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公开(公告)号:KR1020100025452A
公开(公告)日:2010-03-09
申请号:KR1020080114716
申请日:2008-11-18
Applicant: 서울대학교산학협력단
CPC classification number: G01N33/54373 , C12Q1/6837 , C40B40/08 , C40B40/10 , C12Q2565/628 , G01N21/554
Abstract: PURPOSE: A molecular detection substrate using a surface Plasmon resonance(SPR) is provided to increase the number of nanodots and improve signal versus noise ratio. CONSTITUTION: A target molecule detection substrate using a surface Plasmon resonance(SPR) comprises: a detection zone placed on the surface of the substrate; and plural collection of nanodots placed inside the detection zone. The nanodot is functionalized to one or more probes having affinity to a target molecule. The range of detection zone is 1um^2 to 10,000 um^2. The plural nanodots form grating pattern, spiral pattern, planar concentric circle or radiation pattern. The diameter of the nanodot is 1 nm-100 nm. The nanodot contains gold(Au), silver(Ag), copper(Cu) or aluminum(Al).
Abstract translation: 目的:提供使用表面等离子体共振(SPR)的分子检测基板,增加纳米点的数量,提高信噪比。 构成:使用表面等离子体共振(SPR)的靶分子检测基板包括:放置在基板表面上的检测区域; 以及放置在检测区内的多个纳米点集合。 该纳米点被功能化为对目标分子具有亲和力的一种或多种探针。 检测范围为1um ^ 2〜10,000um ^ 2。 多个纳米点形成光栅图案,螺旋图案,平面同心圆或辐射图。 纳米点的直径为1nm-100nm。 该纳米点含有金(Au),银(Ag),铜(Cu)或铝(Al)。