디옥시니발레놀 생체특이단백질 햅토글로빈을 이용한디옥시니발레놀 중독증·노출 진단방법 및 진단키트
    6.
    发明公开
    디옥시니발레놀 생체특이단백질 햅토글로빈을 이용한디옥시니발레놀 중독증·노출 진단방법 및 진단키트 有权
    使用HAPTOGLOBIN特异性蛋白质和诊断试剂盒检测脱氧十二烯酚的毒性和接触的方法

    公开(公告)号:KR1020070111231A

    公开(公告)日:2007-11-21

    申请号:KR1020060044347

    申请日:2006-05-17

    Abstract: A method and kit for diagnosis of toxicity and exposure for deoxynivalenol are provided to improve detection convenience and time of deoxynivalenol by detecting increase of a haptoglobin level in blood plasma. A method for diagnosis of toxicity and exposure for deoxynivalenol comprises the steps of: coating an ELISA(enzyme-linked immunosorbent assay) plate with an anti-haptoglobin antibody; adding diluted blood plasma into the plate and reacting them for a certain period; reacting the plate with a secondary antibody to determine presence of haptoglobin having the amino acid sequence of SEQ ID NO:1. A kit for diagnosis of toxicity and exposure for deoxynivalenol comprises an antibody specific to haptoglobin or its immunogenic fragment, fixed in a reaction region of a strip.

    Abstract translation: 提供了用于诊断脱氧雪腐镰刀菌烯醇的毒性和暴露的方法和试剂盒,通过检测血浆中触珠蛋白水平的增加来提高脱氧雪腐镰刀菌烯醇的检测方便性和时间。 用于诊断脱氧雪腐镰刀菌烯醇的毒性和暴露的方法包括以下步骤:用抗 - 触珠蛋白抗体包被ELISA(酶联免疫吸附测定)板; 将稀释的血浆加入板中并使其反应一定时间; 使该板与第二抗体反应以确定具有SEQ ID NO:1的氨基酸序列的触珠蛋白的存在。 用于诊断毒性的试剂盒和脱氧雪腐镰刀菌烯醇的暴露包括固定在条带的反应区域中对触珠蛋白或其免疫原性片段特异的抗体。

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