公开(公告)号：KR1020140094295A

公开(公告)日：2014-07-30

申请号：KR1020130006929

申请日：2013-01-22

Applicant: 가톨릭대학교 산학협력단

Inventor： 박용일 ,  조항수 ,  최두진 ,  정미자

IPC: A61K36/07 ,  A61K31/70 ,  A61P25/28 ,  A61P25/00

CPC classification number: A61K31/716 ,  A23L29/035 ,  A23V2200/322 ,  A61K36/07

Abstract: Provided are an anti-Alzheimer′s pharmaceutical composition and a functional health food for alleviating Alzheimer′s, wherein a water-soluble monomer derived from a hot water extract of a Phellinus linteus fruit body is contained as an active ingredient. The pharmaceutical composition and functional health food according to the present invention inhibit the activity of beta secretase related to the production and accumulation of beta amyloid peptides which are considered to be the cause of Alzheimer′s. Accordingly, the pharmaceutical composition containing water-soluble polysaccharides can be utilized as a medical product or a functional health food for preventing or treating Alzheimer′s.

Abstract translation: 提供抗阿尔茨海默氏病药物组合物和用于缓解阿尔茨海默病的功能保健食品，其中含有源自桑黄果实体的热水提取物的水溶性单体作为活性成分。 根据本发明的药物组合物和功能保健食品抑制与被认为是阿尔茨海默氏病原因的β淀粉样蛋白肽的产生和积累相关的β分泌酶的活性。 因此，含有水溶性多糖的药物组合物可以用作医疗产品或用于预防或治疗阿尔茨海默病的功能保健食品。