公开(公告)号：KR101024611B1

公开(公告)日：2011-03-25

申请号：KR1020080030406

申请日：2008-04-01

Applicant: (주)뉴메드

Inventor： 김호철 ,  부영민 ,  김미연 ,  박주연 ,  임동욱

IPC: A61K36/62 ,  A61P15/00

Abstract: 본 발명은 연자육(
Nelumbinis

Semen ) 추출물을 유효성분으로 함유하는 성기능 개선용 조성물에 관한 것으로, 더욱 상세하게는 물, 알코올 또는 이들의 혼합물을 용매로 하여 추출된 연자육 추출물을 유효성분으로 함유하는 성기능 개선용 조성물에 관한 것이다. 본 발명의 연자육 추출물은 최대 음경 발기력의 상승효과와 음경 발기 유지에 효과가 있으므로 성기능 개선용 조성물, 발기부전 치료제 또는 성기능 개선용 건강식품으로 유용하게 이용될 수 있다.
연자육 추출물, 발기촉진 , 발기유지, 성기능 개선

公开(公告)号：KR1020090105133A

公开(公告)日：2009-10-07

申请号：KR1020080030406

申请日：2008-04-01

Applicant: (주)뉴메드

Inventor： 김호철 ,  부영민 ,  김미연 ,  박주연 ,  임동욱

IPC: A61K36/62 ,  A61P15/00

CPC classification number: A61K36/62 ,  A61K2236/331 ,  A61K2236/333 ,  Y10S514/906 ,  Y10S514/929

Abstract: PURPOSE: A composition for improving sexual function, which contains Nelumbinis semen extract is provided to enhance strength of erection. CONSTITUTION: A composition for improving sexual function contains Nelumbinis Semen extract as an active ingredient. The Nelumbinis Semen extract is extracted using water, alcohol or their mixture. The alcohol is a low alcohol of C1-C4, ethanol. The extract is obtained by extracting at 60-100 °C for 1-15 hours once to five times. A method for treating electile failure is to administer pharmaceutically effective amount of the extract to the patient.

Abstract translation: 目的：提供一种用于改善性功能的组合物，其包含Nelumbinis精液提取物以增强勃起强度。 构成：用于改善性功能的组合物含有Nelumbinis Semen提取物作为活性成分。 使用水，酒精或其混合物提取Nelumbinis Semen提取物。 醇是C1-C4，乙醇的低醇。 通过在60-100℃下提取1-15小时一次至五次获得提取物。 用于治疗选择性衰竭的方法是将药物有效量的提取物给予患者。

公开(公告)号：KR100886948B1

公开(公告)日：2009-03-09

申请号：KR1020060045488

申请日：2006-05-22

Applicant: (주)뉴메드

Inventor： 김호철 ,  정진희 ,  이대희 ,  최성미 ,  김미연

IPC: A61K31/366 ,  A61K31/35 ,  A61P25/28

Abstract: 본 발명은 당귀 추출물의 유효성분인 노다케닌(Nodakenin)을 함유하는 조성물에 관한 것으로, 상세하게는 본 발명의 당귀 추출물 유효성분인 노다케닌은 뇌허혈에 의해 유도되는 뇌신경세포 손상을 보호하는 효과를 나타내므로, 노다케닌을 포함하는 조성물은 신경세포의 사멸에 의해 발생되는 퇴행성 뇌질환의 예방 및 치료를 위한 의약품 및 건강기능식품으로 이용될 수 있다.
노다케닌(Nodakeknin), 신경세포 보호, 뇌허혈, 퇴행성 뇌질환

公开(公告)号：KR100825041B1

公开(公告)日：2008-04-24

申请号：KR1020070014784

申请日：2007-02-13

Applicant: (주)뉴메드

Inventor： 김호철 ,  정성문 ,  김미연 ,  박영미 ,  부영민

IPC: A61K36/254 ,  A61K36/232 ,  A61K36/539 ,  A61P29/00

Abstract: A composition comprising an optimized content of eleutheroside E, ligustilide and baicalin is provided to decrease leukocyte count, interleukin-6, TNF-alpha, and prostaglandin E2 and increase prostaglandin E2 synthase, thereby being usefully used in order to prevent and treat inflammatory diseases. A composition for treating and preventing inflammatory diseases such as osteoarthritis, rheumatoid arthritis and periarthritis of shoulder comprises a mixture consisting of 3-7 parts by weight of an extract of Acanthopanax senticosus, 2-6 parts by weight of an extract of Angelica sinensis and 0.8-1.2 parts by weight of an extract of Scutellaria baicalensis, wherein the extract is prepared by using a solvent such as water, C1-4 alcohol, and a mixture thereof and the mixture contains 0.5-5% of eleutheroside E, 0.05-0.5% of ligustilide and 1-10% of baicalin.

Abstract translation: 提供了包含优化内容物的组合物，其中包括优化内容物的eleutheroside E，ligustilide和黄芩苷，以减少白细胞计数，白细胞介素-6，TNF-α和前列腺素E2并增加前列腺素E2合成酶，从而有效地用于预防和治疗炎症性疾病。 用于治疗和预防炎性疾病如骨关节炎，类风湿性关节炎和肩周炎的炎性疾病的组合物包括由3-7重量份刺五加提取物，2-6重量份当归提取物和0.8 -1.2重量份的黄芩提取物，其中所述提取物通过使用溶剂如水，C 1-4醇及其混合物制备，并且所述混合物含有0.5-5％的十六烷基化合物E，0.05-0.5％ 的ligustilide和1-10％的黄芩苷。

公开(公告)号：KR100818204B1

公开(公告)日：2008-04-02

申请号：KR1020070090398

申请日：2007-09-06

Applicant: (주)뉴메드

Inventor： 김호철 ,  김미연 ,  박영미 ,  부영민 ,  김윤태 ,  임동욱

IPC: A61K36/185 ,  A61P19/00

Abstract: An extract of Viscum album var. coloratum is provided to promote the growth of bone length effectively, thereby being usefully used as a pharmaceutical composition and a health supplement food for promoting the bone length growth. A pharmaceutical composition for promoting bone growth comprises an extract of Viscum album var. coloratum, which is prepared by extracting leaves or stems of the Viscum album var. coloratum with water, C1-4 alcohol or a mixture thereof as a solvent for 1-24 hours. Further, an added weight of the solvent is 1 to 10 times as large as the Viscum album var. coloratum.

Abstract translation: Viscum album var。 提供了色素以有效地促进骨长度的生长，从而有效地用作促进骨长度生长的药物组合物和健康补充食品。 用于促进骨生长的药物组合物包括Viscum album var。 通过提取Viscum相册变种的叶子或茎来制备。 色素与水，C 1-4醇或其混合物作为溶剂1-24小时。 此外，溶剂的添加重量为Viscum album var的1〜10倍。 coloratum。

公开(公告)号：KR1020100130578A

公开(公告)日：2010-12-13

申请号：KR1020100116349

申请日：2010-11-22

Applicant: (주)뉴메드

Inventor： 김호철 ,  부영민 ,  김미연 ,  박주연 ,  임동욱

IPC: A61K36/62 ,  A61P15/00

CPC classification number: A61K36/62 ,  A61K2236/331 ,  A61K2236/333 ,  Y10S514/906 ,  Y10S514/929

Abstract: PURPOSE: A composition containing Nelumbinis Semen extract for improving sexual function is provided to maximize and maintain penis erection. CONSTITUTION: A composition for improving sexual function contains Nelumbinis Semen extract as an active ingredient. The Nelumbinis Semen extract is isolated using a solvent at 60-100°C for 1-15 hours once to five times. A therapeutic agent for impotence contains the Nelumbinis Semen extract as an active ingredient. A health food for improving sexual function contains Nelumbinis Semen extract as an active ingredient, isolated using solvent.

Abstract translation: 目的：提供含有Nelumbinis精液提取物以改善性功能的组合物，以最大化和维持阴茎勃起。 构成：用于改善性功能的组合物含有Nelumbinis Semen提取物作为活性成分。 使用溶剂在60-100℃下分离Nelumbinis Semen提取物1-15小时一次至五次。 阳A治疗剂含有Nelumbinis Semen提取物作为活性成分。 用于改善性功能的保健食品含有Nelumbinis Semen提取物作为活性成分，使用溶剂分离。

公开(公告)号：KR100855741B1

公开(公告)日：2008-09-03

申请号：KR1020070020906

申请日：2007-03-02

Applicant: (주)뉴메드

Inventor： 김호철 ,  김윤태 ,  정진희 ,  김진화 ,  김미연 ,  부영민

IPC: A61K36/488 ,  A61P9/10

CPC classification number: Y02A20/402 ,  A61K36/488 ,  A23L33/105 ,  A23V2200/322 ,  A23V2250/21172 ,  A61K2236/33 ,  Y10S514/822

Abstract: A composition comprising the extract of Puerariae Radix or daidzein isolated therefrom is provided to protect damage of nerve cells in CA1(Cornu Ammonis) region of the human hippocampus and inhibit harmful effects on human, so that the composition is useful to prevent or treat ischemic cerebral diseases caused by apoptosis of nerve cells. A composition for prevention or treatment of ischemic cerebral diseases except vascular dementia caused by apoptosis of nerve cells comprises the extract of Puerariae Radix which is prepared by extracting Puerariae Radix with water, C1-C3 lower alcohol or a mixture thereof, or 0.001 to 50 wt.% of daidzein isolated therefrom which is isolated from the ethylacetate fraction of the Puerariae Radix extract, wherein the ischemic cerebral diseases include thrombosis, em-bolism, transient ischemic attack, lacune, cerebral apoplexy, cerebral hemorrhage, cerebral infarction, head trauma or cerebral circulation metabolic disorder.

Abstract translation: 提供包含葛根提取物或从其分离的黄豆苷原的组合物，以保护人类海马CA1（Cornu Ammonis）区域神经细胞的损伤并抑制对人的有害影响，从而该组合物可用于预防或治疗缺血性脑 由神经细胞凋亡引起的疾病。 用于预防或治疗由神经细胞凋亡引起的血管性痴呆以外的缺血性脑疾病的组合物包括葛根提取物，其通过用水，C1-C3低级醇或其混合物提取葛根，或0.001至50重量％ 从葛根提取物的乙酸乙酯部分中分离出的大豆黄素的百分比，其中缺血性脑疾病包括血栓形成，肺栓塞，短暂性脑缺血发作，泪液，脑中风，脑出血，脑梗塞，头部创伤或脑 循环代谢紊乱。

公开(公告)号：KR1020070112507A

公开(公告)日：2007-11-27

申请号：KR1020060045488

申请日：2006-05-22

Applicant: (주)뉴메드

Inventor： 김호철 ,  정진희 ,  이대희 ,  최성미 ,  김미연

IPC: A61K31/366 ,  A61K31/35 ,  A61P25/28

Abstract: A composition comprising nodakenin is provided to protect brain cells from damage induced by ischemia, thereby being used as medicines and health functional foods for preventing and treating degenerative diseases generated by extinction of neurons. A pharmaceutical composition for preventing and treating degenerative brain diseases such as stroke, palsy, dementia, Alzheimer's disease, Parkinson's disease, huntington's disease, Pick's disease or Creutzfeld-Jakob disease comprises nodakenin isolated from roots of Angelica gigas Nakai and represented by the formula(A) having neuronal cell-protecting activity as an effective ingredient. A health functional food comprises the nodakenin and a sitologically acceptable food additive.

Abstract translation: 提供包含止血蛋白的组合物以保护脑细胞免受缺血诱导的损伤，从而用作用于预防和治疗由神经元灭绝产生的退行性疾病的药物和健康功能食品。 用于预防和治疗退行性脑疾病如中风，麻痹，痴呆，阿尔茨海默氏病，帕金森病，亨廷顿舞蹈病，皮克病或克雅氏病的药物组合物包括从当归根中分离出并由式（A ）具有神经元细胞保护活性作为有效成分。 健康功能食品包括nodakenin和一种可视觉可接受的食品添加剂。