公开(公告)号：KR1020100062336A

公开(公告)日：2010-06-10

申请号：KR1020080120932

申请日：2008-12-02

Applicant: 서울대학교산학협력단

Inventor： 홍석철 ,  이남경 ,  이경진 ,  박진성 ,  현주용

IPC: C12Q1/68 ,  G01N33/48

CPC classification number: G06F19/16 ,  C12Q1/68

Abstract: PURPOSE: A method for measuring elasticity of DNA targeting drug-bound DNA and a method for measuring binding degree of DNA and DNA targeting drug are provided to find physical property of DNA. CONSTITUTION: A method for measuring elasticity of DNA targeting drug-bound DNA is performed by measuring tension and length to a binding DNA. A method for measuring relation of tension and length is defined by WLC having changing continuous length by formula 3 in force-length curve of WLC model of formula 1 in case of lack of interelation between kinks generated by binding. The binding with DNA targeting drug is performed in a proper tension and salt concentration.

Abstract translation: 目的：提供一种测定靶向药物结合DNA的DNA弹性的方法以及测定DNA和DNA靶向药物结合程度的方法，以找出DNA的物理性质。 构成：通过测量结合DNA的张力和长度来测量靶向药物结合的DNA的DNA的弹性的方法。 用于测量张力和长度关系的方法由WLC定义，WLC在结合产生的扭结之间缺乏相互作用的情况下，通过公式3的WLC模型的力 - 长度曲线中具有连续长度改变的连续长度。 与DNA靶向药物的结合以适当的张力和盐浓度进行。

公开(公告)号：KR102238149B1

公开(公告)日：2021-04-08

申请号：KR1020200067173

申请日：2020-06-03

Applicant: 한화에어로스페이스 주식회사 ,  서울대학교산학협력단

Inventor： 박진성 ,  김기범 ,  김현미 ,  김민식

IPC: G01N21/88 ,  G01N21/95 ,  G01N21/84 ,  G01N17/00 ,  G06T7/00

Abstract: 동박(銅薄)의제1층에그래핀의제2층이합성된결과의그래핀-합성동박에대하여, 제2층의그래핀의합성품질을검사하는방법으로서, 단계 (a) 내지 (f)를포함한다. 단계 (e)에서, 부분영역의영상들각각에대하여, 전체면적에대한그래핀결함면적의비율을구한다. 단계 (f)에서, 부분영역의영상들각각에대하여, 그래핀결함면적의비율이기준값보다낮은지의여부에따라양호또는불량을판정한다. 상기기준값은, 그래핀-합성동박의표본들에대한실험에의하여설정되되, 그래핀의전기적물성값이변하지않게하는그래핀결함면적의비율들중에서가장높은비율로서설정된다.