Abstract:
본원은 세포를 p62 단백질, 상기 p62 단백질의 ZZ 영역 또는 상기 ZZ 영역의 128 내지 163 잔기와 상호작용하는 N-end rule 라이겐드와 접촉하는 단계를 포함하는 자가포식 조절 방법 및 그 용도를 개시한다. 본원에 따른 p62를 이용한 N-end rule 경로를 통한 단백질 제거는 변성된 단백질의 비정상적인 축적으로 인한 다양한 질환의 치료 또는 예방을 위한 치료제 개발에 유용하게 사용될 수 있다.
Abstract:
PURPOSE: A bipolar plate of a fuel cell is provided to ensure strong corrosive resistance and excellent electroconductivity and to improve the lifetime and performance of a fuel cell. CONSTITUTION: A bipolar plate(35,40) of a fuel cell includes 316L stainless steel which has the nitrified surface and corrosion potential of 0.1V or more and 0.15V or less, or 316L stainless steel to which nitrogen of 15% or more and 25% or less based on the total composition ratio is impregnated to the surface thereof. A method for preparing the bipolar plate of the fuel cell comprises a step for nitrifying the surface of a substrate including stainless steel at the temperature of 270°C or more and 330°C or less.
Abstract:
PURPOSE: A bipolar plate for a fuel cell is provided to improve corrosion resistance and performance of a fuel battery by comprising a titanium oxide film. CONSTITUTION: A bipolar plate(35,40) for a fuel cell comprises stainless steel and a titanium oxide layer containing titanium 43-44%, nitrogen 44-45%, and oxygen 12-14% applied on the surface of the stainless steel. A method for manufacturing the bipolar plate for a fuel cell comprises the steps of: loading a chamber containing mixed gas including oxygen, nitrogen and argon on a substrate; and coating the surface of the substrate with a titanium oxynitride film while injecting oxygen 0.2 sccm.