公开(公告)号：KR101333669B1

公开(公告)日：2013-11-28

申请号：KR1020120122775

申请日：2012-11-01

Applicant: 강원대학교산학협력단

Inventor： 이정형 ,  민병선 ,  강정원

IPC: A61K31/05 ,  A61K31/045 ,  A61P9/10 ,  A61P9/00

Abstract: The present invention relates to a composition containing erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan for preventing or treating vascular diseases. The composition containing erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan effectively suppresses platelet aggregation, thereby being used as a composition for effectively preventing and suppressing vascular diseases including thrombosis, arteriosclerosis, angina pectoris, myocardial infarction, ischemic heart disease, heart failure, complications after percutaneous transluminal coronary angioplasty, cerebral infarction, cerebral hemorrhage, and stroke. [Reference numerals] (AA,BB,CC) Blood platelet cohesion activation (%)

Abstract translation: 本发明涉及含有用于预防或治疗血管疾病的红 - （7S，8R）-7-乙酰氧基-3,4,3'，5'-四甲氧基-8-O-4'-新替尼利因的组合物。 含有红 - （7S，8R）-7-乙酰氧基-3,4,3'，5'-四甲氧基-8-O-4'-新衣肉酸酯的组合物有效地抑制血小板聚集，从而被用作有效预防和/ 抑制血管疾病，包括血栓形成，动脉硬化，心绞痛，心肌梗塞，缺血性心脏病，心力衰竭，经皮腔内冠状动脉成形术，脑梗塞，脑出血和中风后的并发症。 （附图标记）（AA，BB，CC）血小板内聚活化（％）