매생이 추출물 또는 이로부터 분리된 화합물을 유효성분으로 포함하는 당뇨성 합병증 예방 또는 치료용 약제학적 조성물
    1.
    发明公开
    매생이 추출물 또는 이로부터 분리된 화합물을 유효성분으로 포함하는 당뇨성 합병증 예방 또는 치료용 약제학적 조성물 无效
    用于预防或治疗包含卡泊芬粉或其分离的化合物的糖尿病综合症的药物组合物

    公开(公告)号:KR1020130140448A

    公开(公告)日:2013-12-24

    申请号:KR1020120063862

    申请日:2012-06-14

    Abstract: The present invention relates to novel uses of capsosiphon fulvescens extract or compounds isolated therefrom for preventing or treating diabetic complications and, more specifically, to a pharmaceutical composition and a health supplement for preventing or treating diabetic complications which include capsosiphon fulvescens extract, soluble extract of non-polar solvent, or compounds isolated therefrom (capsofulvesin A, capsofulvesin B, chalinasterol) as active ingredients. The capsosiphon fulvescens extracts or compounds isolated therefrom (capsofulvesin A, capsofulvesin B, chalinasterol) have excellent suppression activities on aldose reductase and excellent suppression activities on final glycation products. Therefore, the capsosiphon fulvescens extracts or compounds isolated therefrom can be utilized as medicines such as pharmaceutical compositions and health supplements for preventing or treating diabetic complications so that the value of the capsosiphon fulvescens extracts or compounds isolated therefrom can be extremely high when applying in food and medical industries. Specially, the capsosiphon fulvescens extracts or compounds isolated therefrom in the present invention are substances derived from natural substances and have stability without cytotoxicity so that the compositions of the present invention which includes the same as active ingredients can be safely used for long time.

    Abstract translation: 本发明涉及一种用于预防或治疗糖尿病并发症的胆红素提取物或其分离的化合物的新用途,更具体地,涉及用于预防或治疗糖尿病并发症的药物组合物和健康补充剂,其包括辣椒皂苷提取物,非可溶性提取物, - 极性溶剂,或从其分离的化合物(海藻多柔比星A,棉铃藓素B,沙拉宁醇)作为活性成分。 辣椒油提取物或从其中分离的化合物(海藻多糖A,血浆壳多糖B,沙利度醇)对醛糖还原酶具有优异的抑制活性,对最终糖基化产物具有优异的抑制活性。 因此,辣椒油提取物或其分离的化合物可用作药物,例如用于预防或治疗糖尿病并发症的药物组合物和健康补充剂,从而当应用于食物中时,辣椒素提取物或从其分离的化合物的值可能非常高 医疗行业。 特别地,在本发明中,辣椒油提取物或从其分离的化合物是天然物质衍生的物质,具有稳定性而没有细胞毒性,因此本发明的包含与活性成分相同的组合物可以长时间安全使用。

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