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公开(公告)号：KR101706047B1
公开(公告)日：2017-02-16
申请号：KR1020150122653
申请日：2015-08-31
Applicant: 서강대학교산학협력단
Abstract: 본발명은아토피치료용유전체약물을응축시키고외부를히알루론산으로코팅하여유전체수준에서아토피질환을치료할수 있는유전체나노입자및 이의제조방법에관한것이다. 본발명은아토피질환유전자를표적하는핵산하이드로젤입자외곽에양이온성고분자층과히알루론산층을더 포함하므로피부내 RNA를분해시키는효소로부터핵산입자를보호할수 있다. 또한, 본발명은마이크로사이즈또는이에준하는나노사이즈의크기를갖는 TNF-α siRNA 하이드로젤을응축시켜나노사이즈로입자크기를줄이고, 또한, 최외곽층을 (-) 전하를띄는히알루론산으로코팅함에따라피부장벽통과가용이한유전체나노입자를제공할수 있다.
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Patent Agency Ranking
公开(公告)号：KR102075823B1
公开(公告)日：2020-02-10
申请号：KR1020170132259
申请日：2017-10-12
Applicant: 서강대학교산학협력단
IPC: A61K9/51 , A61K31/704 , A61K49/04
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公开(公告)号：KR102076518B1
公开(公告)日：2020-02-13
申请号：KR1020180015930
申请日：2018-02-08
Applicant: 서강대학교산학협력단 , 서울대학교산학협력단 , (주)아이엠지티
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公开(公告)号：KR1020130126266A
公开(公告)日：2013-11-20
申请号：KR1020120050239
申请日：2012-05-11
Applicant: 서강대학교산학협력단 , 서울대학교병원
Abstract: The present invention relates to intraocular drug delivery implant which enables continuous intraocular drug release in a desired direction and a method for manufacturing the same. The implant according to the present invention is cheap and efficient because the implant can control the release of a drug in unintended directions using a non-permeating unit. Also, the implant by the present invention is formed in a desired shape by coating a drug with a permeable layer and a non-permeable layer.
Abstract translation: 本发明涉及能够在期望的方向上连续的眼内药物释放的眼内药物递送植入物及其制造方法。 根据本发明的植入物便宜且高效，因为植入物可以使用非渗透单元来控制药物在非预期方向的释放。 此外，本发明的植入物通过用可渗透层和不可渗透层涂覆药物而形成为期望的形状。
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