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3.发明公开핵산 분석용 시약 용기, 상기 시약 용기의 제조 방법, 상기 시약 저장 방법, 및 핵산 분석용 미세 유체 시스템 审中-实审用于放大核酸的试剂容器，其制备方法，用于储存试剂的方法和用于分析核酸的微流体系统
公开(公告)号：KR1020140071213A
公开(公告)日：2014-06-11
申请号：KR1020130029921
申请日：2013-03-20
Applicant: 삼성전자주식회사
CPC classification number: C12M1/18 , B01L3/5027 , C12M1/38 , C12Q1/6844
Abstract: The present invention provides a reagent container capable of maintaining the stability of a reagent, a manufacturing method of the reagent container, a method for storing the reagent, and a micro-fluid system which performs cell capture, destruction, and nucleic acid extraction and amplification. According to the method for storing the reagent, the stability of the reagent is maintained and the activity is maintained in a reaction using the reagent.
Abstract translation: 本发明提供能够维持试剂的稳定性的试剂容器，试剂容器的制造方法，储存试剂的方法以及进行细胞捕获，破坏和核酸提取和扩增的微流体系统 。 根据存储试剂的方法，维持试剂的稳定性，并且使用试剂在反应中维持活性。
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公开(公告)号：KR1020140014848A
公开(公告)日：2014-02-06
申请号：KR1020120081967
申请日：2012-07-26
Applicant: 삼성전자주식회사
IPC: C12Q1/68
CPC classification number: C12Q1/6848 , C12Q1/6844 , C12Q2527/125 , C12Q2563/137
Abstract: The present invention relates to a method for enhancing amplification nucleic acids, to a composition and a kit for amplifying nucleic acids which suppress nucleic acid amplification inhibitors, and to a depressant for nucleic acid amplification inhibitors. The present invention can rapidly detect target microorganisms, cells or genes among biological samples with high amplification efficiencies or high sensitivity and be used for accurate molecular diagnosis. [Reference numerals] (AA) Response Unit; (BB) Number of cycles
Abstract translation: 本发明涉及用于增强扩增核酸的方法，组合物和用于扩增抑制核酸扩增抑制剂的核酸的试剂盒和用于核酸扩增抑制剂的抑制剂。 本发明可以以高扩增效率或高灵敏度快速检测生物样品中的目标微生物，细胞或基因，并用于精确的分子诊断。 （附图标记）（AA）响应单元; （BB）循环次数
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公开(公告)号：KR1020130077774A
公开(公告)日：2013-07-09
申请号：KR1020120139270
申请日：2012-12-03
Applicant: 삼성전자주식회사
CPC classification number: G01N1/38 , B01F1/0022 , B01F11/0048 , B01F13/0059 , B01L3/5027 , B01L3/527 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2400/0481 , C12Q1/6806 , G01N35/1002 , Y10T436/25
Abstract: PURPOSE: A solid reagent dissolving device and a method of dissolving a solid reagent using the same are provided to increase reproducibility by completely dissolving the solid reagent. CONSTITUTION: A solid reagent dissolving device includes a flexible membrane (M1), an upper substrate (U1), and a lower substrate (L1). The upper substrate is arranged on the flexible membrane, and the lower substrate is arranged under the flexible membrane. A plurality of microchannels (C1,C2), a dissolution chamber (48), and protrusions (42,44) are arranged on the upper substrate. The dissolution chamber is in connection with the microchannels. The protrusions block the flow of fluid through the microchannels. A plurality of through holes is arranged on the lower substrate and respectively corresponds to the protrusions and the dissolution chamber. Each end of the through holes, the microchannels, and the dissolution chamber are covered with the flexible membrane. A method of dissolving a solid reagent includes the steps of: preparing a solid reagent (46) in the dissolution chamber; supplying a solid reagent dissolving solution to the dissolution chamber; and vibrating a dissolved solution.
Abstract translation: 目的：提供固体试剂溶解装置和使用其的固体试剂的溶解方法，以通过完全溶解固体试剂来提高再现性。 构成：固体试剂溶解装置包括柔性膜（M1），上基板（U1）和下基板（L1）。 上基板布置在柔性膜上，下基板布置在柔性膜下方。 多个微通道（C1，C2），溶解室（48）和突起（42,44）布置在上基板上。 溶解室与微通道相连。 突起阻挡流经微通道的流体。 多个通孔设置在下基板上，分别对应于突起和溶解室。 通孔，微通道和溶解室的每一端均被柔性膜覆盖。 溶解固体试剂的方法包括以下步骤：在溶解室中制备固体试剂（46）; 将固体试剂溶解溶液供应到溶解室; 并振动溶解的溶液。
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Patent Agency Ranking
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公开(公告)号：KR1020130113774A
公开(公告)日：2013-10-16
申请号：KR1020120036243
申请日：2012-04-06
Applicant: 삼성전자주식회사
CPC classification number: G01N27/44791 , B01F11/0048 , B01F13/0052 , B01F13/0059 , B01L3/5027 , B01L2400/0481 , C12N1/066 , G01N1/286 , C12Q1/6834 , G01N2035/00237 , G01N2035/00544
Abstract: PURPOSE: A method for effectively treating a target material in a sample is provided to uniformly regulate surface-to-volume ratio (SVR) of a chamber filled with a solid support, thereby enhancing the interaction of a target material in a sample and the surface of the solid support. CONSTITUTION: A method for treating a target material in a sample comprises the steps of: introducing the sample to a first chamber containing a solid support containing a material which is conjugated with the target material; and conjugating the target material to the solid support. A microfluidic device (20) comprises a first chamber (22) including an inlet and an outlet; a second chamber (24) which is connected to a pressure providing device; and an elastic film which is placed between the first and second chambers and forms a part of a wall of the first and second chambers. During the steps, the elastic film is extended toward the first chamber by providing a positive pressure to the second chamber or the elastic film is extended toward the second chamber by providing a negative pressure to the second chamber.
Abstract translation: 目的：提供一种有效处理样品中的目标材料的方法，以均匀调节填充有固体支持物的室的表面体积比（SVR），从而增强样品中的目标材料与表面的相互作用 的坚实支持。 构成：用于处理样品中的目标材料的方法包括以下步骤：将样品引入含有含有与靶材料共轭的材料的固体支持物的第一室; 并将目标材料与固体支持物共轭。 微流体装置（20）包括包括入口和出口的第一室（22） 连接到压力提供装置的第二室（24）; 以及弹性膜，其被放置在第一和第二室之间并形成第一和第二室的壁的一部分。 在步骤期间，通过向第二室提供正压力使弹性膜向第一室延伸，或者通过向第二室提供负压使弹性膜向第二室延伸。
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公开(公告)号：KR1020120027991A
公开(公告)日：2012-03-22
申请号：KR1020100089922
申请日：2010-09-14
Applicant: 삼성전자주식회사
CPC classification number: C12Q1/6806 , C12Q1/686 , C12Q1/25 , C12Q2527/125
Abstract: PURPOSE: A method for enhancing PCR sensitivity and speed and a composition for the same are provided to quickly detect target microorganisms, cells or genes in a sample. CONSTITUTION: A method for enhancing PCR efficiency and speed comprises: a step of preparing a biological sample and PCR mixture and adding alkali to one or both; and a step of mixing the biological sample and PCR mixture and performing PCR. The biological sample includes cells, body fluid, or nucleic acids. The alkali is sodium hydroxide or potassium hydroxide. A composition for efficient PCR contains the PCR mixture and alkali.
Abstract translation: 目的：提供增强PCR灵敏度和速度的方法及其组合物，以快速检测样品中的目标微生物，细胞或基因。 构成：提高PCR效率和速度的方法包括：制备生物样品和PCR混合物并向一种或两种添加碱的步骤; 以及混合生物样品和PCR混合物并进行PCR的步骤。 生物样品包括细胞，体液或核酸。 碱是氢氧化钠或氢氧化钾。 用于高效PCR的组合物含有PCR混合物和碱。
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公开(公告)号：KR101906969B1
公开(公告)日：2018-10-11
申请号：KR1020170118865
申请日：2017-09-15
Applicant: 삼성전자주식회사
Abstract: 유전자분석장치및 이를이용한유전자분석방법에관해개시되어있다.유전자분석장치는 PCR용샘플이준비되는샘플준비칩과, 상기샘플에대한 PCR이진행되는 PCR 칩과, 상기샘플준비칩과상기 PCR 칩이장착되는패키지층을포함하고, 상기샘플의이동을위한채널을상기패키지층에구비한다. 상기패키지층에상기 PCR 칩에서상기샘플준비칩으로물질이이동되는채널이포함될수 있다. 상기샘플준비칩과상기 PCR 칩은같은방향혹은반대방향을향하도록장착될수 있다.
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公开(公告)号：KR101835006B1
公开(公告)日：2018-03-06
申请号：KR1020100089922
申请日：2010-09-14
Applicant: 삼성전자주식회사
CPC classification number: C12Q1/6806 , C12Q1/686 , C12Q2527/125
Abstract: 중합효소연쇄반응에서반응감도및 속도를증가시키는방법및 고효율및 고감도중합효소연쇄반응용조성물에관한것이다.
Abstract translation: 提高聚合酶链式反应中反应灵敏度和速度的方法，以及用于高效和高灵敏度聚合酶链式反应的组合物。
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