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公开(公告)号：KR101703436B1
公开(公告)日：2017-02-06
申请号：KR1020150108988
申请日：2015-07-31
Applicant: 숭실대학교산학협력단
Abstract: 본발명은 EDTA를이용한 Cr(III)의검출방법에관한것으로, 보다상세하게는물과같은시료중에함유된 Cr(III) 이온을 EDTA와먼저반응시킨후, 상기 Cr(III)-EDTA 복합체가은나노입자와결합하고은나노입자를응집시켜표면증강라만산란(SERS)법을통해시료중에함유된 Cr(III) 이온을 500 nM의검출한계로검출할수 있으며, 특히방해이온의영향없이선택적으로손쉽고간편하게증류수, 수돗물, 강물및 바닷물에함유된 Cr(III)을검출할수 있다.
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公开(公告)号：KR101374221B1
公开(公告)日：2014-03-14
申请号：KR1020120037960
申请日：2012-04-12
Applicant: 숭실대학교산학협력단
Abstract: 본 발명은 TiO
2
나노 입자-안트라사이클린계 화합물의 복합체, 이를 포함하는 약물 전달 시스템에 관한 것이다. 본 발명에 따른 TiO
2
나노 입자-안트라사이클린계화합물의 복합체는 세포 또는 생체에서 안정성이 있어, 안트라사이클린계 화합물을 안전하게 세포 또는 생체에 약물을 전달하고, 방출시킬 수 있으며, 상기 복합체를 이용하여 약물의 전달 및 방출과정을 실시간으로 관찰할 수 있다.-
公开(公告)号：KR1020130118576A
公开(公告)日：2013-10-30
申请号：KR1020120041543
申请日：2012-04-20
Applicant: 숭실대학교산학협력단
IPC: A61K31/52 , A61K9/16 , A61K47/48 , A61K31/519
Abstract: PURPOSE: A gold nanoparticle-purine complex is provided to show stability in cells or in vivo, to safely deliver a drug, and to release purine-based compounds at a desired time. CONSTITUTION: A gold nanoparticle-purine complex is provided. A purine compound is 6-mercaptopurine or 6-thioguanine. A drug delivery system has the gold nanoparticle-purine complex and glutathione. In the drug delivery system, the purine-based compounds are released from the gold nanoparticle-purine complex by treating the gold nanoparticle-purine complex with glutathione.
Abstract translation: 目的：提供金纳米颗粒 - 嘌呤复合物，以显示细胞或体内的稳定性，以安全递送药物，并在期望的时间释放嘌呤类化合物。 构成：提供金纳米颗粒 - 嘌呤复合物。 嘌呤化合物是6-巯基嘌呤或6-硫鸟嘌呤。 药物递送系统具有金纳米颗粒 - 嘌呤复合物和谷胱甘肽。 在药物递送系统中，通过用谷胱甘肽处理金纳米颗粒 - 嘌呤复合物，嘌呤类化合物从金纳米颗粒 - 嘌呤复合物释放。
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公开(公告)号：KR1020110047921A
公开(公告)日：2011-05-09
申请号：KR1020090104726
申请日：2009-10-31
Applicant: 숭실대학교산학협력단
Abstract: PURPOSE: A fluorescence and SERS detection method of Hg(II) concentration on gold nanocolloid surface is provided to detect Hg ion of low concentration. CONSTITUTION: A method for measuring Hg(II) concentration of an aqueous solution comprises: a step of binding an organic fluorescence dye and obtaining SERS spectrum of the organic fluorescence dye; a step of adding Hg(II) in the aqueous solution to the gold nanoparticles and obtaining SERS spectrum of the organic fluorescence dye; and a step of comparing two SERS spectrum intensity. The organic fluorescence dye is rhodamine 6G or rhodamine 123.
Abstract translation: 目的：提供金纳米胶体表面Hg（II）浓度的荧光和SERS检测方法，以检测低浓度汞离子。 构成：用于测量水溶液的Hg（II）浓度的方法包括：结合有机荧光染料并获得有机荧光染料的SERS光谱的步骤; 将水溶液中的Hg（II）加入金纳米颗粒并获得有机荧光染料的SERS光谱的步骤; 并比较两个SERS光谱强度的步骤。 有机荧光染料是罗丹明6G或罗丹明123。
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Patent Agency Ranking
公开(公告)号：KR101689542B1
公开(公告)日：2016-12-26
申请号：KR1020150007125
申请日：2015-01-15
Applicant: 숭실대학교산학협력단
IPC: A61K9/51 , A61K31/517 , A61K31/5377
Abstract: 본발명은폐암치료향상을위한제피티닙또는에를로티닙나노복합체에관한것으로보다상세하게는폐암치료에이용하는제피티닙(Gefitinib) 또는에를로티닙(Erlotinib)을나노물질에부착한것을특징으로하는폐암치료향상을위한제피티닙또는에를로티닙나노복합체를제공한다.
Abstract translation: 本发明涉及用于增强肺癌治疗的吉非替尼或厄洛替尼的纳米复合物，更具体地，涉及用于增强肺癌治疗的吉非替尼或厄洛替尼的纳米复合物，其中纳米复合物附着用于治疗肺癌的吉非替尼或厄洛替尼 纳米材料。
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7.发明公开
公开(公告)号：KR1020110047920A
公开(公告)日：2011-05-09
申请号：KR1020090104725
申请日：2009-10-31
Applicant: 숭실대학교산학협력단
CPC classification number: A61K33/38 , A61K39/39558 , A61K47/02 , A61K47/52 , B82Y5/00
Abstract: PURPOSE: A silver or gold nanoparticle used in carcinoma cells using intracellular inhalation and toxicity difference by surface charge is provided to be used as a probe. CONSTITUTION: A positively or negatively charged gold or silver nanoparticle is used as a drug delivery system and anticancer drug. The gold or silver nanoaprticle is used for minimizing cytotoxicity. The carcinoma cell is pulmonary carcinoma cell. The gold or silver carcinoma cells are used as a probe.
Abstract translation: 目的：使用细胞内吸入癌细胞中的银或金纳米颗粒，并通过表面电荷引起毒性差异作为探针。 构成：使用正或负电荷的金或银纳米颗粒作为药物递送系统和抗癌药物。 使用金或银纳米颗粒来最小化细胞毒性。 癌细胞是肺癌细胞。 金或银癌细胞用作探针。
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公开(公告)号：KR1020110024645A
公开(公告)日：2011-03-09
申请号：KR1020090082723
申请日：2009-09-02
Applicant: 숭실대학교산학협력단
Abstract: PURPOSE: A method for detecting the thermal stability of a self-assembled thin film in a ruthenium dye-sensitive solar cell is provided to offer a useful base for manufacture of a ruthenium dye-sensitive solar cell. CONSTITUTION: A method for detecting the thermal stability of a self-assembled thin film in a ruthenium dye-sensitive solar cell detects changes in infrared spectrum according to changes in the temperature of NCS or CN group included in ruthenium dye. The infrared spectrum is obtained by DRIFT(Diffuse Reflectance Infrared Fourier Transform) spectroscopy, and the ruthenium dye is selected from the group consisting of N719((Bu4N)2[Ru(dcbpyH)2-(NCS)2) N3 and ruthenium 505.
Abstract translation: 目的：提供一种用于检测钌染料敏感型太阳能电池中自组装薄膜的热稳定性的方法，为钌染料敏感型太阳能电池的制造提供了有用的基础。 构成：检测钌染料敏感型太阳能电池中自组装薄膜的热稳定性的方法根据钌染料中所含的NCS或CN组的温度变化来检测红外光谱的变化。 通过DRIFT（漫反射红外傅立叶变换）光谱获得红外光谱，钌染料选自N719（（Bu4N）2 [Ru（dcbpyH）2-（NCS）2）N3和钌505。
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公开(公告)号：KR1020170014929A
公开(公告)日：2017-02-08
申请号：KR1020150108986
申请日：2015-07-31
Applicant: 숭실대학교산학협력단
Abstract: 본발명은메티오닌을이용한 Cr(III)의검출방법에관한것으로, 보다상세하게는물과같은시료중에함유된 Cr(III) 이온을메티오닌과먼저반응시켜 Cr(III)을메티오닌으로둘러싼후 상기 Cr(III)-메티오닌복합체가금나노입자와결합하고금나노입자를응집시켜비색법, UV-vis 흡광법또는표면증강라만산란(SERS)법을통해시료중에함유된 Cr(III) 이온을 300 nM의검출한계로검출할수 있으며, 특히방해이온의영향없이선택적으로손쉽고간편하게증류수, 수돗물, 강물및 바닷물에함유된 Cr(III)을검출할수 있다.
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10.发明公开앱타머가 부착된 은나노입자 및 표면 증강 라만 분광법에 의한 서브나노 몰 단위의 오크라톡신 A의 검출 방법 无效通过使用APTAMER附着的银纳米颗粒和表面增强的拉曼散射法检测OCHRATOXIN A的亚纳米探测方法
公开(公告)号：KR1020150118848A
公开(公告)日：2015-10-23
申请号：KR1020140045017
申请日：2014-04-15
Applicant: 숭실대학교산학협력단 , 경희대학교 산학협력단
Abstract: 본발명은, 앱타머가부착된은나노입자및 표면증강라만분광법에의한서브나노몰 단위의오크라톡신 A의검출방법에관한것으로서, 검체및, 마이코톡신올리고뉴클레오티드앱타머가부착된금속나노입자를혼합하는단계; 상기혼합물을응집제로응집하는단계; 및상기응집물에대해표면증강라만산란을측정한후, 대조군의그것과비교하여마이코톡신포함여부를판단하는것을특징으로한다. 본발명은, 편리한방법으로 OTA를검출할수 있는빠르고비용효과적으로서브나노몰 수준의오크라톡신 A를검출할 수있는효과가있다.
Abstract translation: 通过使用适配子的银纳米颗粒和表面增强的拉曼光谱法检测亚纳摩尔单元的赭曲霉毒素A的方法包括以下步骤：将物体与真菌毒素寡核苷酸适体连接的金属纳米颗粒混合; 将混合物聚集成聚集体; 通过比较聚集体的表面增强拉曼与聚集体的表面增强拉曼后的对照组的表面增强拉曼进行比较来确定是否包含霉菌毒素。 根据本发明，可以通过方便的方法以低成本快速检测亚纳摩尔单元的赭曲霉毒素A。
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