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    T 세포의 병원체 감염 세포 독성능 평가 방법
    1.
    发明授权
    T 세포의 병원체 감염 세포 독성능 평가 방법 有权
    评估T细胞对病原体感染细胞毒性作用的方法

    公开(公告)号：KR101777256B1

    公开(公告)日：2017-09-12

    申请号：KR1020160086205

    申请日：2016-07-07

    Applicant: 대한민국(농림축산식품부 농림축산검역본부장) ,  베터리너리 메디컬 리서치 앤 디벨롭먼트

    Inventor： 차상호 ,  우인옥 ,  유지은 ,  최은진 ,  송재영 ,  조인수 ,  청원조셉청 ,  아만다린그림

    IPC: G01N33/50

    CPC classification number: G01N33/5014 ,  G01N33/505 ,  G01N33/5055 ,  G01N2333/005 ,  G01N2333/195

    Abstract: 본발명은 T 세포의병원체감염세포독성능평가방법및 세포독성능에관여하는병원체특이적 T 세포의정보제공방법에관한것이다. 본발명의 T 세포의병원체감염세포독성능평가방법은 PRRSV 특이적 T 세포가타겟세포에서감염하여증식하는 PRRSV를인식하여감염세포에독성을유발하여제거하는정도를평가할수 있을뿐만아니라, 상기세포독성기전에관여하는특이적 T 세포의종류에대한기전역학을평가하여이에대한정보를제공하는효과가있다. 또한, T 세포가추출된세포의개체와동일개체(autologous) 혹은동일유전자형을가진다른개체(heterologous)에대한세포독성능을확인할수 있어, 돼지세포면역에관한기초정보및 세포성면역의평가방법을제공할수 있다.

    Abstract translation: 本发明涉及提供参与病原体感染的细胞对接性能评价方法和细胞毒性T细胞表现病原体特异性T细胞的信息的方法。 Ť病原体感染的细胞停靠在本发明的电池的性能评价方法是认识到是PRRSV特异性T细胞的增殖和感染的靶细胞不仅能够评估去除病因毒性感染的细胞，将细胞的程度的PRRSV 评估涉及毒性机制的特定T细胞类型的机制并提供关于它的信息是有效的。 另外，基本信息和与之有关的猪细胞免疫细胞介导的免疫它可以检查细胞毒性性能的其他对象（异源的）与对象，相同的对象（自体）或细胞的同基因型收集的T细胞的评价方法 在可以提供。

    면역유도능이 증가된 돼지생식기호흡기증후군 바이러스
    4.
    发明公开
    면역유도능이 증가된 돼지생식기호흡기증후군 바이러스 有权
    具有增强免疫诱导性质的生殖和呼吸道感染综合征病毒

    公开(公告)号：KR1020140045774A

    公开(公告)日：2014-04-17

    申请号：KR1020120111953

    申请日：2012-10-09

    Applicant: 전북대학교산학협력단 ,  대한민국(농림축산식품부 농림축산검역본부장)

    Inventor： 김원일 ,  최은진 ,  김은주 ,  이창희 ,  송재영

    IPC: C12N7/01 ,  A61K39/12 ,  G01N33/569

    Abstract: The present invention relates to a porcine reproductive and respiratory syndrome virus and a vaccine comprising the same for preventing and treating porcine reproductive and respiratory syndrome. PRRSV according to the present invention which an ORF (open reading frame) 5 or ORF 7 of CB11054 increase a production of a cytokine like TNF-alpha, INF-alpha, INF-beta, and IL-12, to have an excellent effect of inducing an immune response, therefore, has an excellent defense capabilities against PRRSV after vaccination.

    Abstract translation: 本发明涉及一种猪繁殖与呼吸综合征病毒和一种包含其的预防和治疗猪繁殖与呼吸综合征的疫苗。 根据本发明的PR1V，CB11054的ORF（开放阅读框）5或ORF 7增加细胞因子如TNF-α，INF-α，INF-β和IL-12的产生，具有优异的 因此，诱导免疫应答在接种疫苗后对PRRSV具有极好的防御能力。

    유전자칩, 이를 이용한 돼지콜레라 바이러스 또는소바이러스성설사증 바이러스 유전자의 검사방법 및 그를포함하는 진단키트
    8.
    发明公开
    유전자칩, 이를 이용한 돼지콜레라 바이러스 또는소바이러스성설사증 바이러스 유전자의 검사방법 및 그를포함하는 진단키트 有权
    基因芯片，使用基因芯片检测CSFV和BVDV基因的方法以及包含基因芯片的检测试剂盒

    公开(公告)号：KR1020070116377A

    公开(公告)日：2007-12-10

    申请号：KR1020060050345

    申请日：2006-06-05

    Applicant: 대한민국(농림축산식품부 농림축산검역본부장) ,  (주)바이오메트릭스 테크놀로지 ,  주식회사 메디안디노스틱

    Inventor： 송재영 ,  김병한 ,  탁동섭 ,  최은진 ,  임성인 ,  한규하 ,  김태선 ,  송금수 ,  주후돈 ,  장병식 ,  이현정 ,  김준배

    IPC: G01N33/53 ,  G01N33/50 ,  C12Q1/68

    CPC classification number: C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6888 ,  C12Q2521/107 ,  C12Q2531/113 ,  C12Q2537/143 ,  G01N33/5308

    Abstract: A method for detecting swine fever virus or bovine viral diarrhea virus(BVDV) existing in blood or tissue of pig and cow is provided to detect the swine fever virus or BVDV with high specificity and also identify genotypes rapidly and accurately through one testing process. A method for testing swine fever genes using a gene chip comprises the steps of: (a) extracting RNA from swine serum or blood; (b) amplifying the extracted RNA through multiplex reverse transcription-polymerase chain reaction(RT-PCR); (c) hybridizing the amplified swine fever gene with the gene chip; and (d) identifying the specifically coupled swine fever gene through the hybridization and a genotype thereof. A gene chip comprises : at least one forward sequence selected from the group consisting of at least one sequence selected from the group consisting of SEQ ID : NOs. 1-13 and a probe having at least 10-mer sequence homology to the sequences of the SEQ ID : NOs. 1-13; and a reverse sequence of the forward sequence and the probe having at least 10-mer sequence homology to the sequences and is used for identifying the swine fever and BVDV to be positive and identifying the kind and location of the probe used in an oligonucleotide chip for testing genotypes. A method for testing swine fever virus or BVDV comprises a step of testing a swine fever virus gene or a BVDV gene using the gene chip.

    Abstract translation: 本发明提供一种检测猪，牛血液或组织中存在的猪瘟病毒或牛病毒性腹泻病毒（BVDV）的方法，以高特异性检测猪瘟病毒或BVDV，并通过一次检测过程快速，准确地鉴定基因型。 使用基因芯片测试猪瘟基因的方法包括以下步骤：（a）从猪血清或血液中提取RNA; （b）通过多重逆转录聚合酶链反应（RT-PCR）扩增提取的RNA; （c）将扩增的猪瘟基因与基因芯片杂交; 和（d）通过杂交及其基因型鉴定特异性偶联的猪瘟基因。 基因芯片包含：至少一种选自SEQ ID NO： 1-13和与SEQ ID NO：的序列具有至少10-mer序列同源性的探针。 1-13; 以及与序列具有至少10-mer序列同源性的正向序列和探针的反向序列，并用于鉴定猪发热和BVDV为阳性，并鉴定用于寡核苷酸芯片中的探针的种类和位置 测试基因型。 一种用于测试猪瘟病毒或BVDV的方法包括使用该基因芯片测试猪瘟病毒基因或BVDV基因的步骤。

    가축용 주사기
    10.
    发明公开
    가축용 주사기 有权
    LIVESTOCK注射器

    公开(公告)号：KR1020030066038A

    公开(公告)日：2003-08-09

    申请号：KR1020020006191

    申请日：2002-02-04

    Applicant: 주식회사 엠아이텍 ,  대한민국(농림축산식품부 농림축산검역본부장)

    Inventor： 정인권 ,  안동준 ,  박찬승 ,  안성순 ,  송재영 ,  박종현 ,  차상호 ,  최은진 ,  권준헌

    IPC: A61M5/20

    Abstract: PURPOSE: An injector for livestock is provided to improve inoculation efficiency since a continuous inoculation is possible, inoculate precisely on an inoculation region of moving livestock and make maintenance easier due to its simple structure. CONSTITUTION: The injector for livestock comprises: an injector main body(2) which has a pressure handle(H) slidably mounted; a chemical feeding unit which injects a chemical by the operation of the pressure handle(H); and a display unit which is mounted at one side face of the chemical feeding unit and displays whether inoculation is carried out or not.

    Abstract translation: 目的：提供家禽注射器，以提高接种效率，因为连续接种是可能的，准确地接种在移动的牲畜的接种区域，并由于其简单的结构使维护更容易。 构成：用于家畜的注射器包括：具有可滑动安装的压力手柄（H）的喷射器主体（2）; 化学进料单元，其通过所述压力手柄（H）的操作来喷射化学品; 以及显示单元，其安装在所述化学供给单元的一个侧面，并显示是否进行接种。

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