公开(公告)号：KR1020120137642A

公开(公告)日：2012-12-24

申请号：KR1020110056137

申请日：2011-06-10

Applicant: 서울대학교산학협력단

Inventor： 김영식 ,  박유미 ,  임아랑

IPC: A61K9/16 ,  A61K47/02 ,  A61K31/737

CPC classification number: A61K9/5161 ,  A61K9/06 ,  A61K9/5192 ,  A61K33/38 ,  Y10S514/97

Abstract: PURPOSE: A silver nanoparticle using chondroitin sulfate or acharan sulfate is provided to suppress bacteria without toxicity and to enable quick wound healing. CONSTITUTION: A biocompatible silver nanoparticle improves safety, stability, and wound healing effect using chondroitin sulfate or acharan sulfate. The size of the silver nanoparticle is 5-50 nm. A method for preparing the silver nanoparticles comprises: a step of dissolving chondroitin sulfate or acharan sulfate in 0.01-2.0 mM of distilled water to prepare a reducing agent solution; a step of dissolving 0.01-10.0 mM nitric acid in distilled water to prepare a nitric acid solution; a step of mixing the reducing agent solution and nitric acid solution to prepare a mixture solution; and a step of reacting the mixture solution in an autoclave or microwave.

Abstract translation: 目的：提供使用硫酸软骨素或硫酸沙卡糖的银纳米颗粒，以抑制细菌无毒性，并能快速伤口愈合。 构成：生物相容性银纳米颗粒使用硫酸软骨素或硫酸阿卡拉酸提高安全性，稳定性和伤口愈合效果。 银纳米颗粒的尺寸为5-50nm。 制备银纳米颗粒的方法包括：将硫酸软骨素或硫酸阿卡沙溶解在0.01-2.0mM蒸馏水中以制备还原剂溶液的步骤; 将0.01-10.0mM硝酸溶解在蒸馏水中以制备硝酸溶液的步骤; 将还原剂溶液和硝酸溶液混合以制备混合溶液的步骤; 以及在高压釜或微波炉中使混合溶液反应的步骤。