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1.发明申请셀레노펜-접합 방향족 화합물, 및 이의 제조 방법 审中-公开SELENOPHENE-FUSED AROMATIC COMPOUND AND MANUFACTURING METHOD THEREOF
公开(公告)号：WO2013048177A2
公开(公告)日：2013-04-04
申请号：PCT/KR2012/007905
申请日：2012-09-28
Applicant: 세종대학교산학협력단 , 사회복지법인 삼성생명공익재단
CPC classification number: C07D517/04 , C07D345/00 , C07D421/06
Abstract: 셀레노펜-접합 방향족(selenophene-fused aromatic) 화합물, 및 상기 셀레노펜-접합 방향족 화합물의 제조 방법에 관한 것이다.
Abstract translation: 提供硒酚稠合芳香族化合物，以及硒代苯并稠合芳族化合物的制造方法。
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公开(公告)号：KR101243696B1
公开(公告)日：2013-03-15
申请号：KR1020120054269
申请日：2012-05-22
Applicant: 서울대학교산학협력단 , 세종대학교산학협력단 , 한국생명공학연구원
IPC: A61K31/41 , A61K31/4155 , A61K31/381 , A61K31/18
CPC classification number: A61K31/4155 , A23K20/137 , A23L29/035 , A23L29/045 , A23L29/055
Abstract: PURPOSE: A quorum sensing inhibitor and an antibacterial composition using the same are provided to suppress quorum sensing between bacteria, and to prevent or treat infection or diseases. CONSTITUTION: An antibacterial composition using a quorum sensing inhibitor against a pathogenic microorganism contains 1-(5-bromothiophene-2-sulfonyl)-1H pyrazole of chemical formula 1 as an active ingredient. The antibacterial composition is a pharmaceutical composition, a feed composition, a food composition, and a food additive composition.
Abstract translation: 目的：提供一种群体感应抑制剂和使用其的抗菌组合物，以抑制细菌之间的群体感应，并预防或治疗感染或疾病。 构成：使用针对致病微生物的群体感应抑制剂的抗菌组合物含有化学式1的1-（5-溴噻吩-2-磺酰基）-1H-吡唑作为活性成分。 抗菌组合物是药物组合物，饲料组合物，食品组合物和食品添加剂组合物。
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公开(公告)号：KR101535883B1
公开(公告)日：2015-07-13
申请号：KR1020120145699
申请日：2012-12-13
Applicant: 세종대학교산학협력단 , 서울대학교산학협력단
IPC: C07D493/22 , A61K31/335 , A61P35/00
Abstract: 펙테노톡신-2 유도체, 및상기펙테노톡신-2 유도체를포함하는항암조성물에관한것이다.
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公开(公告)号：KR1020130069463A
公开(公告)日：2013-06-26
申请号：KR1020120145699
申请日：2012-12-13
Applicant: 세종대학교산학협력단 , 서울대학교산학협력단
IPC: C07D493/22 , A61K31/335 , A61P35/00
Abstract: PURPOSE: A pectenotoxin-2 derivative with various useful physical properties is provided to be used as an anticancer agent or a precursor thereof. CONSTITUTION: A pectenotoxin-2 derivative is denoted by chemical formula 1. An anticancer composition contains the derivative and removes cancer cells in human body. The cancer cells include cancer cells of lung, colon, central nervous system, skin, ovary, kidney, breast, or stomach.
Abstract translation: 目的：提供具有各种有用物理性质的果胶毒素-2衍生物作为抗癌剂或其前体。 构成：化学式1表示果胶毒素-2衍生物。抗癌组合物含有衍生物并去除人体中的癌细胞。 癌细胞包括肺，结肠，中枢神经系统，皮肤，卵巢，肾，乳腺或胃的癌细胞。
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公开(公告)号：KR101460207B1
公开(公告)日：2014-11-11
申请号：KR1020120139440
申请日：2012-12-04
Applicant: 세종대학교산학협력단 , 사회복지법인 삼성생명공익재단
IPC: C07D421/06 , C07D421/14 , A61K31/555 , A61P35/00
Abstract: 셀레노펜-접합 방향족(selenophene-fused aromatic) 화합물을 포함하는 항암제에 관한 것이다.
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Patent Agency Ranking
公开(公告)号：KR1020140009091A
公开(公告)日：2014-01-22
申请号：KR1020130153273
申请日：2013-12-10
Applicant: 세종대학교산학협력단 , 사회복지법인 삼성생명공익재단
IPC: C07C391/02 , C07D317/46 , C07D211/80 , C07D491/06
Abstract: The present invention relates to a novel method for producing a selenyl-substituted aromatic aldehyde compound, specifically a novel method for producing a selenyl-substituted aromatic aldehyde compound including a step of forming a selenolate nucleophile and nucleophilic-substituting an aromatic aldehyde starting material.
Abstract translation: 本发明涉及一种制备烯酰基取代的芳族醛化合物的新方法，特别是一种制备烯酰基取代的芳族醛化合物的新方法，包括形成硒酸酯亲核试剂和亲核取代芳族醛起始原料的步骤。
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公开(公告)号：KR101518980B1
公开(公告)日：2015-05-11
申请号：KR1020140133014
申请日：2014-10-02
Applicant: 세종대학교산학협력단 , 사회복지법인 삼성생명공익재단
IPC: C07D421/06 , C07D421/14 , A61K31/555 , A61P35/00
Abstract: 셀레노펜-접합 방향족(selenophene-fused aromatic) 화합물을 포함하는 항암제에 관한 것이다.
Abstract translation: 包含硒酚稠合芳族化合物的抗癌剂。
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公开(公告)号：KR101349752B1
公开(公告)日：2014-01-13
申请号：KR1020120043678
申请日：2012-04-26
Applicant: 울산대학교 산학협력단 , 세종대학교산학협력단
Abstract: 본 발명은 특정 화합물 또는 그의 염을 유효성분으로 함유하는 항균용 조성물에 관한 것으로, 상기 화합물 또는 그의 염은 항균용 약제 또는 건강식품 외에도 인공삽입물, 예를들어 중심정맥관, 인공관절, 인공판막 등에 코팅함으로써 인공삽입물의 바이오필름 형성을 억제함과 동시에 세균을 직접적으로 억제하는 항균활성을 나타낼 수 있어 인공삽입물 감염 방지를 위한 코팅 조성물로서 매우 유용하게 사용될 수 있다.
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公开(公告)号：KR1020130034638A
公开(公告)日：2013-04-05
申请号：KR1020120109215
申请日：2012-09-28
Applicant: 세종대학교산학협력단 , 사회복지법인 삼성생명공익재단
IPC: C07C391/00 , A61K31/095 , A61P35/00
Abstract: PURPOSE: A manufacturing method of a selenophene-fused aromatic compound is provided to obtain various selenophene-fused aromatic compounds at a high yield by varying the kinds of aromatic stating materials. CONSTITUTION: A manufacturing method of a selenophene-fused aromatic compound represented by chemical formula 2 comprises: a step of preparing a diselenide compound represented by chemical formula R^1-CH2-Se-Se-CH2-R^1, a solvent, and a reducing agent; and a step of conducting a reaction by adding an aromatic starting material represented by chemical formula 1 and a base into the reaction mixture. The solvent is selected among dimethylsulfoxide, tetrahydrofuran, CH2Cl2, CH3CN, CH3NO2, CHCl3, ClCH2, CH2Cl, alcohol, an aromatic solvent, and a combination thereof.
Abstract translation: 目的：提供硒代酚稠合芳香族化合物的制造方法，通过改变芳族化合物的种类，以高收率得到各种硒酚稠合芳香族化合物。 构成：由化学式2表示的硒吩酚稠合芳族化合物的制造方法包括：制备由化学式R 1〜2-Se-Se-CH 2 -R 1表示的二硒化合物的溶剂，溶剂和 还原剂; 以及通过将由化学式1表示的芳族起始原料和碱添加到反应混合物中进行反应的步骤。 溶剂选自二甲基亚砜，四氢呋喃，CH 2 Cl 2，CH 3 CN，CH 3 NO 2，CHCl 3，ClCH 2，CH 2 Cl，醇，芳族溶剂及其组合。
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