안정한 피록시캄 주사액 조성물 및 그의 제조방법
    1.
    发明授权
    안정한 피록시캄 주사액 조성물 및 그의 제조방법 失效
    稳定的吡罗昔康注射液组合物及其制备方法

    公开(公告)号:KR1019920006911B1

    公开(公告)日:1992-08-22

    申请号:KR1019890008200

    申请日:1989-06-14

    Abstract: A stable piroxicam injection compsn.contains piroxicam as an effective ingredient, 1.1 - 1.2 mole of L-arginine or L-lysine (relative to 1 mole piroxicam) as a solubilizing agent, 15-25 W/V % of propylene glycol mixture and 1-2 W/V % of polyvinyl pyrrolidone. Also claimed is the prepn. of the compsn. which comprises dissolving piroxicam with L-arginine, L-lysine and propylene glycol in distilled water for injection, and adding polyvinyl pyrrolidone into the obtd. soln as a stabilizer. Piroxicam is useful as a nonsteroidal antiphlogistic analgesic.

    Abstract translation: 稳定的吡罗昔康注射剂含有炎痛喜糖作为有效成分,1.1-1.2摩尔L-精氨酸或L-赖氨酸(相对于1摩尔吡罗昔康)作为增溶剂,15-25W / V%的丙二醇混合物和1 -2W / V%的聚乙烯吡咯烷酮。 还声称是prepn。 的compsn。 其中包括将吡罗昔康与L-精氨酸,L-赖氨酸和丙二醇溶解在用于注射的蒸馏水中,并将聚乙烯吡咯烷酮加入到该溶液中。 soln作为稳定剂。 吡罗昔康作为非甾体类消炎止痛药有用。

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