公开(公告)号：AU2004286277A1

公开(公告)日：2005-05-12

申请号：AU2004286277

申请日：2004-10-28

Applicant: REDDY US THERAPEUTICS INC ,  YELESWARAPU RAO ,  PAL MANOJIT ,  VEDULA SHARMA ,  VENKATESWARLU AKELLA ,  PILLARISETTI RAM

Inventor： RAO YELESWARAPU KOTESWAR ,  PILLARISETTI RAM ,  PAL MANOJIT ,  VENKATESWARLU AKELLA ,  SHARMA VEDULA MANOHAR

IPC: C07D311/12 ,  A61K31/35 ,  A61K31/425 ,  A61K31/497 ,  C07D215/56 ,  C07D239/90 ,  C07D277/34 ,  C07D311/30 ,  C07D417/12 ,  C07D417/14 ,  C07D487/00 ,  C07D487/04

Abstract: Compounds of formula (I), and methods and/or compositions comprising compounds that are effective in modulating inflammatory responses, such as those resulting from AGE and glycated protein accumulation are provided. Methods and/or compositions comprising compounds that are effective in modulating smooth muscle cell proliferation and the diseases or conditions related thereto are also provided.

公开(公告)号：US20050119269A1

公开(公告)日：2005-06-02

申请号：US10976284

申请日：2004-10-28

Applicant: Yeleswarapu Rao ,  Manojit Pal ,  Vedula Sharma ,  Akella Venkateswarlu ,  Ram Pillarisetti

Inventor： Yeleswarapu Rao ,  Manojit Pal ,  Vedula Sharma ,  Akella Venkateswarlu ,  Ram Pillarisetti

IPC: A61K31/427 ,  A61K31/519 ,  A61K31/525 ,  C07D215/56 ,  C07D239/88 ,  C07D239/90 ,  C07D311/30 ,  C07D401/12 ,  C07D417/12 ,  C07D417/14 ,  C07D475/02 ,  C07D487/02 ,  C07D487/04

CPC classification number: C04B35/632 ,  A61K31/427 ,  C07D215/56 ,  C07D239/88 ,  C07D239/90 ,  C07D311/30 ,  C07D401/12 ,  C07D417/12 ,  C07D417/14 ,  C07D487/04

Abstract: Compounds of formula (I), and methods and/or compositions comprising compounds that are effective in modulating inflammatory responses, such as those resulting from AGE and glycated protein accumulation are provided. Methods and/or compositions comprising compounds that are effective in modulating smooth muscle cell proliferation and the diseases or conditions related thereto are also provided.

Abstract translation: 提供了式（I）化合物，以及包含有效调节炎性反应的化合物的方法和/或组合物，例如由AGE和糖化蛋白质积聚产生的化合物。 还提供了包含有效调节平滑肌细胞增殖的化合物和与之有关的疾病或病症的方法和/或组合物。