUO, Xiaojia , SHIMKETS, Richard, A. , PADIGARU, Muralidhara , KEKUDA, Ramesh , SPYTEK, Kimberly, A. , MEHRABAN, Fuad , TOPPER, James, N. , MALYANKAR, Uriel, M. , WASSERMAN, Scott , EDINGER, Schlomit , SMITHSON, Glennda , GUNTHER, Erik , KOMUVES, Laszlo
Inventor: PENA, Carol, E., A. , GUO, Xiaojia , SHIMKETS, Richard, A. , PADIGARU, Muralidhara , KEKUDA, Ramesh , SPYTEK, Kimberly, A. , MEHRABAN, Fuad , TOPPER, James, N. , MALYANKAR, Uriel, M. , WASSERMAN, Scott , EDINGER, Schlomit , SMITHSON, Glennda , GUNTHER, Erik , KOMUVES, Laszlo
IPC: C07K
CPC classification number: C07K14/47
Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
Abstract translation: 公开了编码它们的多肽和核酸。 还公开了用于产生多肽和多核苷酸的载体,宿主细胞,抗体和重组方法,以及使用它们的方法。 p>
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公开(公告)号:WO0216599A2
公开(公告)日:2002-02-28
申请号:PCT/US0126510
申请日:2001-08-27
Applicant: CURAGEN CORP , COR THERAPEUTICS INC , BURGESS CATHERINE E , CONLEY PAMELA B , GROSSE WILLIAM M , HART MATTHEW , KEKUDA RAMESH , SHIMKETS RICHARD A , SPYTEK KIMBERLY A , SZEKERES EDWARD S JR , TOMLINSON JAMES E , TOPPER JAMES N , YANG RUEY BIN
Inventor: BURGESS CATHERINE E , CONLEY PAMELA B , GROSSE WILLIAM M , HART MATTHEW , KEKUDA RAMESH , SHIMKETS RICHARD A , SPYTEK KIMBERLY A , SZEKERES EDWARD S JR , TOMLINSON JAMES E , TOPPER JAMES N , YANG RUEY-BIN
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses tehrapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Abstract translation: 本文公开了编码新型多肽的核酸序列。 还公开了由这些核酸序列编码的多肽,以及免疫特异性结合多肽的抗体以及前述多肽,多核苷酸或抗体的衍生物,变体,突变体或片段。 本发明还公开了用于诊断,治疗和预防与这些新型人核酸和蛋白质中的任何一种相关的病症的治疗,诊断和研究方法。
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公开(公告)号:WO02085922A3
公开(公告)日:2003-05-30
申请号:PCT/US0211634
申请日:2002-04-11
Applicant: CURAGEN CORP , MILLENNIUM PHARM INC , PENA CAROL E A , GUO XIAOJIA , SHIMKETS RICHARD A , PADIGARU MURALIDHARA , KEKUDA RAMESH , SPYTEK KIMBERLY A , MEHRABAN FUAD , TOPPER JAMES N , MALYANKAR URIEL M , WASSERMAN SCOTT , EDINGER R SHLOMIT , SMITHSON GLENNDA , GUNTHER ERIK , KOMUVES LASZLO
Inventor: PENA CAROL E A , GUO XIAOJIA , SHIMKETS RICHARD A , PADIGARU MURALIDHARA , KEKUDA RAMESH , SPYTEK KIMBERLY A , MEHRABAN FUAD , TOPPER JAMES N , MALYANKAR URIEL M , WASSERMAN SCOTT , EDINGER R SHLOMIT , SMITHSON GLENNDA , GUNTHER ERIK , KOMUVES LASZLO
CPC classification number: C07K14/47
Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
Abstract translation: 公开了编码相同的多肽和核酸。 还公开了用于产生多肽和多核苷酸的载体,宿主细胞,抗体和重组方法,以及使用它们的方法。
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公开(公告)号:WO2002016599A3
公开(公告)日:2002-02-28
申请号:PCT/US2001/026510
申请日:2001-08-27
Applicant: CURAGEN CORPORATION , COR THERAPEUTICS, INC. , BURGESS, Catherine, E. , CONLEY, Pamela, B. , GROSSE, William, M. , HART, Matthew , KEKUDA, Ramesh , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , SZEKERES, Edward, S., Jr. , TOMLINSON, James, E. , TOPPER, James, N. , YANG, Ruey-Bin
Inventor: BURGESS, Catherine, E. , CONLEY, Pamela, B. , GROSSE, William, M. , HART, Matthew , KEKUDA, Ramesh , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , SZEKERES, Edward, S., Jr. , TOMLINSON, James, E. , TOPPER, James, N. , YANG, Ruey-Bin
IPC: C12N15/00
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses tehrapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号:WO2002070707A3
公开(公告)日:2002-09-12
申请号:PCT/US2001/049168
申请日:2001-12-18
Applicant: CURAGEN CORPORATION , COR THERAPEUTICS, INC. , PADIGARU, Muralidhara , GERLACH, Valerie, L. , SMITHSON, Glennda , STONE, David , BIN-YANG, Ruey , CONLEY, Pamela , HART, Matthew , TOMLINSON, James, E. , TOPPER, James, N. , KEKUDA, Ramesh , CASMAN, Stacie, J. , EDINGER, Schlomit , MACDOUGALL, John, R.
Inventor: PADIGARU, Muralidhara , GERLACH, Valerie, L. , SMITHSON, Glennda , STONE, David , BIN-YANG, Ruey , CONLEY, Pamela , HART, Matthew , TOMLINSON, James, E. , TOPPER, James, N. , KEKUDA, Ramesh , CASMAN, Stacie, J. , EDINGER, Schlomit , MACDOUGALL, John, R.
IPC: C12N15/12
Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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