公开(公告)号：WO2007109228A1

公开(公告)日：2007-09-27

申请号：PCT/US2007/006809

申请日：2007-03-19

Applicant: NATIONAL INSTITUTES OF HEALTH ,  UNIVERSITY OF MARYLAND OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  GOMEZ, Romel, Del Rosario ,  KHAN, Javed ,  PANDANA, Herman ,  ASCHENBACH, Konrad ,  FUHRER, Michael ,  WEI, Jun

Inventor： GOMEZ, Romel, Del Rosario ,  KHAN, Javed ,  PANDANA, Herman ,  ASCHENBACH, Konrad ,  FUHRER, Michael ,  WEI, Jun

IPC: C12Q1/68

CPC classification number: G01N33/5438 ,  B82Y15/00 ,  B82Y30/00 ,  Y10S977/702 ,  Y10S977/92 ,  Y10S977/938

Abstract: A microarray apparatus is provided which contains at least one chip having source and drain electrodes positioned on an array of carbon nanotube transistors which allows for electronic detection of nucleic acid hybridizations, thereby affording both increased sensitivity and the capability of miniaturization.

Abstract translation: 提供一种微阵列装置，其包含至少一个芯片，其具有位于碳纳米管晶体管阵列上的源极和漏极，其允许电子检测核酸杂交，从而提供增加的灵敏度和小型化的能力。

公开(公告)号：WO2014062985A1

公开(公告)日：2014-04-24

申请号：PCT/US2013/065548

申请日：2013-10-17

Applicant: UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  CHILDREN'S NATIONAL MEDICAL CENTER ,  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH

Inventor： AYYUB, Omar Bilal ,  BEHRENS, Adam Michael ,  KOFINAS, Peter ,  SUMMAR, Marshall Lynn ,  CABRERA-LUQUE, Juan Manuel ,  CUNNINGHAM, Gary ,  SIMEONOV, Anton ,  MARUGAN, Juan

IPC: G01N17/04 ,  G01F1/64 ,  C12N9/00 ,  C12N11/00

CPC classification number: C12Q1/005 ,  C12N9/0018 ,  C12N9/0071 ,  C12N11/04 ,  C12N11/10 ,  G01N27/3277 ,  G01N33/6812 ,  G01N2800/04 ,  G01N2800/52

Abstract: The present invention relates to a biosensor capable of measuring the total concentration of one or a plurality of amino acids with the use of a reagentless system comprising an electrode modified by hydrogel that comprises at least one enzyme that oxidizes at least one substrate that is at least one amino acid. In some embodiments, the biosensor comprises a hydrogel comprising alginate. In some embodiments, the biosensor comprises use of a thermophilic bacterial metabolic enzyme immobilized or attached to the hydrogel.

Abstract translation: 本发明涉及能够使用包含由水凝胶改性的电极的无试剂系统来测量一种或多种氨基酸的总浓度的生物传感器，该电极包含至少一种氧化至少一种至少一种至少一种底物的酶 一个氨基酸。 在一些实施方案中，生物传感器包含包含藻酸盐的水凝胶。 在一些实施方案中，生物传感器包括使用固定或附着在水凝胶上的嗜热细菌代谢酶。

公开(公告)号：WO2007084700A3

公开(公告)日：2007-07-26

申请号：PCT/US2007/001501

申请日：2007-01-19

Applicant: UNIVERSITY OF MARYLAND OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  WEN, Xingzhi ,  VISHKIN, Uzi, Yehoshua

Inventor： WEN, Xingzhi ,  VISHKIN, Uzi, Yehoshua

IPC: G06F9/48

Abstract: An Explicit Multi-Threading (XMT) system and method is provided for processing multiple spawned threads associated with SPAWN-type commands of an XMT program. The method includes executing a plurality of child threads by a plurality of TCUs including a first TCU executing a child thread which is allocated to it; completing execution of the child thread by the first TCU; announcing that the first TCU is available to execute another child thread; executing by a second TCU a parent child thread that includes a nested spawn-type command for spawning additional child threads of the plurality of child threads, wherein the parent child thread is related in a parent-child relationship to the child threads that are spawned in conjunction with the nested spawn-type command; assigning a thread ID (TID) to each child thread, wherein the TID is unique with respect to the other TIDs; and allocating a new child thread to the first TCU.

公开(公告)号：US10392646B2

公开(公告)日：2019-08-27

申请号：US14436844

申请日：2013-10-17

Applicant: UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  CHILDREN'S NATIONAL MEDICAL CENTER ,  THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human

Inventor： Omar Bilal Ayyub ,  Adam Michael Behrens ,  Peter Kofinas ,  Marshall Lynn Summar ,  Juan Manuel Cabrera-Luque ,  Gary Cunningham ,  Anton Simeonov ,  Juan Marugan

IPC: G01N33/68 ,  C12N9/02 ,  C12N9/06 ,  C12Q1/00 ,  C12N11/04 ,  C12N11/10 ,  G01N27/327

Abstract: The present invention relates to a biosensor capable of measuring the total concentration of one or a plurality of amino acids with the use of a reagentless system comprising an electrode modified by hydrogel that comprises at least one enzyme that oxidizes at least one substrate that is at least one amino acid. In some embodiments, the biosensor comprises a hydrogel comprising alginate. In some embodiments, the biosensor comprises use of a thermophilic bacterial metabolic enzyme immobilized or attached to the hydrogel.

公开(公告)号：US09655679B2

公开(公告)日：2017-05-23

申请号：US13875204

申请日：2013-05-01

Applicant: UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION

Inventor： Jaydev P. Desai ,  Elif Ayvali

IPC: A61B1/00 ,  A61B19/00 ,  A61B17/34 ,  A61B90/11 ,  A61B1/04 ,  A61B17/00 ,  A61B90/00 ,  A61B34/20

CPC classification number: A61B90/11 ,  A61B17/3417 ,  A61B17/3421 ,  A61B90/39 ,  A61B2017/003 ,  A61B2017/00867 ,  A61B2034/2055 ,  A61B2090/3735

Abstract: A steerable probe having high-power-density actuators positioned at joints along the length of the probe. The actuators are moveable about and between a straight position and a curved position in response to selective actuation.

公开(公告)号：US20140147097A1

公开(公告)日：2014-05-29

申请号：US14093399

申请日：2013-11-29

Applicant: University of Maryland, Office of Technology Commercialization

Inventor： Ravi GARG ,  Avinash L. VARNA ,  Adi HAJJ-AHMAD ,  Min WU

IPC: H04N5/913

CPC classification number: H04N5/913 ,  H04N2005/91342

Abstract: Various systems and methods may benefit from determination of environmental signatures in recordings. For example, such signatures may aid forensic analysis and alignment of media recordings, such as alignment of audio or video recordings. A method can include reading data representative of sensed light in a visual track of a video recording. The method can also include extracting an electric network frequency signal from the data representative of sensed light.

Abstract translation: 各种系统和方法可能受益于确定记录中的环境签名。 例如，这样的签名可以帮助对媒体记录进行取证分析和对齐，诸如对准音频或视频记录。 方法可以包括在视频记录的视频轨迹中读取表示感测光的数据。 该方法还可以包括从表示感测光的数据中提取电网频率信号。

公开(公告)号：US20160168613A1

公开(公告)日：2016-06-16

申请号：US14436844

申请日：2013-10-17

Applicant: UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  CHILDREN'S NATIONAL MEDICAL CENTER ,  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN

Inventor： Omar Bilal Ayyub ,  Adam Michael Behrens ,  Peter Kofinas ,  Marshall Lynn Summar ,  Juan Manuel Cabrera-Luque ,  Gary Cunningham ,  Anton Simeonov ,  Juan Marugan

IPC: C12Q1/00 ,  C12N11/04 ,  G01N27/327 ,  G01N33/68

CPC classification number: C12Q1/005 ,  C12N9/0018 ,  C12N9/0071 ,  C12N11/04 ,  C12N11/10 ,  G01N27/3277 ,  G01N33/6812 ,  G01N2800/04 ,  G01N2800/52

Abstract: The present invention relates to a biosensor capable of measuring the total concentration of one or a plurality of amino acids with the use of a reagentless system comprising an electrode modified by hydrogel that comprises at least one enzyme that oxidizes at least one substrate that is at least one amino acid. In some embodiments, the biosensor comprises a hydrogel comprising alginate. In some embodiments, the biosensor comprises use of a thermophilic bacterial metabolic enzyme immobilized or attached to the hydrogel.

Abstract translation: 本发明涉及能够使用包含由水凝胶改性的电极的无试剂系统来测量一种或多种氨基酸的总浓度的生物传感器，该电极包含至少一种氧化至少一种至少一种至少一种底物的酶 一个氨基酸。 在一些实施方案中，生物传感器包含包含藻酸盐的水凝胶。 在一些实施方案中，生物传感器包括使用固定或附着在水凝胶上的嗜热细菌代谢酶。

公开(公告)号：US09363467B2

公开(公告)日：2016-06-07

申请号：US14093399

申请日：2013-11-29

Applicant: University of Maryland, Office of Technology Commercialization

Inventor： Ravi Garg ,  Avinash L. Varna ,  Adi Hajj-Ahmad ,  Min Wu

IPC: H04N5/913

CPC classification number: H04N5/913 ,  H04N2005/91342

Abstract: Various systems and methods may benefit from determination of environmental signatures in recordings. For example, such signatures may aid forensic analysis and alignment of media recordings, such as alignment of audio or video recordings. A method can include reading data representative of sensed light in a visual track of a video recording. The method can also include extracting an electric network frequency signal from the data representative of sensed light.

Abstract translation: 各种系统和方法可能受益于确定记录中的环境签名。 例如，这样的签名可以帮助对媒体记录进行取证分析和对齐，诸如对准音频或视频记录。 方法可以包括在视频记录的视频轨迹中读取表示感测光的数据。 该方法还可以包括从表示感测光的数据中提取电网频率信号。

公开(公告)号：US20140314706A1

公开(公告)日：2014-10-23

申请号：US14208820

申请日：2014-03-13

Applicant: University of Maryland, Office of Technology Commercialization

Inventor： Kevin Diehn ,  Matthew Dowling ,  Srinivasa R. Raghavan ,  David R. King

IPC: A61K31/765

CPC classification number: A61K31/734 ,  A61K31/717 ,  A61K31/722 ,  A61K38/39

Abstract: A hemostatic putty for treatment of a variety of wounds topographies, including but not limited to highly three dimensional wounds, for example gunshot wounds and impalements, is disclosed. The putty is comprised of a matrix polymer weakly crosslinked or not crosslinked such that a viscoelastic matrix is formed. The viscoelastic nature of the putty is tunable by the composition and enables the putty to conform to a variety of wound topographies. Likewise, a hemostatic polymer, for example chitosan or hydrophobically modified chitosan, is included in this matrix to impart hemostatic properties and tissue adhesive on the putty. The hemostatic polymers disclosed prevent microbial infection and are suitable for oxygen transfer required during normal wound metabolism.

Abstract translation: 公开了用于治疗各种伤口形态的止血腻子，包括但不限于高度三维伤口，例如枪伤和刺痛。 油灰由弱交联或未交联的基质聚合物组成，使得形成粘弹性基质。 腻子的粘弹性质可以通过组合物调节，并使腻子符合各种伤口形貌。 同样地，在该基质中包括止血聚合物，例如壳聚糖或疏水改性的壳聚糖，以在腻子上赋予止血性和组织粘合剂。 所公开的止血聚合物防止微生物感染，并且适合于正常伤口代谢期间所需的氧传递。

公开(公告)号：US20140129967A1

公开(公告)日：2014-05-08

申请号：US14071269

申请日：2013-11-04

Applicant: University of Maryland, Office of Technology Commercialization

Inventor： Hanan SAMET ,  Brendan C. FRUIN

IPC: G06F3/048

CPC classification number: G06F1/1626 ,  G06F1/1694 ,  G06F3/0346

Abstract: Various devices may benefit from determinations of how users are using the devices. For example, hand-held or hand-operated devices may benefit from handedness detection and from modifications based on or related to such detection. A method can include determining a used hand of a user of a device. The method can also include modifying a graphical user interface of the device based on the determined used hand, wherein determination of the used hand occurs prior to any querying of the user regarding the used hand of the user.

Abstract translation: 各种设备可能受益于用户如何使用设备的确定。 例如，手持式或手动操作的装置可以从旋律检测和基于或与其相关的修改中获益。 方法可以包括确定设备的用户的使用手。 该方法还可以包括基于所确定的使用手来修改设备的图形用户界面，其中在用户对用户的使用手的任何查询之前发生所使用的手的确定。