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Patent Agency Ranking
公开(公告)号：KR101095401B1
公开(公告)日：2011-12-16
申请号：KR1020110036682
申请日：2011-04-20
Applicant: 강원대학교산학협력단
IPC: A61K31/352 , A61K31/353 , A61P17/00 , A61P27/14
Abstract: PURPOSE: A composition containing eupatilin for treating allergic diseases is provided to suppress reactive oxygen species(ROS) and phox gene expression. CONSTITUTION: A pharmaceutical composition for preventing and treating allergic disorder contains 10-1000ug/ml of eupatilin as an active ingredient. The eupatilin is isolated from Artemisia asiatica Nakai. The allergic disorders are atopic dermatitis, hives, or allergic rhinitis. A cosmetic composition for preventing and treating allergic disorder contains 10-1000 ug/ml of eupatilin as an active ingredient.
Abstract translation: 目的：提供含有用于治疗过敏性疾病的醋酸蛋白酶的组合物，以抑制活性氧（ROS）和phox基因表达。 构成：用于预防和治疗过敏性疾病的药物组合物含有10-1000ug / ml的作为活性成分的胡萝卜素。 艾蒿素是从艾蒿（Asematica Nakai）中分离出来的。 过敏性疾病是特应性皮炎，荨麻疹或过敏性鼻炎。 用于预防和治疗过敏性疾病的化妆品组合物含有10-1000ug / ml的作为活性成分的依帕替林。
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公开(公告)号：KR1020110131452A
公开(公告)日：2011-12-07
申请号：KR1020100050897
申请日：2010-05-31
Applicant: 강원대학교산학협력단
IPC: A61K36/81 , A61K31/7048 , A61K31/352 , A61P29/00
CPC classification number: A61K31/7048 , A23L29/035 , A61K36/81 , Y10S514/825 , Y10S514/857 , Y10S514/886 , Y10S514/8995
Abstract: PURPOSE: A composition containing violet pigment isolated from Solanum tuberosum L. for preventing and treating inflammation is provided to reduce TNA-alpha and IL-6 generation. CONSTITUTION: A composition for preventing and treating inflammation contains violet pigment as an active ingredient, isolated from Solanum tuberosum L. A composition for preventing and treating inflammatory disease contains anthocyanin violet pigment of chemical formula 1 as an active ingredient. A health food for preventing and treating inflammatory diseases contains the compound of chemical formula 1 as an active ingredient.
Abstract translation: 目的：提供一种含有从马铃薯Solanum tuberosum L.分离的紫色素用于预防和治疗炎症的组合物，以减少TNA-α和IL-6的产生。 构成：用于预防和治疗炎症的组合物含有紫罗兰色素作为活性成分，从马铃薯（Solanum tuberosum L.）中分离。用于预防和治疗炎性疾病的组合物含有化学式1的花青素紫色素作为活性成分。 用于预防和治疗炎性疾病的保健食品含有化学式1的化合物作为活性成分。
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公开(公告)号：KR101175195B1
公开(公告)日：2012-08-20
申请号：KR1020100050897
申请日：2010-05-31
Applicant: 강원대학교산학협력단
IPC: A61K36/81 , A61K31/7048 , A61K31/352 , A61P29/00
Abstract: 본발명은유색감자로부터분리된자색색소를함유하는염증예방및 치료용조성물에관한것으로서, 더욱상세하게는유색감자로부터분리된자색색소가염증성질환을야기하는것으로알려진 NO 생성과 TNF-a 및 IL-6 생성을농도의존적으로감소시킴을확인함으로써염증성질환의예방및 치료와건강식품의재료로유용하게사용될수 있는유색감자로부터분리된자색색소를함유하는염증예방및 치료용조성물에관한것이다.
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公开(公告)号：KR1020110025370A
公开(公告)日：2011-03-10
申请号：KR1020090083403
申请日：2009-09-04
Applicant: 강원대학교산학협력단
IPC: C07D311/78 , A61K31/7028
Abstract: PURPOSE: A novel compound petunanin JY isolated from color potatoes and a method for preparing the same are provided to ensure antioxidation and anticancer activities without side effects. CONSTITUTION: A novel compound, petunanin JY is denoted by chemical formula 1. The compound of chemical formula 1 or salt thereof is isolated from color potato, Solanum tuberosum L. cv Jayoung. A method for preparing the compound of chemical formula 1 comprises: a step of extracting the color potatoes with alcohol containing acid to obtain an alcohol extract; a step of dissolving the alcohol extract in a mixture solvent of acid-containing water and alcohol and performing chromatography to concentrate the fraction; a step of dissolving the concentrate in acid-containing alcohol to collect active fractions; a step of resolving solvent and freeze-drying to obtain a target compound. An anticancer agent contains the compound of chemical formula 1 or pharmaceutically acceptable salt, or the color potato extract as an active ingredient.
Abstract translation: 目的：提供从彩色土豆中分离的新型化合物矮竹素JY及其制备方法，以确保抗氧化和抗癌活性，无副作用。 构成：化合物1表示一种新化合物，矮化素JY。化学式1或其盐的化合物与马铃薯马铃薯（Solanum tuberosum L. cv Jayoung）分离。 制备化学式1的化合物的方法包括：用含有酸的醇提取彩色马铃薯以获得醇提取物的步骤; 将醇提取物溶解在含酸水和醇的混合溶剂中并进行色谱以浓缩该级分的步骤; 将浓缩物溶解在含酸醇中以收集活性级分的步骤; 分解溶剂并冷冻干燥以获得目标化合物的步骤。 抗癌剂含有化学式1的化合物或其药学上可接受的盐，或作为活性成分的彩色马铃薯提取物。
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公开(公告)号：KR101162511B1
公开(公告)日：2012-07-05
申请号：KR1020090083403
申请日：2009-09-04
Applicant: 강원대학교산학협력단
IPC: C07D311/78 , A61K31/7028
Abstract: 본 발명은 유색감자로부터 분리한 항산화 및 항암활성을 나타내는 신규 화합물과 그의 제조방법에 관한 것으로서, 더욱 상세하게는 유색감자 자영(
Solanum tuberosum L. cv Jayoung)으로부터 분리 및 동정되어 본 출원인에 의하여 명명된 신규화합물 페츄나닌(Petunanin) JY와 그의 제조방법에 관한 것이다.
본 발명의 신규화합물은 식용식물인 유색감자로부터 분리된 것으로 정상세포에 대한 부작용이 거의 없으며, 높은 항산화활성과 항암활성을 나타내므로 항암 및 암 예방 효과와, 다양한 질병의 치료제와 함께 병용되어 질병의 치료 및 예방효과를 증대시킬 수 있으며, 암 예방과및 항산화효과를 나타내는 기능성 식품 및 항산화효과가 발현되는 기능성 화장료 등에 적용될 수 있는 등의 효과를 기대할 수 있다.
유색감자, 감자, 안토시아닌, 항산화, 항암
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