Abstract:
본 발명은 세신, 길경 및 계지로 이루어진 군에서 선택되는 2종 이상의 혼합 추출물을 유효성분으로 포함하는 알레르기성 질환의 예방 또는 치료용 약학 조성물, 상기 약학 조성물을 이용한 알레르기성 질환의 예방 또는 치료방법, 알레르기성 질환 개선용 건강기능식품 및 사료 조성물에 관한 것이다. 본 발명에서 제공하는 세신, 길경 및 계지로 이루어진 군에서 선택되는 2종 이상의 혼합 추출물을 유효성분으로 포함하는 조성물은 Th2 세포 분화를 특이적으로 억제하여 알레르기성 질환에 대한 예방 또는 치료용 조성물로 유용하게 사용될 수 있다.
Abstract:
본원은 세포노화 마커로서 사용가능한 라이소포스파티딜콜린 및 라이소포스파티딜에탄올아민의 검출용 물질을 포함하는 줄기세포 노화 판별 조성물 및 그 용도를 개시한다. 본원에 따른 조성물은 인비트로 배양을 통한 증폭이 필수적인 줄기세포의 배양에 있어, 세포의 품질관리는 물론 임상 등에 적용전에 노화여부를 판별할 수 있어 임상적용의 성공률을 높일 수 있다.
Abstract:
PURPOSE: An underground tunnel using a continuous incremental launching method and a construction method thereof are provided to reduce construction time and costs by easily producing a tube tunnel body. CONSTITUTION: An underground tunnel using a continuous incremental launching method comprises an excavated hole(100), a tube tunnel body(200), supporters(320), and a bottom plate. The excavated hole has a tunnel entrance(101) and a tunnel exit. The tube tunnel body is inserted into the excavated hole. The supporters are formed in the bottom of the excavated hole and support the tube tunnel body. The bottom plate is installed in the inner bottom of the tube tunnel body.
Abstract:
PURPOSE: A method and kit for diagnosing sensitivity of an anti-cancer drug is provided to predict treatment process of colon cancer by administering ginsenoside Rg3. CONSTITUTION: A method for diagnosing anti-cancer drug sensitivity is performed using a protein marker of which expression increased or decreased by ginsenoside Rg3 in colon cancer cells. The protein marker is stathmin 1(gi|5031851), proliferating cell nuclear antigen(gi|49456555), serine/threonine kinase receptor-relating protein(gi|148727341), glutathione S-transferase P1(gi|119595056), or clathrin(gi|4502899). A method for isolating protein marker comprises: a first step of collecting protein from colon cancer cells; a second step of isolating protein through IEF(isoelectric focus) in a range of pH 4-7; a third step of isolating protein in Large size(17x17cm) SDS gel by electrophoresis; a fourth step of dyeing the protein with silver and confirming protein spot using an analyzer; a fifth step of confirming peptide information of the spot; a final step of confirming the protein name and determining by anticancer activity relating index. The anti-cancer drug is ginsenoside Rg3, 5-FU, UFT, capecitabine, irinotecan or oxaliplatin.
Abstract:
PURPOSE: A composition for preventing and treating thrombosis containing ginsenoside isolated from processed ginseng extract is provided to ensure blood platelet aggregation without side effects and cytotoxicity. CONSTITUTION: A pharmaceutical composition for preventing and treating thrombosis contains processed ginseng extract or ginsenoside compound isolated from the extract as an active ingredient. The processed ginseng extract is obtained by heating ginseng at 70-150°C for 2 to 6 hours. The ginsenoside compound is ginsenoside Rk1, ginsenoside Rg5, 20(S)-ginsenoside Rg3 or 20(R)-ginsenoside Rg3. Thrombosis is artery scleroma, embolus, ischemic heart disease, stroke, angina, the cerebral infarction, immunocompromised host, blood tumor, atherothrombosis, cirrhosis of the kidney or myocardial infarction. A functional health food is powder, granule tablet, capsule, syrup, or beverage.
Abstract:
본발명은크로마토그래프지문의유사성비교를통한원료의품질평가방법에관한것으로, 본발명을이용하면원료내 대사체성분정보에대한이해(시너지효과와직결된성분들의조성비율, 성분들의부분적/전반적농도이상등)가직관적으로가능하다. 따라서, 복합유사성지표와통계분석을통해원료를품질평가함으로써더 엄격하고과학적으로생약원료의품질을판단할수 있다.