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公开(公告)号：KR1020110134195A
公开(公告)日：2011-12-14
申请号：KR1020100054052
申请日：2010-06-08
Applicant: 아주대학교산학협력단
IPC: G01N33/53 , G01N33/564 , G01N33/68
Abstract: PURPOSE: A composition containing a formulation for measuring lactoferrin expression level is provided to ensure anti-inflammation and to prevent and treat diseases caused by allergen. CONSTITUTION: A method for providing information for diagnosing allergic rhinitis comprises: a step of preparing a sample from an individual; a step of measuring lactoferrin expression level from the sample; and a step of determining allergic rhinitis in case that the individual has less than 307ng/ml of lactoferrin. The allergic rhinitis is caused by dermatophagoides pteronyssinus(Dpt). The sample includes tissue, cells, whole blood, plasma, spittle, or urine. A composition for diagnosing allergic rhinitis contains a formulation for measuring lactoferrin expression level.
Abstract translation: 目的：提供含有用于测定乳铁蛋白表达水平的制剂的组合物，以确保抗炎和预防和治疗由过敏原引起的疾病。 构成：提供用于诊断过敏性鼻炎的信息的方法包括：从个体制备样品的步骤; 从样品测量乳铁蛋白表达水平的步骤; 在个体具有少于307ng / ml的乳铁蛋白的情况下，确定过敏性鼻炎的步骤。 过敏性鼻炎是由皮肤癣菌（Dpt）引起的。 样品包括组织，细胞，全血，血浆，唾液或尿液。 用于诊断过敏性鼻炎的组合物含有用于测定乳铁蛋白表达水平的制剂。
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公开(公告)号：KR1020130023053A
公开(公告)日：2013-03-07
申请号：KR1020120058842
申请日：2012-05-31
Applicant: 아주대학교산학협력단
Abstract: PURPOSE: A diagnostic kit for allergy to antibiotics, capable of containing an antibiotics-human serum protein conjugate is provided to check an allergy to antibiotics in advance, and to prevent damage due to allergy. CONSTITUTION: A diagnostic kit for an allergy to antibiotics, capable of containing an antibiotics-human serum protein conjugate is used for identifying the allergy development to antibiotics. The antibiotics include cephalosporin-based antibiotics or quinolone-based antibiotics. The cephalosporin-based antibiotics are selected from a group consisting of cephathin, cephaloridin, cefotiam, cephapirin, cephcetrile, cefazolin, ceftriaxone, cephaloglycin, cefaclor, cephradine, cefamandole, cefuroxim, ceftizoxime, cefotaxime, cefriaxone, ciprofloxacin, and cefoperazone. [Reference numerals] (AA) Inhibition ratio(%); (BB) Cefotiam- human serum albumin; (CC) Cefotiam; (DD) Ceftriaxone- human serum albumin; (EE) Ceftriaxone; (FF) Ceftizoxime- human serum albumin; (GG) Ceftizoxime; (HH) Ciprofloxacin- human serum albumin; (II) Human serum albumin; (JJ) Concentration of an inhibitor(ug/mL)
Abstract translation: 目的：提供能够含有抗生素 - 人血清蛋白结合物的抗生素过敏诊断试剂盒，以预防对抗生素的过敏，并防止因过敏引起的损伤。 组成：用于对抗生素过敏的诊断试剂盒，能够含有抗生素 - 人血清蛋白结合物，用于鉴定对抗生素的过敏发展。 抗生素包括基于头孢菌素的抗生素或基于喹诺酮的抗生素。 头孢菌素类抗生素选自由以下组成的组：头孢菌素，头孢吡肟，头孢匹胺，头孢哌酮，头孢哌酮，头孢曲松，头孢曲松，头孢克洛，头孢拉定，头孢噻肟，头孢呋辛，头孢唑肟，头孢噻肟，头孢曲松，环丙沙星和头孢哌酮。 （标号）（AA）抑制率（％） （BB）头孢司坦 - 人血清白蛋白; （CC）Cefotiam; （DD）头孢曲松 - 人血清白蛋白; （EE）头孢曲松; （FF）头孢唑肟 - 人血清白蛋白; （GG）头孢唑肟; （HH）环丙沙星 - 人体血清白蛋白; （二）人血清白蛋白; （JJ）抑制剂浓度（μg/ mL）
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Patent Agency Ranking
公开(公告)号：KR101468272B1
公开(公告)日：2014-12-02
申请号：KR1020120058842
申请日：2012-05-31
Applicant: 아주대학교산학협력단
Abstract: 본발명은항생제알레르기의발생여부를확인할수 있는항생제-인혈청단백질접합체, 상기항생제-인혈청단백질접합체가코팅된기판을포함하는항생제알레르기진단용단백질칩, 상기단백질칩 및표지된검출용물질을포함하는항생제알레르기진단용키트및 상기키트를이용하여항생제알레르기진단을위한정보를제공하는방법에관한것이다. 본발명의항생제-인혈청단백질접합체를이용할경우, 항생제에대하여알레르기반응을일으키는지의여부를사전에확인함으로써항생제알레르기로인한피해를사전에방지할수 있으므로, 보다안전한항생제치료에널리활용될수 있을것이다.
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公开(公告)号：KR101242797B1
公开(公告)日：2013-03-12
申请号：KR1020100054052
申请日：2010-06-08
Applicant: 아주대학교산학협력단
IPC: G01N33/53 , G01N33/564 , G01N33/68
Abstract: 본 발명은 락토페린 발현 수준 측정 제재를 포함하는 알러지성 비염 진단용 조성물 및 이를 포함하는 알러지성 비염 진단을 위한 정보제공방법에 관한 것이다. 본 발명의 조성물은 항염증 및 항알러지성 활성을 갖는 조성물로, 알러젠에 의해 유발되는 질환에 예방 및 치료를 위한 용도로 유용하게 사용될 수 있다.
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公开(公告)号：KR101799985B1
公开(公告)日：2017-11-21
申请号：KR1020160113087
申请日：2016-09-02
Applicant: 아주대학교산학협력단
Abstract: 본발명은스핑고신및 S1P을이용한중증천식의진단방법에관한것으로, 천식환자의뇨내스핑고신및 혈청의 S1P을측정하여아스피린과민성천식을진단하는방법에관한것이다. 본발명에따른뇨내스핑고신및 혈청내 S1P의바이오마커를이용한중증천식의내재형인아스피린과민성천식의진단기술은임상및 경제적으로이점이있으며, 치료제타겟발굴에유용하다.
Abstract translation: 本发明涉及严重哮喘的有鞘氨醇S1P和，如何测量nyonae S1P神经鞘胺醇及哮喘患者的血清诊断阿司匹林哮喘超敏反应诊断。 基本技术阿司匹林超敏反应型哮喘，重度哮喘与根据本发明的生物标志物的血清nyonae鞘氨醇S1P和诊断是在临床和经济的优点，它是在治疗靶标发现是有用的。
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公开(公告)号：KR1020120001916A
公开(公告)日：2012-01-05
申请号：KR1020100062545
申请日：2010-06-30
Applicant: 아주대학교산학협력단
CPC classification number: C12Q1/6883 , C12Q1/6837 , C12Q2600/112 , C12Q2600/156
Abstract: PURPOSE: An SNP gene set for diagnosing aspirin intolerant asthma(AIA) and a kit and a microarray comprising the same are provided to enhance AIA-specific expression. CONSTITUTION: An SNP gene set for diagnosing aspirin intolerant asthma(AIA) contains polynucleotides having 20-400 serial DNA sequences with 27th base which is mutated or a complementary polynucleotide thereof. A microarray for diagnosing AIA contains the SNP gene set. A kit for diagnosing AIA contains the SNP gene set. A method for providing information for diagnosing AIA comprises: a step of preparing DNA samples from an individual; and a step of determining 27th base among polynucleotides of sequence numbers 1-72 or complementary polynucleotide thereof.
Abstract translation: 目的：提供用于诊断阿司匹林不耐受性哮喘（AIA）的SNP基因和包含其的试剂盒和微阵列，以增强AIA特异性表达。 构成：用于诊断阿司匹林不耐受性哮喘（AIA）的SNP基因包含具有突变的第27位碱基的20-400个连续DNA序列的多核苷酸或其互补多核苷酸。 用于诊断AIA的微阵列包含SNP基因组。 用于诊断AIA的试剂盒含有SNP基因组。 用于提供用于诊断AIA的信息的方法包括：从个体制备DNA样品的步骤; 以及确定序列号1-72的多核苷酸之间的第27位碱基或其互补多核苷酸的步骤。
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公开(公告)号：KR1020120001917A
公开(公告)日：2012-01-05
申请号：KR1020100062546
申请日：2010-06-30
Applicant: 아주대학교산학협력단
CPC classification number: C12Q1/6883 , C12Q1/6837 , C12Q2600/112 , C12Q2600/156
Abstract: PURPOSE: An SNP gene set for diagnosing aspirin intolerant urticaria and a kit comprising the same are provided to diagnose and prevent aspirin intolerant urticaria. CONSTITUTION: An SNP gene set for diagnosing aspirin intolerant urticaria contains 20-100 serial DNA sequences containing 27th base which is mutated, or complementary polynucleotide thereof. A microarray for diagnosing aspirin intolerant urticaria contains the SNP gene set for diagnosing aspirin intolerant urticaria. A kit for diagnosing aspirin intolerant urticaria contains the SNP gene set.
Abstract translation: 目的：提供用于诊断阿司匹林不耐受性荨麻疹的SNP基因和包含其的试剂盒，用于诊断和预防阿司匹林不耐受性荨麻疹。 构成：用于诊断阿司匹林不耐受性荨麻疹的SNP基因包含20-100个连续的DNA序列，其包含突变的第27个碱基或其互补多核苷酸。 用于诊断阿司匹林不耐受性荨麻疹的微阵列包含用于诊断阿司匹林不耐受性荨麻疹的SNP基因。 用于诊断阿司匹林不耐受性荨麻疹的试剂盒含有SNP基因组。
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