-
1.发明授权항비만 효능이 향상된 큐빅상 나노입자 및 항비만 천연추출물 혼합 현탁액 및 그 제조방법 有权CUBIC PHASE NANOPARTICLE AND HERBAL EXTRACTS MIXTURE暂停展示增强的抗生素效能及其制备方法
公开(公告)号：KR101302154B1
公开(公告)日：2013-08-30
申请号：KR1020130021061
申请日：2013-02-27
Applicant: 강원대학교산학협력단
IPC: A61K9/10 , A61K36/718 , A61K36/82 , A61K36/87
CPC classification number: A61K9/107 , A61K36/282 , A61K36/718 , A61K36/73 , A61K47/6905 , A61K47/6925
Abstract: PURPOSE: A mixture suspension for anti-obesity is provided to promote bioavailability of a natural product extract by cubic nanoparticles contained in the mixture suspension, thereby improving an anti-obesity effect of the natural product extract. CONSTITUTION: A method for manufacturing a mixture suspension for anti-obesity comprises the steps of: adding an aqueous phase to a monoolein melt solution and preparing a monoolein cubic phase; adding the monoolein cubic phase to an aqueous phase in which a dispersion is dissolved and homogenizing to prepare a cubic nanoparticle suspension; mixing the dispersion-dissolved solution and one or more natural product extracts selected among a Coptidis rhizome extract, an apple extract, and an Artemisia princeps extract and homogenizing to prepare a natural product extract suspension; and mixing the cubic nanoparticle suspension and the natural product extract suspension.
Abstract translation: 目的：提供用于抗肥胖症的混合悬浮液，以通过混合悬浮液中包含的立方纳米颗粒促进天然产物提取物的生物利用度，从而改善天然产物提取物的抗肥胖效果。 构成：制备用于抗肥胖症的混合物悬浮液的方法包括以下步骤：将水相加入到单油酸酯熔融溶液中并制备单油酸酯立方相; 将单油脂立方相加入到其中溶解分散体的水相中并均化以制备立方纳米颗粒悬浮液; 混合分散溶解的溶液和选自黄连提取物，苹果提取物和青蒿提取物中的一种或多种天然产物提取物，并均化以制备天然产物提取物悬浮液; 并将立方体纳米颗粒悬浮液和天然产物提取物悬浮液混合。
-
公开(公告)号：KR101377710B1
公开(公告)日：2014-03-21
申请号：KR1020120010920
申请日：2012-02-02
Applicant: 강원대학교산학협력단
IPC: A61K9/16 , A61K8/97 , A61K36/704 , A61Q7/00
Abstract: 본발명은백자인추출물, 적하수오추출물및 에스피노질리아추출물로이루어진군에서선택된하나이상의천연추출물이모노올레인큐빅상나노입자의수상채널에포접되어있는것을특징으로하는발모또는양모촉진용큐빅상나노입자및 그제조방법을개시한다.
-
公开(公告)号：KR1020110003135A
公开(公告)日：2011-01-11
申请号：KR1020090060753
申请日：2009-07-03
Applicant: 강원대학교산학협력단
CPC classification number: A61K9/5089 , A61K9/5031 , A61K9/5047
Abstract: PURPOSE: A microcapsule comprising a core at the center and a wall surrounding the core is provided to selectively release physiological ingredients to the outside. CONSTITUTION: A microcapsule contains: a polymer of isopropylacryl amide-methacrylic acid and a material to be captured as a core; and a non-sensitive polymer as a wall material surrounding the core. The non-sensitive polymer is ethylcellulose, poly upsilon-caprolactone, poly(lactic acid), poly(glycol acid) or poly lactic acid-co-glycolic acid.
Abstract translation: 目的：提供一种包含中心的核心和围绕核心的壁的微胶囊，以选择性地将生理成分释放到外部。 构成：微胶囊包含：异丙基丙烯酰胺 - 甲基丙烯酸的聚合物和待捕获的材料作为核心; 以及作为围绕芯的壁材料的非敏感性聚合物。 非敏感性聚合物是乙基纤维素，聚己内酯，聚（乳酸），聚（乙二醇酸）或聚乳酸 - 共 - 乙醇酸。
-
公开(公告)号：KR101077635B1
公开(公告)日：2011-10-27
申请号：KR1020090060241
申请日：2009-07-02
Applicant: 강원대학교산학협력단
Abstract: 본발명은목적물질을포집하고있는수화겔에있어서, 산성기를가지고있는산성고분자와염기성기를가지고있는염기성고분자사이에형성되는염다리의내부에목적물질이포집되어형성되는것을특징으로하는수화겔 및그의제조방법에관한것으로, 산성고분자와염기성고분자로구성된수화겔로서 pH에따라포집된목적물질을선택적으로방출하는특징이있는바, 내부에포집된항암제, 항생제, 항진균제, 항박테리아제, 항산화제, 미백제, 소염제등의다양한소수성, 친수성생리활성성분을필요한상황에따라선택적으로외부에방출시킬수 있는효과를발휘한다.
-
Patent Agency Ranking
公开(公告)号：KR1020110002659A
公开(公告)日：2011-01-10
申请号：KR1020090060241
申请日：2009-07-02
Applicant: 강원대학교산학협력단
Abstract: PURPOSE: A hydrogel is provided to selectively discharge target materials according to pH and to be prepared without a chemical cross-linker. CONSTITUTION: A method for preparing hydrogel comprises the steps of: dissolving an acidic polymer with an acidic group and pH value lower than pH of water to prepare an acidic polymer solution; dissolving a basic polymer with a base group and pK value higher than pH of water; and mixing acidic polymer water solution, basic polymer solution and a capture material.
Abstract translation: 目的：提供水凝胶以根据pH选择性地排放靶材料，并且在没有化学交联剂的情况下制备。 构成：制备水凝胶的方法包括以下步骤：将具有酸性基团的酸性聚合物溶解并且pH值低于水的pH以制备酸性聚合物溶液; 溶解碱性聚合物，pK值高于pH值; 并混合酸性聚合物水溶液，碱性聚合物溶液和捕获材料。
-
公开(公告)号：KR1020130089499A
公开(公告)日：2013-08-12
申请号：KR1020120010920
申请日：2012-02-02
Applicant: 강원대학교산학협력단
IPC: A61K9/16 , A61K8/97 , A61K36/704 , A61Q7/00
CPC classification number: A61K9/5123 , A61K9/5192 , A61K36/14 , A61K36/70 , A61K47/542 , A61K47/6901
Abstract: PURPOSE: Cubic phase nanoparticles for enhancing hair growth are provided to concurrently include a water-soluble component and a fat-soluble component, interact with skin lipid and penetrate stratum corneum, thereby maximizing the hair growth promoting efficacy of herbal extracts. CONSTITUTION: Cubic phase nanoparticles for enhancing hair growth are manufactured by including at least one herbal extract which is selected from a group consisting of biota seed extracts, polygonum multiflorum extracts and espinosilla extracts in the water channels of monoolein cubic phase nano particles. A manufacturing method of the cubic phase nanoparticles for enhancing hair growth comprises a step of manufacturing monoolein cubic phase by adding water phase into molten monoolein; a step of manufacturing cubic phase nanoparticles by homogenizing the monoolein cubic phase after the monoolein cubic phase is added in the water phase in which dispersing agents are dissolved; and a step of stirring the cubic phase nanoparticles and at least one extract selected from a group consisting of biota seed extracts, polygonum multiflorum extracts and espinosilla extracts after mixing the cubic phase nanoparticles and the extracts.
Abstract translation: 目的：提供用于增强毛发生长的立方相纳米颗粒，以同时包含水溶性成分和脂溶性成分，与皮肤脂质相互作用并穿透角质层，从而最大限度地提高促进草药提取物的功效。 构成：用于增强毛发生长的立方相纳米颗粒通过在单油酸酯立方相纳米颗粒的水通道中包含至少一种草本提取物来制造，所述至少一种草药提取物选自由生物种子提取物，多孔提取物和西洋参提取物组成的组。 用于增强头发生长的立方相纳米颗粒的制造方法包括通过将水相加入到熔融单油酸酯中来制备单油酸酯立方相的步骤; 在溶解有分散剂的水相中加入单油酯立方相后，通过均化单油酸酯立方相来制造立方相纳米粒子的步骤; 以及在混合立方相纳米颗粒和提取物之后搅拌立方相纳米颗粒和至少一种选自由生物种子提取物，多孔提取物和多西紫露提取物组成的组的提取物的步骤。
-
7.发明公开
公开(公告)号：KR1020130088461A
公开(公告)日：2013-08-08
申请号：KR1020120009703
申请日：2012-01-31
Applicant: 강원대학교산학협력단
CPC classification number: A61K9/1652 , A61K9/1617 , A61K9/1641 , A61K9/1682 , A61K41/0042
Abstract: PURPOSE: A photo-responsive interpenetrating bead is provided to lower crosslink density by photodegradation of a part of photo-crosslinked soluble polymer-coumarin, thereby controlling the release of a target material by photo-irradiation. CONSTITUTION: A photo-responsive interpenetrating bead is composed of alginate and a polymer-coumarin conjugate and has an interpenetrating crosslinked structure. A method for manufacturing the bead comprises the steps of: preparing a polymer-coumarin conjugate; dissolving the polymer-coumarin conjugate with alginate in an aqueous phase to prepare a mixture solution; and irradiating a polyvalent cationic solution by UV ray with a wavelength of 365 nm or greater and dropping the mixture solution to prepare the interpenetrating bead.
Abstract translation: 目的：通过光交联可溶性聚合物 - 香豆素的一部分的光降解来提供光响应互穿珠以降低交联密度，从而通过光照照射来控制靶材料的释放。 构成：光响应互穿珠由藻酸盐和聚合物 - 香豆素缀合物组成，并具有互穿交联结构。 制备珠粒的方法包括以下步骤：制备聚合物 - 香豆素缀合物; 将聚合物 - 香豆素缀合物与藻酸盐溶解在水相中以制备混合物溶液; 并用波长365nm以上的紫外线照射多价阳离子溶液，滴加混合溶液，制备互穿珠粒。
-
公开(公告)号：KR101367386B1
公开(公告)日：2014-02-25
申请号：KR1020120009703
申请日：2012-01-31
Applicant: 강원대학교산학협력단
Abstract: 본 발명은 알지네이트와 고분자-쿠마린 결합체로 이루어지고, 상호침투성 가교구조를 가지며, 광 조사에 의하여 목적물질의 방출을 제어할 수 있는 광 반응성 상호침투 비드(Photo-responsive interpenetrating beads) 및 그 제조방법을 개시한다.
-
公开(公告)号：KR101114538B1
公开(公告)日：2012-02-27
申请号：KR1020090060753
申请日：2009-07-03
Applicant: 강원대학교산학협력단
Abstract: 본 발명은 중심부인 코어와 그를 둘러싸는 벽제로 구성되는 마이크로 캡슐에 있어서,이소프로필아크릴아미드-메타크릴산의 공중합체 및 포집대상 물질을 마이크로 캡슐의 코어로 하고, 온도 및 pH의 변화에 의해 상전이가 나타나지 않는 비민감성 고분자를 코어를 둘러싸는 벽제로 하는 것을 특징으로 하는 마이크로 캡슐 및 그의 제조방법에 관한 것으로, 폴리이소프로필아크릴아미드-메타크릴산 중합체의 상전이 온도(LCST)보다 낮은 온도에서 목적 물질을 비교적 많이 방출하고 높은 온도에서 목적물질을 비교적 적게 방출하는 특징을 나타내고 pH에서 목적 물질을 비교적 적게 방출하고 높은 pH에서 목적물질을 비교적 많이 방출하는 특징을 나타내기 때문에 온도 및 pH 변화에 따라 방출하는 목적물질의 양을 조절할 수 있는바, 내부에 포집된 항암제, 항생제, 항진균제, 항박테리아제, 항산화제, 미백제, 소염제 등의 다양한 소수성, 친수성 생리활성 성분을 필요한 상황에 따라 선택적으로 외부에 방출시킬 수 있는 효과를 발휘한다.
마이크로 캡슐, 메타크릴산, 상전이, 폴리이소프로필아크릴아미드, pH
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.021 seconds)
