公开(公告)号：KR1020020060176A

公开(公告)日：2002-07-16

申请号：KR1020027003218

申请日：2001-06-19

Applicant: 로레알

Inventor： 오브룅-손느빌오딜 ,  시모네쟝-띠에리

IPC: A61K8/84 ,  A61K8/06

Abstract: 본 발명은, 생리학적 허용가능 매질 내에 폴리올레핀에서 유도된 하나 이상의 올리고머 또는 중합체를 유화제로서 함유하는 유중수 에멀션에 관한 것이다.
사용되는 올리고머 또는 중합체는 바람직하게는 임의로 에스테르화되거나 아미드화된 숙신 말단부를 갖는 폴리올레핀, 또는 상기 폴리올레핀의 염, 특히 에스테르화 또는 아미드화 숙신 말단부를 갖는 폴리이소부틸렌이다.
수득된 에멀션은 높은 비율의 수성상의 존재 하에서도 안정하다. 또한, 이것은 적용시 신선한 느낌을 제공한다. 이것은 특히 화장용, 피부과적 및 약학적 분야, 특히 피부 및/또는 네일 케어용, 피부의 메이크업 제거 및/또는 클렌싱용, 및/또는 피부 메이크업으로서 사용될 수 있다.

公开(公告)号：KR100455005B1

公开(公告)日：2004-11-06

申请号：KR1020027003218

申请日：2001-06-19

Applicant: 로레알

Inventor： 오브룅-손느빌오딜 ,  시모네쟝-띠에리

IPC: A61K8/84 ,  A61K8/06

CPC classification number: A61Q19/00 ,  A61K8/06 ,  A61K8/31 ,  A61K8/8111 ,  A61K8/922 ,  A61Q19/005 ,  A61Q19/007 ,  Y10S514/845 ,  Y10S514/88 ,  Y10S514/937

Abstract: Composition comprising an aqueous phase dispersed in an oil phase includes an emulsifier comprising a polar portion and a nonpolar polyolefin portion of at least 40 carbon atoms.

Abstract translation: 包含分散在油相中的水相的组合物包括乳化剂，其包含极性部分和至少40个碳原子的非极性聚烯烃部分。

公开(公告)号：KR100447672B1

公开(公告)日：2004-09-08

申请号：KR1020010042132

申请日：2001-07-12

Applicant: 로레알

Inventor： 라로레플로렁스 ,  오브룅-손느빌오딜 ,  시모네쟝-띠에리

IPC: A61K7/00

CPC classification number: A61Q19/007 ,  A61K8/062 ,  A61K9/1075 ,  A61K2800/21 ,  A61K2800/262 ,  B01F17/0028 ,  B01F17/0085 ,  B82Y5/00

Abstract: An oil-in-water nanoemulsion (A) with oil globule size below 100 nm comprising at least one amphiphilic non-ionic or anionic lipid and at least one non-ionic hydrosoluble polymer has a weight ratio of oily phase to amphiphilic lipid of 1.2-10. An oil-in-water nanoemulsion (A) with oil globule size below 100 nm comprising at least one amphiphilic non-ionic or anionic lipid and at least one nonionic hydrosoluble polymer (B) has a weight ratio of oily phase to amphiphilic lipid of 1.2-10. (B) is homo- and copolymers of ethylene oxide, of vinylalcohols, of vinylpyrrolidone, of vinylcaprolactam, or of vinylmethylether; homo- and copolymers of neutral acrylics; (1-2C)alkylcelluloses and their derivatives; or (hydroxy)(1-3C)alkylguar. Independent claims are also included for: (1) a cosmetic or dermatological composition comprising (A); (2) an ophthalmic support containing (A); (3) a pharmaceutical composition containing (A); and (4) a process of thickening a nanoemulsion with the hydrosoluble polymers above.

Abstract translation: 包含至少一种两亲性非离子型或阴离子型脂质和至少一种非离子型水溶性聚合物的油滴尺寸小于100nm的水包油纳米乳液（A）具有的油相与两亲脂质的重量比为1.2- 10。 包含至少一种两亲性非离子型或阴离子型脂质和至少一种非离子型水溶性聚合物（B）的油滴尺寸小于100nm的水包油纳米乳液（A）具有1.2的油相与两亲脂质的重量比 -10。 （B）是环氧乙烷，乙烯醇，乙烯基吡咯烷酮，乙烯基己内酰胺或乙烯基甲基醚的均聚物和共聚物; 中性丙烯酸均聚物和共聚物; （1-2C）烷基纤维素及其衍生物; 或（羟基）（1-3C）烷基瓜尔胶。 独立权利要求还包括：（1）化妆品或皮肤病学组合物，其包含（A）; （2）含有（A）的眼科支架; （3）含有（A）的药物组合物; 和（4）用上述水溶性聚合物增稠纳米乳液的方法。

公开(公告)号：KR1020020006606A

公开(公告)日：2002-01-23

申请号：KR1020010042132

申请日：2001-07-12

Applicant: 로레알

Inventor： 라로레플로렁스 ,  오브룅-손느빌오딜 ,  시모네쟝-띠에리

IPC: A61K7/00

CPC classification number: A61Q19/007 ,  A61K8/062 ,  A61K9/1075 ,  A61K2800/21 ,  A61K2800/262 ,  B01F17/0028 ,  B01F17/0085 ,  B82Y5/00

Abstract: PURPOSE: Provided is an oil-in-water nanoemulsion including an oily phase which is dispersed in an aqueous phase and includes oil globules having a number-average size of less than 100nm. Therefore, the nanoemulsion obtained is preferably transparent and stable on storage and may form a composition for topical, preferably cosmetic or dermatological compositions, pharmaceutical compositions and ophthalmological compositions. CONSTITUTION: This nanoemulsion comprises: (i) at least one amphiphilic lipid selected from the group including nonionic amphiphilic lipids and anionic amphiphilic lipids; and (ii) at least one water-soluble nonionic polymer selected from the group including homopolymers and copolymers of ethylene oxide; polyvinyl alcohols; homopolymers and copolymers of vinylpyrrolidone; homopolymers and copolymers of vinylcaprolactam; homopolymers and copolymers of polyvinyl methyl ether; neutral acrylic homopolymers and copolymers; C1-2 alkyl celluloses and their derivatives; C1-3 alkyl guar; C1-3 hydroxyalkyl guar, wherein the weight ratio of the oily phase to the amphiphilic lipid is 1.2 to 10.

Abstract translation: 目的：提供一种包含油相的水包油纳米乳液，其分散在水相中并且包括数均粒径小于100nm的油球。 因此，所获得的纳米乳液优选在储存时是透明的和稳定的，并且可以形成用于局部，优选化妆品或皮肤病学组合物，药物组合物和眼科学组合物的组合物。 构成：该纳米乳液包含：（i）至少一种选自包括非离子两亲性脂质和阴离子两亲性脂质的两亲性脂质; 和（ii）至少一种选自包括环氧乙烷的均聚物和共聚物的水溶性非离子聚合物; 聚乙烯醇; 乙烯基吡咯烷酮的均聚物和共聚物; 乙烯基己内酰胺的均聚物和共聚物; 聚乙烯基甲醚的均聚物和共聚物; 中性丙烯酸均聚物和共聚物; C1-2烷基纤维素及其衍生物; C1-3烷基瓜尔胶 C1-3羟烷基瓜尔胶，其中油相与两亲性脂质的重量比为1.2〜10。