公开(公告)号：KR100450818B1

公开(公告)日：2004-10-01

申请号：KR1020020012730

申请日：2002-03-09

Applicant: 삼성전자주식회사

Inventor： 윤대성 ,  이유섭 ,  임근배 ,  이재창 ,  정문혁

IPC: C12Q1/68 ,  G06F19/20

CPC classification number: C12Q1/686 ,  B01L3/5025 ,  B01L3/5027 ,  B01L7/52 ,  B01L7/54 ,  B01L2300/1827 ,  B01L2300/1861 ,  B01L2300/1883 ,  C12Q2565/629

Abstract: The present invention provides an apparatus for amplifying a polynucleotide, comprising a substrate, a microflow channel system disposed in the substrate and comprising a sample inlet port, a sample flow channel extending from the sample inlet port, and a polynucleotide polymerization reaction chamber in fluid communication with the sample flow channel, a first insulation groove formed around the reaction chamber, and a means for regulating a temperature of the reaction chamber. Accordingly, a multiple chamber device for amplifying a polynucleotide, comprising multiple polymerization reaction chambers formed in a substrate can be manufactured.

Abstract translation: 本发明提供了用于扩增多核苷酸的装置，其包括基底，设置在基底中并包括样本入口的微流通道系统，从样本入口延伸的样本流动通道以及流体连通的多聚核苷酸聚合反应室 与样品流动通道，围绕反应室形成的第一绝缘槽以及用于调节反应室的温度的装置。 因此，可以制造用于放大多核苷酸的多室装置，其包括形成在基板中的多个聚合反应室。

公开(公告)号：KR1020030073255A

公开(公告)日：2003-09-19

申请号：KR1020020012730

申请日：2002-03-09

Applicant: 삼성전자주식회사

Inventor： 윤대성 ,  이유섭 ,  임근배 ,  이재창 ,  정문혁

IPC: C12Q1/68 ,  G06F19/20

CPC classification number: C12Q1/686 ,  B01L3/5025 ,  B01L3/5027 ,  B01L7/52 ,  B01L7/54 ,  B01L2300/1827 ,  B01L2300/1861 ,  B01L2300/1883 ,  C12Q2565/629

Abstract: PURPOSE: Provided is a multi chamber PCR chip which processes a large amount of genetic information with a minimized structure and a reduced reaction time. CONSTITUTION: A polynucleotide amplification PCR chip comprises a sample inject domain minutely formed at a solid substrate; a sample flow channel connected to the sample inject domain; PCR performance chambers fluid-communicated with the sample flow channel; a temperature control unit with one or more thin film heaters connected to the top or the bottom of the chambers and one or more temperature sensors connected to the center of the chambers; and adiabatic grooves surrounding the PCR performance chambers.

Abstract translation: 目的：提供一种多室PCR芯片，其处理大量遗传信息，结构最小化，反应时间缩短。 构成：多核苷酸扩增PCR芯片包含在固体底物上微细形成的样品注入结构域; 连接到样品注入区的样品流动通道; 与样品流通道流体连通的PCR性能室; 具有连接到所述室的顶部或底部的一个或多个薄膜加热器的温度控制单元和连接到所述室的中心的一个或多个温度传感器; 以及围绕PCR性能室的绝热槽。