公开(公告)号：KR1020100033573A

公开(公告)日：2010-03-31

申请号：KR1020080092515

申请日：2008-09-22

Applicant: 성균관대학교산학협력단

Inventor： 지옥표 ,  박종혁 ,  이종욱 ,  김일환 ,  정의수 ,  윤재웅 ,  마진열 ,  이재훈

IPC: A61K36/28 ,  A61P39/06 ,  A61P29/00

Abstract: PURPOSE: A composition containing Chrysanthemum x morifolium extract is provided to suppress degranulation of mast cells and anaphylactic shock and relieve atopic dermatitis. CONSTITUTION: A method for producing Chrysanthemum x morifolium extract comprises: a step of mixing Chrysanthemum x morifolium and depositing; a step of extracting deposition product by an ultrasonic extractor; and a step of filtering the extract. The solvent contains 8.0 weight% of ethanol, 24.0 weight% of 1,3-butyleneglycol, and 48.0 weight% of purified water. The ultrasonic wave extraction is performed by treating at 40°C, 40kHz, and 300 Watt for one hour and treating at 50°C, 40kHz, and 500 Watt for 1 hour. A composition for preventing and treating inflammatory diseases contains 0.001-5 weight% of Chrysanthemum x morifolium extract.

Abstract translation: 目的：提供含有菊花提取物的组合物，以抑制肥大细胞的脱粒和过敏性休克，缓解特应性皮炎。 构成：生产菊花提取物的方法包括：将菊花混合并沉淀的步骤; 通过超声提取器提取沉积物的步骤; 以及过滤提取物的步骤。 溶剂含有8.0重量％的乙醇，24.0重量％的1,3-丁二醇和48.0重量％的净化水。 超声波提取通过在40℃，40kHz和300瓦处理1小时进行处理，并在50℃，40kHz和500瓦处理1小时。 用于预防和治疗炎性疾病的组合物含有0.001-5重量％的菊花提取物。