탄소 나노물질을 포함하는 암세포 증식 억제용 조성물
    3.
    发明授权
    탄소 나노물질을 포함하는 암세포 증식 억제용 조성물 有权
    包含用于抑制肿瘤细胞增殖的碳纳米材料的组合物

    公开(公告)号:KR101153799B1

    公开(公告)日:2012-06-13

    申请号:KR1020100015987

    申请日:2010-02-23

    Abstract: 본 발명은 탄소 나노물질을 유효성분으로 포함하는 암세포 증식 억제용 조성물에 관한 것이다. 보다 구체적으로, 본 발명의 탄소 나노 물질은 분화가 끝나서 증식을 하지 않는 뇌신경세포에는 영향을 미치지 않으면서 뇌종양 세포에 특이적으로 증식을 억제할 수 있는 조성물에 관한 것이다. 암세포의 증식과 이동을 억제하여, 암세포 전이를 막을 수 있으며, 다른 항암제와 병용 사용하여, 암 질환을 예방하고 치료할 수 있다.

    생체 내 면역독성 감소를 위한 고분산 탄소나노튜브의 제조방법
    4.
    发明公开
    생체 내 면역독성 감소를 위한 고분산 탄소나노튜브의 제조방법 无效
    制备用于降低免疫细胞毒性的高分散碳纳米管的方法

    公开(公告)号:KR1020120043352A

    公开(公告)日:2012-05-04

    申请号:KR1020100104611

    申请日:2010-10-26

    Abstract: PURPOSE: A manufacturing method of high-dispersed carbon nanotube for reducing in vivo immune toxicity is provided to enhance dispersibility by performing and repeating ultrasonication. CONSTITUTION: A manufacturing method of high-dispersed carbon nanotube for reducing in vivo immune toxicity comprises next steps: a first step of mixing carbon nanotube in a strong acid solvent in order to introduce a functional group containing oxygen to surface of the carbon nanotube; a second step of carbon nanotube ultrasonication in the solvent; and repeating the first and the second step successively. The strong acid solvent is sulfuric acid, nitric acid, or a mixture thereof. The first step comprises the next step: stirring carbon nanotube in a mixture which has 3:1 ratio of sulfuric acid to nitric acid with a speed of 250-320 RPM for 15-45 minutes.

    Abstract translation: 目的:提供用于降低体内免疫毒性的高分散碳纳米管的制造方法,以通过执行和重复超声波处理来提高分散性。 构成:用于降低体内免疫毒性的高分散碳纳米管的制造方法包括以下步骤:将碳纳米管在强酸溶剂中混合以将含氧官能团引入到碳纳米管的表面的第一步骤; 在溶剂中碳纳米管超声波处理的第二步; 并连续重复第一和第二步骤。 强酸溶剂是硫酸,硝酸或它们的混合物。 第一步包括下一步骤:以250-320RPM的速度将硫酸与硝酸的比例为3:1的混合物中的碳纳米管搅拌15-45分钟。

    암세포의 내성을 억제한 탄소나노튜브 기반 항암제
    7.
    发明公开
    암세포의 내성을 억제한 탄소나노튜브 기반 항암제 有权
    使用碳纳米管的非破坏剂反应剂代理

    公开(公告)号:KR1020140026895A

    公开(公告)日:2014-03-06

    申请号:KR1020120092644

    申请日:2012-08-23

    Abstract: Provided in the present invention is an anticancer compound including multi-layered carbon nanotubes, and an anticancer agent bonded to the surface of the carbon nanotubes in a covalent bond, in order to provide an anticancer agent capable of overcoming cancer cell resistance. The anticancer compound of the present invention includes multi-layered carbon nanotubes, and an anticancer agent bonded to the surface of the carbon nanotubes in a covalent bond. The multi-layered carbon nanotubes have a diameter ranging from 5-50 nm, and a length ranging from 100-350 nm. The surface of the carbon nanotubes is reformed to have 10-35% of carboxyl groups.

    Abstract translation: 本发明中提供了包含多层碳纳米管的抗癌化合物和与碳纳米管表面共价键结合的抗癌剂,以提供能够克服癌细胞耐药性的抗癌剂。 本发明的抗癌化合物包括多层碳纳米管和以共价键结合到碳纳米管表面的抗癌剂。 多层碳纳米管的直径范围为5-50nm,长度范围为100-350nm。 将碳纳米管的表面重整成具有10-35%的羧基。

    독성을 억제하는 타이타늄 나노 구조 스텐트의 제작방법
    10.
    发明公开
    독성을 억제하는 타이타늄 나노 구조 스텐트의 제작방법 有权
    制造纳米结构性STENT抑制性毒性的方法

    公开(公告)号:KR1020110129596A

    公开(公告)日:2011-12-02

    申请号:KR1020100049070

    申请日:2010-05-26

    CPC classification number: A61L31/082 A61F2/82 B82B3/0009 C23C14/14

    Abstract: PURPOSE: A manufacturing method of a titanium nano-structure stent is provided to prevent vascular restenosis by suppressing the toxicity reaction of macrophage. CONSTITUTION: A manufacturing method of a titanium nano-structure stent comprises: a step of vaporizing titanium on the surface of a sample by using an electron-beam evaporator; and a step of forming a nano structure on the titanium surface by enhancing deposition speed. In the deposition step, the electron beam current density is 165-175 mA/cm^2.

    Abstract translation: 目的:提供钛纳米结构支架的制造方法,通过抑制巨噬细胞的毒性反应来预防血管再狭窄。 构成:钛纳米结构支架的制造方法包括:通过使用电子束蒸发器在样品的表面上蒸发钛的步骤; 以及通过提高沉积速度在钛表面上形成纳米结构的步骤。 在沉积步骤中,电子束电流密度为165-175mA / cm 2。

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