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公开(公告)号:KR101335575B1
公开(公告)日:2013-12-02
申请号:KR1020130010580
申请日:2013-01-30
Applicant: (주)에스.앤.디
IPC: A61K31/4045 , A61K31/135 , A61K36/286 , A61K36/906
Abstract: 본 발명은 고지혈증 치료 및 예방관련한 HMG-CoR 저해효과와 ACAT저해 효과를 나타내는 페닐아마이드 화합물을 유효성분으로 하는 고지혈증 치료용 복합 생약 추출물에 관한 것으로, 상세하게는 천연물인 홍화씨 생강 복합 추출물로 구성된 고지혈증 치료용 조성물에 관한 것이다. 또한 본 발명은 각 추출물로부터 인체에 부작용 또는 독성 등의 우려가 없고 고지혈증 치료 및 예방을 목적으로 하는 페닐아마이드 물질의 제조방법에 관한 것이다.
Abstract translation: 本发明涉及一种用于治疗高脂血症的组合的草药提取物来表示高脂血症治疗和预防相关的HMG-COR抑制活性和ACAT抑制活性作为活性成分,尤其是由天然产物红花姜合并的萃取物的高脂血症治疗苯基酰胺化合物 < 本发明还涉及用于制备苯酰胺材料用于治疗和预防高血脂的目的的过程中,有没有从各提取物等副作用或毒性对人体可能性。
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公开(公告)号:KR101434471B1
公开(公告)日:2014-08-27
申请号:KR1020120118186
申请日:2012-10-24
Applicant: (주)에스.앤.디
IPC: A61K36/282 , A61K36/258 , A61K36/82 , A61P35/00
Abstract: 본 발명은 천연물 유래 당 배합체를 이용한 위염 및 암 예방 조성물과 그 제조방법에 관한 것으로, 더욱 상세하게는 인진쑥, 인삼 및 녹차로 이루어진 그룹에서 선택된 하나 이상으로 이루어진 약초 추출물을 함유한 위염 및 암 예방 조성물로, 그 제조방법은 약초에 정제수를 투입하고 약초 추출물을 추출하는 추출단계, 상기 추출단계를 통해 추출된 추출액을 여과하고 농축하는 여과농축단계, 상기 여과농축단계를 통해 생성된 생성물을 여액과 침전물로 분리하고 결정화시키는 결정화단계 및 상기 결정화단계를 통해 분리된 결정을 건조시킨 후 분쇄하여 분말화하는 건조분말화단계로 이루어진다.
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公开(公告)号:KR1020130025422A
公开(公告)日:2013-03-11
申请号:KR1020130010581
申请日:2013-01-30
Applicant: (주)에스.앤.디
IPC: A61K31/4045 , A61K31/135 , A61K36/286 , A61K36/906
CPC classification number: A61K31/4045 , A61K31/12 , A61K31/165 , A61K36/286 , A61K36/906 , A61K2300/00
Abstract: PURPOSE: A complex crude drug extract containing a phenylamide compound is provided to prevent and treat hyperlipidemia without side effects and toxicity. CONSTITUTION: A complex crude drug extract for treating hyperlipidemia contains a serotonin derivative, a tyramine derivative, and gingerol in a weight ratio of 5:1:1. The serotonin derivative is N-(p-coumaroyl)serotonin(CS), N-feruloylserotonin(FS), or a mixture thereof. The tyramine derivative is dihydro-N-cafferoyltyramine(DCT), trans-N-cafferoyltyramine(t-CT), or a mixture thereof. Gingerol includes 6-gingerol, 8-gingerol, or a mixture thereof. [Reference numerals] (AA) Ginger + Safflower seed; (BB) Ginger 1 : Safflower seed B8; (CC) Ginger 1 : Safflower seed B4; (DD) Ginger 1 : Safflower seed B2; (EE) Ginger 1 : Safflower seed B1; (FF) Ginger 2 : Safflower seed B1; (GG) Ginger 4 : Safflower seed B1; (HH) Ginger 8 : Safflower seed B1; (II) Ginger 1 : Safflower seed A1; (JJ) Ginger 2 : Safflower seed A1; (KK) Ginger 4 : Safflower seed A1; (LL) Ginger 8 : Safflower seed A1
Abstract translation: 目的:提供含有苯酰胺化合物的复合生物药物提取物,用于预防和治疗高脂血症,无副作用和毒性。 构成:用于治疗高脂血症的复杂生药提取物含有重量比为5:1:1的5-羟色胺衍生物,酪胺衍生物和姜油。 5-羟色胺衍生物是N-(对 - 香豆酰基)5-羟色胺(CS),N-亚铁血清素(FS)或其混合物。 酪胺衍生物是二氢-N-咖啡酰基酪氨酸(DCT),反式N-咖啡酰酪胺(t-CT)或其混合物。 姜醇包括6-姜醇,8-姜醇或其混合物。 (标号)(AA)姜+红花种子; (BB)姜1:红花种子B8; (CC)姜1:红花籽B4; (DD)姜1:红花籽B2; (EE)姜1:红花籽B1; (FF)姜2:红花籽B1; (GG)姜4:红花籽B1; (HH)姜8:红花籽B1; (二)姜1:红花籽A1; (JJ)姜2:红花籽A1; (KK)姜4:红花籽A1; (LL)姜8:红花籽A1
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公开(公告)号:KR101335576B1
公开(公告)日:2013-12-02
申请号:KR1020130010581
申请日:2013-01-30
Applicant: (주)에스.앤.디
IPC: A61K31/4045 , A61K31/135 , A61K36/286 , A61K36/906
Abstract: 본 발명은 고지혈증 치료 및 예방관련한 HMG-CoR 저해효과와 ACAT저해 효과를 나타내는 페닐아마이드 화합물을 유효성분으로 하는 고지혈증 치료용 복합 생약 추출물에 관한 것으로, 상세하게는 천연물인 홍화씨 생강 복합 추출물로 구성된 고지혈증 치료용 조성물에 관한 것이다. 또한 본 발명은 각 추출물로부터 인체에 부작용 또는 독성 등의 우려가 없고 고지혈증 치료 및 예방을 목적으로 하는 페닐아마이드 물질의 제조방법에 관한 것이다.
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公开(公告)号:KR1020140052264A
公开(公告)日:2014-05-07
申请号:KR1020120118186
申请日:2012-10-24
Applicant: (주)에스.앤.디
IPC: A61K36/282 , A61K36/258 , A61K36/82 , A61P35/00
Abstract: The present invention relates to a composition to prevent gastritis and cancer containing sugar complex from natural extract and a manufacturing method thereof and, more specifically, to a composition to prevent gastritis and cancer containing herbal extracts selected from Artemisia capillaris, ginseng, and green tea. The manufacturing method for the composition to prevent gastritis and cancer includes an extraction step to put purified water into herbs and extracting herbal extracts; a filtration and concentration step to filter and concentrate the extracted solution; a crystallization step to separate the product into a precipitate and a precipitate filtrate and crystallizing the same; and a dry and pulverization step to dry the crystals separated through the crystallization step and pulverizing the same.
Abstract translation: 本发明涉及一种预防胃炎的组合物和来自天然提取物的含糖复合物的组合物及其制备方法,更具体地,涉及一种预防胃炎的组合物和含有选自艾蒿,人参和绿茶的草药提取物的癌症。 用于预防胃炎和癌症的组合物的制备方法包括将纯化水放入草药中并提取草药提取物的提取步骤; 过滤和浓缩步骤以过滤并浓缩提取的溶液; 将产物分离成沉淀物和沉淀滤液并使其结晶的结晶步骤; 以及干燥和粉碎步骤以干燥通过结晶步骤分离的晶体并粉碎。
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公开(公告)号:KR1020130025421A
公开(公告)日:2013-03-11
申请号:KR1020130010580
申请日:2013-01-30
Applicant: (주)에스.앤.디
IPC: A61K31/4045 , A61K31/135 , A61K36/286 , A61K36/906
CPC classification number: A61K31/4045 , A61K31/165 , A61K36/286 , A61K36/906 , A61K2300/00
Abstract: PURPOSE: A complex crude drug extract containing a phenylamide compound is provided to reduce side effects and toxicity, and to treat hyperlipidemia. CONSTITUTION: A complex crude drug extract for treating hyperlipidemia contains a serotonin derivative and a tyramine derivative in a weight ratio of 4:1. The serotonin derivative is N-(p-coumaroyl)serotonin(CS), N-feruloylserotonin(FS), or a mixture thereof. The tyramine derivative is dihydro-N-caffeoyltyramine(DCT), trans-N-caffeoyltyramine(t-CT), or a mixture thereof. [Reference numerals] (AA) Ginger + Safflower seed; (BB) Ginger 1 : Safflower seed B8; (CC) Ginger 1 : Safflower seed B4; (DD) Ginger 1 : Safflower seed B2; (EE) Ginger 1 : Safflower seed B1; (FF) Ginger 2 : Safflower seed B1; (GG) Ginger 4 : Safflower seed B1; (HH) Ginger 8 : Safflower seed B1; (II) Ginger 1 : Safflower seed A1; (JJ) Ginger 2 : Safflower seed A1; (KK) Ginger 4 : Safflower seed A1; (LL) Ginger 8 : Safflower seed A1
Abstract translation: 目的:提供含有苯酰胺化合物的复合生物药物提取物,以减少副作用和毒性,并治疗高脂血症。 构成:用于治疗高脂血症的复杂生药提取物含有重量比为4:1的5-羟色胺衍生物和酪胺衍生物。 5-羟色胺衍生物是N-(对 - 香豆酰基)5-羟色胺(CS),N-亚铁血清素(FS)或其混合物。 酪胺衍生物是二氢-N-咖啡酰基酪氨酸(DCT),反式N-咖啡酰酪胺(t-CT)或其混合物。 (标号)(AA)姜+红花种子; (BB)姜1:红花种子B8; (CC)姜1:红花籽B4; (DD)姜1:红花籽B2; (EE)姜1:红花籽B1; (FF)姜2:红花籽B1; (GG)姜4:红花籽B1; (HH)姜8:红花籽B1; (二)姜1:红花籽A1; (JJ)姜2:红花籽A1; (KK)姜4:红花籽A1; (LL)姜8:红花籽A1
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公开(公告)号:KR1020120115060A
公开(公告)日:2012-10-17
申请号:KR1020110071839
申请日:2011-07-20
Applicant: (주)에스.앤.디
IPC: A61K36/286 , A61K36/906 , A61P3/06
Abstract: PURPOSE: A complex crude drug extract for treating hyperlipidemia which contains phenyl amide compound is provided to show HMG-CoR inhibition effects and ACAT inhibition effects related to treat and prevent the hyperlipidemia. CONSTITUTION: A complex crude drug extract for treating hyperlipidemia is composed of multiple extract of safflower seed and ginger. The mixing ratio of the safflower seed to ginger is 4:1 in the weight ratio. The Lycii Radicis Cortex extract is additionally added to the extract. The mixing ration of the safflower seed, ginger extract, and the Lycii Radicis Cortex extract is 5:1:1 in the weight ratio. The complex crude drug extract for treating hyperlipidemia is composed of serotonin derivative and tyramine derivative. The mixing ratio of serotonin derivative to the tyramine derivative is 4: 1 in the weight ratio. The serotonin derivative is a mixture of N-(p-coumaroyl) serotonin(CS), N- feruloylserotonin(FS), or a mixture thereof. [Reference numerals] (AA) Ginger+safflower seed; (BB) Ginger 1 : Safflower seed B3; (CC) Ginger 1 : Safflower seed B4; (DD) Ginger 1 : Safflower seed B2; (EE) Ginger 1 : Safflower seed B1; (FF) Ginger 2 : Safflower seed B1; (GG) Ginger 4 : Safflower seed B1; (HH) Ginger 8 : Safflower seed B1; (II) Ginger 1 : Safflower seed A1; (JJ) Ginger 2 : Safflower seed A1; (KK) Ginger 4 : Safflower seed A1; (LL) Ginger 8 : Safflower seed A1
Abstract translation: 目的:提供一种用于治疗含有苯酰胺化合物的高脂血症的复合生药提取物,以显示与治疗和预防高脂血症相关的HMG-CoR抑制作用和ACAT抑制作用。 构成:用于治疗高脂血症的复方生药提取物由红花种子和姜的多次提取物组成。 红花种子与姜的混合比例为4:1。 提取物中还加入Lycii Radicis Cortex提取物。 红花种子,姜提取物和堇菜提取物的混合比例为5:1:1。 用于治疗高脂血症的复方生药提取物由5-羟色胺衍生物和酪胺衍生物组成。 5-羟色胺衍生物与酪胺衍生物的混合比例为重量比为4:1。 5-羟色胺衍生物是N-(对 - 香豆酰基)5-羟色胺(CS),N-阿魏酰基血清素(FS)或其混合物的混合物。 (标号)(AA)姜+红花种子; (BB)姜1:红花籽B3; (CC)姜1:红花籽B4; (DD)姜1:红花籽B2; (EE)姜1:红花籽B1; (FF)姜2:红花籽B1; (GG)姜4:红花籽B1; (HH)姜8:红花籽B1; (二)姜1:红花籽A1; (JJ)姜2:红花籽A1; (KK)姜4:红花籽A1; (LL)姜8:红花籽A1
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