닭의 괴사성 장염을 예방하는 백신 조성물
    3.
    发明公开
    닭의 괴사성 장염을 예방하는 백신 조성물 有权
    用于预防鸡肉中的肠道炎症的疫苗组合物

    公开(公告)号:KR1020130055049A

    公开(公告)日:2013-05-28

    申请号:KR1020110119490

    申请日:2011-11-16

    Abstract: PURPOSE: A vaccine including recombinant Clostridium antigen protein, Net-B or PFO, is provided to effectively prevent necrotic enteritis in chicken, to reduce occurrence of necrotic enteritis, to strengthen chicken health, and to reduce economic loss in a farmhouse. CONSTITUTION: A vaccine composition for preventing necrotic enteritis in chicken contains Clostridium perfringens-derived recombinant Clostridium antigen protein, Net-B or PFO. The vaccine composition additionally contains a pharmaceutically acceptable adjuvant. The Clostridium antigen protein is prepared by natural extraction or genetic recombination. The genetic recombination comprises: a step of inserting a nucleic acid sequence encoding the antigen protein into an expression vector; a step of transforming the vector to a host cell and culturing a transformant; and a step of obtaining the antigen protein from the transformant.

    Abstract translation: 目的:提供重组梭状芽胞杆菌抗原蛋白,Net-B或PFO疫苗,有效预防鸡肉坏死性肠炎,减少坏死性肠炎的发生,加强鸡肉健康,减少农村经济损失。 构成:用于预防鸡中坏死性肠炎的疫苗组合物含有产气荚膜梭菌衍生的重组梭状芽胞杆菌抗原蛋白,Net-B或PFO。 疫苗组合物另外含有药学上可接受的佐剂。 通过天然提取或遗传重组制备梭菌属抗原蛋白。 基因重组包括:将编码抗原蛋白的核酸序列插入表达载体的步骤; 将载体转化到宿主细胞并培养转化体的步骤; 以及从转化体获得抗原蛋白的步骤。

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