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公开(公告)号：KR102246930B1
公开(公告)日：2021-04-30
申请号：KR1020190135118
申请日：2019-10-29
Applicant: 강원대학교산학협력단 , 주식회사 뉴랜드올네이처
IPC: A61K8/9789 , A61K8/98 , A61Q19/00 , A61Q19/08 , A61Q19/02
Abstract: 본발명은상백피및 호장근의복합추출물과마누카꿀을포함하는화장료조성물을제공한다. 본발명의상백피및 호장근의복합추출물과마누카꿀을포함하는조성물은기능성화장품분야에서멜라닌생성및 피부착색을감소시키고, 엘라스타제에의한엘라스틴분해및 주름을억제하는효과를갖는기능성소재로서유용하게사용될수 있다.
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公开(公告)号：KR1020140000540A
公开(公告)日：2014-01-03
申请号：KR1020120067809
申请日：2012-06-25
Applicant: 강원대학교산학협력단
CPC classification number: Y02C10/08
Abstract: The present invention relates to a method for reducing carbon dioxide from soil using biochar derived from corn residue and, more specifically, to a method for reducing carbon dioxide (CO2) from soil by adding biochar to soil which is derived from corn residue which is obtained by thermally decomposing the corn residue at 300-700°C for 1-5 hours. The present invention adds biochar to soil derived from the corn residue which is manufactured by thermally decomposing the corn residue at 300-700°C for 1-5 hours and reduces carbon dioxide generated from soils to atmosphere in order to reduce generation of carbon dioxide which is greenhouse gas and to contribute to prevention of global warming. Also, the biochar derived from the corn residue effectively works on soil quality improvement and contributes to increase of agricultural productivity by not only reducing carbon dioxide but stabilizing soil as a soil organic matter so that the present invention can be industrially used. [Reference numerals] (AA) Untreated; (BB) Biochar; (CC) Corn residue
Abstract translation: 本发明涉及使用源自玉米渣的生物炭来减少土壤二氧化碳的方法，更具体地说，涉及一种从土壤中还原二氧化碳（CO2）的方法，该方法是从获得的玉米渣中的土壤中加入生物炭 通过将玉米残渣在300-700℃下热分解1-5小时。 本发明将来自玉米残渣的土壤添加到生物炭中，该土壤是通过在300-700℃下热分解玉米残渣1-5小时而制造的，并将从土壤产生的二氧化碳减少至大气，以减少二氧化碳的产生， 是温室气体，有助于预防全球变暖。 此外，源自玉米残渣的生物炭有效地改善了土壤质量，并且通过不仅减少二氧化碳而且使作为土壤有机物质的土壤稳定，从而有助于提高农业生产力，从而本发明可以在工业上使用。 （标号）（AA）未处理; （BB）生物炭; （CC）玉米残渣
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公开(公告)号：KR101333110B1
公开(公告)日：2013-11-27
申请号：KR1020110117129
申请日：2011-11-10
Applicant: 강원대학교산학협력단
Abstract: 본 발명은 단백질 활성도 및 상호작용의 동시 측정방법에 관한 것으로, 더욱 구체적으로 타겟 효소 단백질과 기질단백질 사이의 효소 활성도 및 단백질 상호작용을 서로 다른 두 종류의 형광물질을 표지함으로써 동시에 측정할 수 있는 신규한 방법에 관한 것이다. 본 발명에 따르면, 타겟 효소 단백질과 기질단백질 사이의 활성도 및 상호작용은 형광물질로 표지된 효소 및 단백질 어레이를 이용하여 동시에 분석될 수 있다.
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公开(公告)号：KR101808391B1
公开(公告)日：2017-12-12
申请号：KR1020150190588
申请日：2015-12-31
Applicant: 강원대학교산학협력단
IPC: C12Q1/32 , C12N9/04 , C12N9/02 , G01N21/64 , C07D265/38
Abstract: 본발명은 G6PD의활성도측정용조성물, 이를포함하는키트및 G6PD의활성도측정방법에관한것이다.
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公开(公告)号：KR102083220B1
公开(公告)日：2020-03-02
申请号：KR1020190124638
申请日：2019-10-08
Applicant: 강원대학교산학협력단
IPC: C07D471/14 , A61K31/5517 , A61P25/00
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Patent Agency Ranking
公开(公告)号：KR1020170079719A
公开(公告)日：2017-07-10
申请号：KR1020150190588
申请日：2015-12-31
Applicant: 강원대학교산학협력단
IPC: C12Q1/32 , C12N9/04 , C12N9/02 , G01N21/64 , C07D265/38
Abstract: 본발명은 G6PD의활성도측정용조성물, 이를포함하는키트및 G6PD의활성도측정방법에관한것이다.
Abstract translation: 本发明涉及一种用于测量含G6PD组合物的活性，在此测得的G6PD活性的试剂盒和方法。
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7.发明公开
公开(公告)号：KR1020140067642A
公开(公告)日：2014-06-05
申请号：KR1020120135155
申请日：2012-11-27
Applicant: 강원대학교산학협력단
CPC classification number: C02F1/58 , C02F9/00 , C02F2201/002
Abstract: The present invention relates to a method for purifying veterinary antibiotics in water using a biochar derived from burcucumber (Sicyos Angulatus L.) and, more specifically, to a method for manufacturing biochar using burcucumber (Sicyos Angulatus L.) and treating the biochar in a water body containing veterinary antibiotics to purify the veterinary antibiotics in water.
Abstract translation: 本发明涉及一种使用来自牛膝（Sicyos Angulatus L.）的生物炭纯化水中的兽用抗生素的方法，更具体地说，涉及一种使用山核桃（Sicyos Angulatus L.）制造生物炭的方法，并且在 含有兽用抗生素的水体，用于净化水中的兽药抗生素。
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公开(公告)号：KR1020100105254A
公开(公告)日：2010-09-29
申请号：KR1020090024188
申请日：2009-03-20
Applicant: 강원대학교산학협력단
IPC: G01N33/573 , G01N33/68 , G01N33/533
Abstract: PURPOSE: A protein chip for measuring MMP activation, in which a protein is fixed on a solid substrate and a method for measuring MMP activation using the same are provided. CONSTITUTION: A method for measuring MMP(matrix metalloproteinase) activation comprises: a step of preparing the protein chip; a step of contacting a sample containing MMP with the array chip; and a step of confirming substrate amount of decomposed MMP by SPR signal measurement to measure MMP activation. The MMP is selected from MMP-1 to MMP-23. The sample additionally contains Brij-35, Ca2^+ and Zn^2+. The MMP substrate is gelatin, proteoglycan, fibronectin, laminin, or elastin. The SPR signal measurement is performed using SPR biosensor or SPR(surface plasmon resonance imaging).
Abstract translation: 目的：提供一种用于测量MMP活化的蛋白质芯片，其中蛋白质固定在固体底物上，并提供了使用其测定MMP活化的方法。 构成：测量MMP（基质金属蛋白酶）活化的方法包括：制备蛋白质芯片的步骤; 将含有MMP的样品与阵列芯片接触的步骤; 以及通过SPR信号测定来确认分解的MMP的底物量以测量MMP活化的步骤。 MMP选自MMP-1至MMP-23。 样品另外含有Brij-35，Ca2 +和Zn2 +。 MMP底物是明胶，蛋白聚糖，纤连蛋白，层粘连蛋白或弹性蛋白。 使用SPR生物传感器或SPR（表面等离子体共振成像）进行SPR信号测量。
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公开(公告)号：KR100784463B1
公开(公告)日：2007-12-11
申请号：KR1020060136899
申请日：2006-12-28
Applicant: 강원대학교산학협력단
Abstract: A method for preparing a protein chip is provided to reduce the preparation time of the protein chip significantly, be easy to analyze a protein at low concentration by increasing the binding affinity between proteins through modification of a medium and analyze a plurality of proteins simultaneously by maintaining the hydrophobicity of a free portion of the protein chip. A method for preparing a protein chip comprises the steps of: (a) putting a metal chip obtained by depositing the surface of a glass substrate with gold in a reaction solution including a thiol compound having a terminal acid group to fix the thiol compound on the surface of the metal chip; (b) introducing the diamine compound into the acid group terminal of the thiol compound by reacting the thiol compound-fixed metal chip with a diamine compound such as ethylenediamine, hydrazine, 1,3-diaminopropane and putrescine to prepare a raw material; (c) reacting carboxymethyl-dextran with N-hydroxysuccinimide in the presence of carbodiimide by the following reaction formula(1) to prepare N-hydroxysuccinimide-dextran as a protein reception medium; and (d) reacting the prepared raw material with the protein receptor medium to form an amide-linked N-hydroxysuccinimide-dextran(AL NHS-dextran) at an amine group terminal of the raw material. In the reaction formula(1), n is an integer of at least 1. A protein chip prepared by the method comprises: a raw material prepared by introducing a diamine compound to a terminal(-OH) of an acid group of a thiol compound having the acid group at the terminal fixed on the metal chip; and N-hydroxysuccinimide dextran which is an amide-linked protein reception medium.
Abstract translation: 提供了制备蛋白质芯片的方法，以显着减少蛋白质芯片的制备时间，易于通过增加培养基的蛋白质之间的结合亲和力而分析低浓度的蛋白质，并通过维持同时分析多种蛋白质 蛋白质芯片的游离部分的疏水性。 一种制备蛋白质芯片的方法，包括以下步骤：（a）将金属片放入玻璃基片表面，用金填充在含有末端酸基团的硫醇化合物的反应溶液中，将硫醇化合物固定在 金属片表面; （b）通过硫醇化合物固定金属芯片与二胺化合物如乙二胺，肼，1,3-二氨基丙烷和腐胺反应，将二胺化合物引入硫醇化合物的酸基末端以制备原料; （c）通过以下反应式（1）在碳二亚胺的存在下使羧甲基葡聚糖与N-羟基琥珀酰亚胺反应，制备N-羟基琥珀酰亚胺 - 葡聚糖作为蛋白质接收介质; 和（d）使所制备的原料与蛋白质受体培养基反应，以在原料的胺基末端形成酰胺键合的N-羟基琥珀酰亚胺 - 葡聚糖（AL NHS-葡聚糖）。 在反应式（1）中，n为至少为1的整数。通过该方法制备的蛋白质芯片包括：通过将二胺化合物引入硫醇化合物的酸基的末端（-OH）而制备的原料 端子上的酸基固定在金属芯片上; 和N-羟基琥珀酰亚胺葡聚糖，其是酰胺键的蛋白质接收介质。
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公开(公告)号：KR101428553B1
公开(公告)日：2014-08-11
申请号：KR1020120135155
申请日：2012-11-27
Applicant: 강원대학교산학협력단
Abstract: 본 발명은 가시박에서 유래한 바이오차(biochar)를 이용한 수중의 축산용 항생물질의 정화방법에 관한 것으로서 보다 상세하게는 가시박을 이용하여 바이오차를 제조하고, 상기 가시박 유래 바이오차를 축산용 항생물질이 함유된 수중에 처리하여 수중의 축산용 항생물질을 정화하는 방법에 관한 것이다.
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