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    4―디메틸아미노―2―메톡시―6―（（메틸―［2―（4―니트로페닐）에틸］아미노）메틸）페놀을 포함하는 항염증용 조성물
    1.
    发明公开
    4―디메틸아미노―2―메톡시―6―（（메틸―［2―（4―니트로페닐）에틸］아미노）메틸）페놀을 포함하는 항염증용 조성물 有权
    包含4-二甲基氨基-2-甲氧基-6-（（甲基 - [2-（4-硝基苯基）乙基]氨基）甲基）苯酚用于抗炎的组合物

    公开(公告)号：KR1020140018501A

    公开(公告)日：2014-02-13

    申请号：KR1020120084641

    申请日：2012-08-02

    Applicant: 성균관대학교산학협력단

    Inventor： 조재열 ,  홍성렬 ,  양얀얀 ,  김시형 ,  김지혜 ,  김은지

    IPC: A61K31/05 ,  A61K31/04 ,  A61P29/00

    Abstract: The present invention relates to a pharmaceutical composition, a food composition, and a cosmetic composition containing 4-dimethylamino-2-methoxy-6-((methyl-[2-(4-nitrophenyl)ethyl]methyl) phenol as an active ingredient for anti-inflammation. The compositions in the present invention have an excellent anti-inflammation effect by basically decreasing the formation of TNF-α, PGE2, and NO from the transcription step. Also the compositions show no cytotoxicity even in case of high-dose treatment, thereby being applicable for medicine, foods, and cosmetics safely. Thus, the compositions are expected to be importantly applicable as an anti-inflammatory drug.

    Abstract translation: 本发明涉及含有4-二甲基氨基-2-甲氧基-6 - （（甲基 - [2-（4-硝基苯基）乙基]甲基）苯酚作为活性成分的药物组合物，食品组合物和化妆品组合物 本发明的组合物通过从转录步骤基本上降低TNF-α，PGE2和NO的形成而具有优异的抗炎作用，即使在高剂量治疗的情况下，组合物也不显示细胞毒性 因此安全地适用于医药，食品和化妆品，因此预期该组合物作为抗炎药可以重要地应用。

    2，3―비스［（2―하이드록시에틸）티오］―1，4―나프토퀴논을 포함하는 항염증용 조성물
    2.
    发明公开
    2，3―비스［（2―하이드록시에틸）티오］―1，4―나프토퀴논을 포함하는 항염증용 조성물 有权
    包含2,3-BIS [（2-羟基乙基）硫代] -1,4-萘醌用于抗炎的组合物

    公开(公告)号：KR1020140017199A

    公开(公告)日：2014-02-11

    申请号：KR1020120083743

    申请日：2012-07-31

    Applicant: 성균관대학교산학협력단

    Inventor： 조재열 ,  홍성렬 ,  양얀얀 ,  김한경 ,  김지혜 ,  김은지

    IPC: A61K31/122 ,  A61P29/00

    CPC classification number: A61K31/122 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/324 ,  A61K8/355 ,  A61Q19/00

    Abstract: The present invention relates to a pharmaceutical composition, a food composition, and a cosmetic composition for anti-inflammation, containing 2,3-Bis[(2-hydroxyethyl)thio]-1,4-naphthoquinone as an active ingredient. The composition of the present invention fundamentally reduces the generation of TNF-α, PGE_2, and NO, which are inflammation-related factors, from the transcriptional stage, thereby exhibiting excellent anti-inflammatory effect. Further, the composition of the present invention can be safely applied to medicines, food, and cosmetics since it does not exhibit cytotoxicity in spite of treatment at high concentration. Accordingly, the composition of the present invention is expected to be significantly applied as an anti-inflammatory agent.

    Abstract translation: 本发明涉及含有2,3-双[（2-羟乙基）硫代] -1,4-萘醌作为活性成分的药物组合物，食品组合物和抗炎化妆品组合物。 本发明的组合物从转录阶段基本上降低了作为炎症相关因子的TNF-α，PGE_2和NO的产生，从而表现出优异的抗炎作用。 此外，本发明的组合物可以安全地应用于药物，食品和化妆品，因为尽管在高浓度下处理不具有细胞毒性。 因此，预期本发明的组合物可以显着地用作抗炎剂。

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