Abstract:
본 발명은 토목향(Inula helenium) 분획물 또는 이로부터 분리된 화합물을 유효성분으로 함유하는 유방암 예방 및 치료용 약학적 조성물에 관한 것으로서, 구체적으로 유방암 세포 및 유방암 세포가 이식된 마우스에 대하여 STAT3의 타이로신 인산화 활성을 선택적으로 저해 효과를 나타내고, STAT3 타겟 유전자의 발현을 하향 조절 효과를 나타내며, 암 전이 억제 효과를 나타내고, 종양 무게 및 종양 부피 감소 효과를 나타내므로, 상기 토목향 분획물 또는 이로부터 분리된 화합물은 유방암 예방 및 치료용 약학적 조성물, 유방암 전이 억제용 조성물, 유방암 예방 및 개선용 건강기능식품, 유방암 전이 억제용 건강기능식품, 또는 항암 보조제의 유효성분에 효과적으로 사용될 수 있다.
Abstract:
The present invention relates to a device for detecting an attack on a vehicle network and a method thereof and is to provide to a device for detecting an attack on a vehicle network and a method thereof which accumulatively counts packets by each device (ID) connected to a vehicle network bus, calculates the accumulated value by accumulating an inspected value (S) whenever accumulatively counting packets and determines that an attack is occurred if the average accumulated value calculated by dividing the accumulated value by the accumulated counting does not exceed a first threshold value. For the purpose, in a vehicle network environment in which devices, having a priority for packet transmission, connected to a vehicle network bus include: a packet collection unit for collecting packets transmitted through the vehicle network bus; a packet counting unit for accumulatively counting the number of packets collected by the packet collection unit; an inspected value calculation unit for calculating an inspected value based on a time difference between packets having the same ID; an accumulated value calculation unit for calculating an accumulated value by adding the inspected value which is calculated by the inspected value calculation unit to the previous inspected value; an average accumulated value calculation unit for calculating the average accumulated value by dividing the accumulated value calculated by the accumulated value calculation unit by accumulated counting value by the packet counting unit; and an attack determination unit for determining the existence of attack based on the average accumulated value calculated by the average accumulated value calculation unit. [Reference numerals] (10) Packet collection unit; (20) Packet counting unit; (30) Inspected value calculation unit; (40) Accumulated value calculation unit; (50) Average accumulated value calculation unit; (60) Attack determination unit; (70) Control unit