公开(公告)号：KR1020100070514A

公开(公告)日：2010-06-28

申请号：KR1020080129091

申请日：2008-12-18

Applicant: 대구한의대학교산학협력단

Inventor： 장정희 ,  제갈경환 ,  박성준 ,  김창열 ,  이찬 ,  양재하

IPC: A61K36/076 ,  A61P25/28

Abstract: PURPOSE: A composition containing Poria cocos dry powder and extract thereof is provided to enhance memory and Hippocampus the choline acetyltransferase expression. CONSTITUTION: A composition for preventing and treating memory loss and memory disorder contains Poria cocos dry powder and extract thereof as an active ingredient. The Poria cocos extract is obtained by water, low alcohol of C1-C4, or mixture solvent. The memory disorder is retention defect related disease Alzheimer disease, dementia by intracerbroventricular dementia or head injury.

Abstract translation: 目的：提供含有茯苓干粉及其提取物的组合物，以增强记忆力和海马胆碱乙酰转移酶的表达。 构成：用于预防和治疗记忆丧失和记忆障碍的组合物含有茯苓干粉及其提取物作为活性成分。 茯苓提取物是通过水，C1-C4的低级醇或混合溶剂获得的。 记忆障碍是保留缺陷相关疾病阿尔茨海默病，脑室内痴呆或头部损伤引起的痴呆。

公开(公告)号：KR101072662B1

公开(公告)日：2011-10-11

申请号：KR1020080129091

申请日：2008-12-18

Applicant: 대구한의대학교산학협력단

Inventor： 장정희 ,  제갈경환 ,  박성준 ,  김창열 ,  이찬 ,  양재하

IPC: A61K36/076 ,  A61P25/28

Abstract: 본발명은복신(Poria cocos) 건조분말또는그 추출물을유효성분으로함유하는건망증및 기억력장애관련질환의예방및 치료를위한조성물에관한것으로, 상세하게는본 발명의복신건조분말또는그 추출물이스코폴라민에의해기억력손상이유발된동물모델에서물미로실험(Morris water-maze test) 및 Y-미로실험(Y-maze test)을통하여기억력증진효과를나타내고, 베타아밀로이드로유도된신경세포독성을억제하며, 해마내 아세틸콜린합성효소및 무스카린성아세틸콜린수용체의발현을증가시킴을확인함으로써, 상기조성물은건망증및 기억력장애관련질환의예방및 치료에유용한약학조성물및 건강기능식품에이용될수 있다.