Abstract:
본 발명은 검정콩 추출물을 포함하는 퇴행성 뇌신경 질환 치료 또는 예방용 조성물에 관한 것으로, 보다 구체적으로는 15 내지 25 중량%의 델피니딘-3-글루코사이드, 65 내지 80 중량%의 시아니딘-3-글루코사이드 및 5 내지 10중량 %의 폐튜니딘-3-글루코사이드를 포함하는 검정콩 추출물 또는 이의 분획물을 포함하는 퇴행성 뇌신경 질환의 예방 또는 치료용 조성물, 상기 검정콩 추출물 또는 이의 분획물을 포함하는 두뇌 또는 인지 기능의 증진을 위한 기능성 식품 조성물, 및 상기 조성물을 제조하는 방법에 관한 것이다.
Abstract:
PURPOSE: A pharmaceutical composition containing anthocyanine isolated from black soybean shells for preventing diabetes is provided to prevent and treat diabetes and related complications without toxic effects. CONSTITUTION: A pharmaceutical composition for preventing or treating diabetes contains anthocyanine isolated from black soybean shells. Anthocyanine contains 65-80 weight% of cyaniding-3-glucoside, 15-25 weight% of delphinidin-3-glucoside and 5-10 weight% of petunidin-3-glucoside. The pharmaceutical composition is used in the form of a capsule, tablet, chewing tablet, powder, dry syrup, granule, soft capsule, pill, and drink.
Abstract:
PURPOSE: A composition containing anthocyanin isolated from Vitis coignetiae Pulliat for treating liver cancer is provided to induce and strengthen apoptosis of hepatocytes and ensure anti-proliferation and anti-infiltration to liver cancer cells. CONSTITUTION: A composition for preventing and treating liver cancer contains anthocyanin isolated from Vitis coignetiae Pulliat as an active ingredient. A method for isolating the anthocyanin comprises: a step of extracting Vitis coignetiae Pulliat with methanol containing 0.1% of HCl at 5°C for 24 hours; a step of compress-concentrating the Vitis coignetiae Pulliat extract and washing the extract on Ambrite XAD-7 adsorber with water and ethyl acetate; and a step of eluting methanol solution having 1% of HCl to obtain the anthocyanin. The anthocyanin is delphinidin-3,5-diglucoside and cyanidin-3,5-diglucoside.
Abstract:
본 발명은 검정콩부터 추출된 안토시아닌을 유효성분으로 함유하는 당뇨 예방용 약학조성물로 보다 상세하게는 검정콩 껍질로부터 추출된 안토시아닌을 유효성분으로 함유하는 체내 글루코스(glucose)의 감소 또는 췌장세포의 자멸사 억제에 의한 당뇨 예방용 약학조성물 및 당뇨 예방용 건강 또는 건강보조 식품으로, 본 발명에 따른 조성물은 당뇨유발 및 당뇨합병증의 예방 및 치료효과가 매우 우수할 뿐만 아니라 독성이 없으므로 식품의 형태로 섭취할 수 있어 장기적으로 일상생활의 식이 및 생활습관을 통하여 당뇨 및 당뇨 합병증을 예방 할 수 있으며 당뇨 치료제로서 유용하게 상용될 수 있다. 검정콩, 안토시아닌, 당뇨, 글루코스, 췌장세포
Abstract:
A pharmaceutical composition comprising anthocyanin is provided to show excellent effect on wound healing, thereby being usefully used as an excellent wound healing agent. A pharmaceutical composition for healing wound comprises anthocyanin, which is extracted from black soybean shell and consists of cyanidin-3-glucoside, delphinidin-3-glucoside and petunidin-3-glucoside, as an effective ingredient, and is in the form of ointment, ointment patch, gel, liquid medicine, cataplasma, tape, aerosol, powder or dressing product.
Abstract:
PURPOSE: A capsule formulation containing an independent levocetirizine layer for preventing or treating allergic rhinitis and asthma is provided to ensure excellent product stability and to maximize treatment effect. CONSTITUTION: A capsule formulation for preventing or treating allergic rhinitis comprises: an independent layer containing montelukast or a pharmaceutically acceptable salt thereof; and an independent layer containing levocetirizine or a pharmaceutically acceptable salt thereof. The independent layers are formed in granules or a tablet. The independent layers are prepared without water or an organic solvent or the independent layers substantially do not contain water or the organic solvent. The table has a coating layer. A coating base for the coating layer is methyl cellulose, ethyl cellulose, polyvinyl alcohol, polyvinyl pyrrolidone, hydroxyl ethyl cellulose, hydroxylpropyl methyl cellulose, or a mixture thereof. The capsule is a soft capsule.
Abstract:
본 발명은 검정콩 추출물을 포함하는 퇴행성 뇌신경 질환 치료 또는 예방용 조성물에 관한 것으로, 보다 구체적으로는 15 내지 25 중량%의 델피니딘-3-글루코사이드, 65 내지 80 중량%의 시아니딘-3-글루코사이드 및 5 내지 10중량 %의 폐튜니딘-3-글루코사이드를 포함하는 검정콩 추출물 또는 이의 분획물을 포함하는 퇴행성 뇌신경 질환의 예방 또는 치료용 조성물, 상기 검정콩 추출물 또는 이의 분획물을 포함하는 두뇌 또는 인지 기능의 증진을 위한 기능성 식품 조성물, 및 상기 조성물을 제조하는 방법에 관한 것이다.
Abstract:
PURPOSE: A composition containing black bean extract for preventing or treating neurodegenerative diseases is provided to protect and regenerate nerves. CONSTITUTION: A composition or for preventing or treating neurodegenerative diseases contains 15-25 wt% of delphinidin-3-glucoside, 65-80 wt% of cyanidine-3-glucoside, and 5-10 wt% of petunidin-3-glucoside. The composition additionally contains pharmaceutically acceptable carriers. A functional food composition for enhancing brain or cognitive function contains 15-25 wt% of delphinidin-3-glucoside, 65-80 wt% of cyanidine-3-glucoside, and 5-10 wt% of petunidin-3-glucoside. A method for manufacturing the composition comprises: a step of extracting black soybeans with water, organic solvent, or a mixture thereof to prepare black soybean extract; a step of fractioning the extract using water or a non-polar organic solvent; and a step of isolating and purifying delphinidin-3-glucoside, cyanidine-3-glucoside, and cyanidine-3-glucoside from the fraction.