Abstract:
PURPOSE: A composition Angelica utilis makino extract is provided to suppress acetylcholine esterase, to improve learning ability, and to treat neurodegenerative diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating neurodegenerative diseases contains Angelica utilis makino extract as an active ingredient. The Angelica utilis makino extract is a crude extract, non-polar solvent soluble extract, or polar solvent soluble extract. The crude extract is isolates using water, methanol, ethanol, butanol, or mixture solvent thereof. A health food for preventing and treating neurodegenerative diseases contains Angelica utilis makino extract as an active ingredient. The health food is manufactured in the form of powder, granule, tablet, capsule, or beverage.
Abstract:
본 발명은 프로폴리스 추출물 또는 이로부터 분리된 크리신 화합물을 유효성분으로 함유하는 조성물에 관한 것으로서, 구체적으로 본 발명의 프로폴리스 추출물 또는 이로부터 분리된 크리신 화합물은 정신흥분제(psychomotor stimulants)의 강화작용(reinforcing effect)을 연구하기에 매우 적합한 행동적 실험기법인 자가투여(self-administration) 실험에서 코카인 자가 섭취량을 농도 의존적으로 감소시키고 이는 음식섭취(food test)를 통한 음식보상효과(food reinforcing effect)에는 영향이 없음을 확인함으로써, 상기 조성물은 코카인 중독 및 금단증상의 예방 및 치료를 위한 약학조성물 및 건강기능식품으로 유용하게 이용될 수 있다.
Abstract:
The present invention relates to a composition for preventing and treating alcohol intoxication and withdrawal symptoms, which contains an extract of propolis or chrysin isolated therefrom as an active ingredient. Specifically, the extract of propolis or chrysin isolated therefrom of the present invention dose dependently decreases a self intake amount of alcohol in a self-administration experiment, which is a behavioral experiment technique suitable for researching behavioral measurement related to drug-taking and drug-seeking. By ascertaining the fact that the above characteristic has no influence on a sucrose reinforcing effect when experimenting sucrose self-taking through a 20% sucrose solution intake to check whether or not the above characteristic influences a natural reinforcing effect, the composition can be used as a pharmaceutical composition and a health supplement for preventing and treating alcohol intoxication and withdrawal symptoms.
Abstract:
본 발명은 미나리과에 속하는 명일엽 ( Angelica keiskei )의 전초인 신선초의 추출물을 유효성분으로 함유하는 건망증 개선 및 퇴행성 뇌질환 치료용 약학 조성물 또는 건강 기능 식품에 관한 것으로서, 상기 추출물은 아세틸콜린에스테라아제의 저해능을 나타내며, 스코폴라민에 의해 유도된 기억력 감퇴 동물군의 학습증진 및 공간지각능력을 높은 수준으로 향상시키는 탁월한 효능을 나타내므로 건망증 개선 및 퇴행성 뇌질환 치료에 유용한 약학 조성물 또는 건강 기능 식품을 제공한다. 신선초, 추출물, 건망증, 퇴행성 뇌질환, 아세틸콜린에스테라아제
Abstract:
The present invention relates to a composition that contains an extract of propolis or chrysin isolated therefrom as an active ingredient. Specifically, the extract of propolis or chrysin isolated therefrom of the present invention dose dependently decreases a self intake amount of cocaine in a self-administration experiment, which is a behavioral experiment technique suitable for researching reinforcing effects of psychomotor stimulants. By checking the fact that the above characteristic exerts no influence on a food reinforcing effect through a food test, the composition can be used as a pharmaceutical composition and a health supplement for preventing and treating cocaine intoxication and withdrawal symptoms.