公开(公告)号：KR1020150128560A

公开(公告)日：2015-11-18

申请号：KR1020150055501

申请日：2015-04-20

Applicant: 삼성전자주식회사

Inventor： 조미영 ,  린포웨이 ,  정광호 ,  황재웅 ,  김건웅 ,  최한나

IPC: C07K16/46 ,  A61K39/395 ,  C07K16/28

Abstract: 항 HER2 scFv 단편, 이를포함하는항 HER2 항체및 항 c-Met/항 HER2 이중특이항체, 및이를포함하는암의예방및/또는치료용약학적조성물이제공된다.

Abstract translation: 提供抗HER2 scFV片段，抗HER2抗体和包含其的抗c-Met /抗HER2双特异性抗体，以及包含其的药物组合物，用于预防和/或治疗癌症。

公开(公告)号：KR1020140120831A

公开(公告)日：2014-10-14

申请号：KR1020140037574

申请日：2014-03-31

Applicant: 삼성전자주식회사

Inventor： 정수연 ,  조미영 ,  송윤정 ,  최한나

IPC: C07K16/42 ,  G01N33/53 ,  A61K39/395 ,  A61P35/00

CPC classification number: C07K16/4258 ,  C07K2317/56 ,  C07K2317/565

Abstract: According to an embodiment of the present invention, provided is an anti-idiotype antibody against anti-c-Met antibody and, more specifically, provided is an anti-idiotype antibody against an anti-c-Met antibody specifically binding to (and/or recognizing) the idiotope region of the anti-c-Met antibody. The anti-idiotype antibody against the anti-c-Met antibody is an antibody to recognize the idiotope of the c-Met antibody as an epitope, specifically targeting the idiotope of the anti-c-Met antibody or specifically binding to the idiotope of the c-Met antibody.

Abstract translation: 根据本发明的一个实施方案，提供了针对抗c-Met抗体的抗独特型抗体，更具体地说，提供了针对特异性结合（和/或）抗-c-Met抗体的抗c-Met抗体的抗独特型抗体 识别）抗c-Met抗体的特异性区域。 针对抗c-Met抗体的抗独特型抗体是将c-Met抗体的特异性识别为表位的抗体，特异性靶向抗c-Met抗体的特异性或特异性结合到抗-c-Met抗体的特异性 c-Met抗体。