-
公开(公告)号：KR101831636B1
公开(公告)日：2018-02-23
申请号：KR1020160014426
申请日：2016-02-04
Applicant: 원광대학교산학협력단
IPC: A61K31/704 , A61K31/7042 , A61K36/25 , A23L1/30
Abstract: 본발명은, 조엽오가피의잎에서분리동정된유효성분을함유하는비만을예방, 개선또는치료하는약학적조성물에관한것이다. (여기에서, 유효성분은올레산의 3-O-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranosyl-(1→2)-O-α-L-arabinopyranosides 임.)더욱상세하게는, 지방세포로의분화를억제하는효능, 지방세포의분화인자인 PPARγ와 C/EBPα의발현을억제하는효능및 AMPKα의인산화를유도하는효능을통해서, 비만을예방, 개선또는치료할수 있다.
-
公开(公告)号：KR101747412B1
公开(公告)日：2017-06-14
申请号：KR1020140133186
申请日：2014-10-02
Applicant: 원광대학교산학협력단
Abstract: 본발명은구글스테론을유효성분으로함유하는급성췌장염의예방, 개선또는치료를위한조성물에관한것이다. 본발명에따른조성물은몸무게에대한췌장중량비율, 급성췌장염으로인한췌장및 폐조직의손상, 췌장의호중구침윤, 혈청아밀라아제(amylase) 및리파아제(lipase)의활성및 염증성사이토카인의분비를억제함으로써, 급성췌장염의예방, 개선또는치료효능을제공할수 있다.
-
公开(公告)号：KR1020160102829A
公开(公告)日：2016-08-31
申请号：KR1020150025406
申请日：2015-02-23
Applicant: 원광대학교산학협력단
IPC: A61K31/357 , A23L1/30
CPC classification number: A61K31/357 , A23L33/10
Abstract: 본발명은오미자유래고미신 A를유효성분으로함유하는흑색종의예방, 개선또는치료를위한조성물에관한것이다더욱상세하게는고미신 A를 0.1~100 μM 함유하는흑색종의예방, 개선또는치료를위한조성물에관한것으로, 본발명에따른조성물은마우스유래전이성흑색종세포인 B16F10 세포주에서, 세포자멸사를유도하고, 이동성및 침윤성과같은전이능력을억제하며, 흑색종으로인한폐의전이를억제하는효능을보유하고있다.
Abstract translation: 本发明涉及一种用于预防，减轻或治疗黑素瘤的组合物，其包含源自中国五味子的戈希喜蛋白A作为活性成分，更具体地，涉及用于预防，减轻或治疗黑素瘤的组合物，其包含0.1-100M 根据本发明，作为小鼠来源的转移性黑素瘤细胞的B16F10细胞株中的组成诱导细胞凋亡，抑制移动能力和浸润等转移能力，保持抑制作用 由黑素瘤引起的肺转移。
-
4.发明公开
公开(公告)号：KR1020160070872A
公开(公告)日：2016-06-21
申请号：KR1020140177281
申请日：2014-12-10
Applicant: 원광대학교산학협력단
IPC: A61K36/734 , A61P1/00
CPC classification number: A61K36/734 , Y10S514/811
Abstract: 본발명은산사추출물을유효성분으로포함하는비알콜성지방간질환예방, 개선또는치료용조성물에관한것으로, 보다상세하게는산사추출물을유효성분으로포함하여지질축적으로인한간조직의변형및 지방축적을감소시키고, 혈중지질함량을감소시켜비알콜성지방간질환의예방또는치료에유용하게사용될수 있는비알콜성지방간질환예방, 개선또는치료용조성물에관한것이다.
Abstract translation: 本发明涉及含有山楂果实提取物作为活性成分的用于预防，改善或治疗非酒精性脂肪肝疾病的组合物。 更具体地，本发明涉及用于预防，改善或治疗非酒精性脂肪肝疾病的组合物。 本发明的组合物含有山楂果实提取物作为活性成分，因此脂肪蓄积和由于积累的脂质引起的肝组织转化降低，同时降低血脂水平。 因此，本发明的组合物可用于预防或治疗非酒精性脂肪性肝病。
-
公开(公告)号：KR1020160043202A
公开(公告)日：2016-04-21
申请号：KR1020140136757
申请日：2014-10-10
Applicant: 원광대학교산학협력단
IPC: A61K31/353 , A23L1/30
CPC classification number: A61K31/353 , A23L33/10 , A23V2002/00 , A23V2200/00
Abstract: 본발명은다이드제인을유효성분으로함유하는항노화기능성조성물에관한것으로, 더욱자세하게는 WI38 인간섬유아세포주에서 HO로유도한세포노화를억제하는조성물에관한것이다. 본발명에따른조성물은베타-갈락토시다아제(SA-β-galactosidase; SA-β-gal)를감소시키고, p16 pathway 및 mTOR pathway를조절함으로써세포노화를억제하는효능을보유하고있다.
Abstract translation: 本发明涉及抗衰老功能性组合物，其包含黄豆苷原作为活性成分，更具体地说，涉及用于抑制人成纤维细胞系WI38中的H_2O_2引起的细胞衰老的组合物。 根据本发明的组合物降低SA-β-半乳糖苷酶（SA-β-gal），控制p16途径和mTOR途径，从而抑制细胞衰老。
-
Patent Agency Ranking6.发明公开강황 및 천년초 추출물을 유효 성분으로 함유하는 구강 질환 예방, 개선 및 치료를 위한 조성물 有权用于治疗含有CURCUMA LONGA和OPUNTIA HUMIFUSA提取物的口腔疾病的组合物
公开(公告)号：KR1020140089728A
公开(公告)日：2014-07-16
申请号：KR1020130001498
申请日：2013-01-07
Applicant: 원광대학교산학협력단
IPC: A61K36/9066 , A61K36/33 , A61P1/02 , A61P1/00
CPC classification number: A61K36/9066 , A23L33/105 , A23V2250/21 , A61K36/33 , Y10S514/8995
Abstract: The present invention relates to a composition containing Curcuma longa and Opuntia humifusa extracts as active ingredients, wherein an extract extracted by mixing 80-120 parts by weight of Opuntia humifusa based on 100 parts by weight of Curcuma longa is contained as an active ingredient. The composition of the present invention has effects in controlling an increase in viruses in the oral cavity and preventing, alleviating, and treating stomatopathy.
Abstract translation: 本发明涉及含有姜黄和仙茅提取物作为活性成分的组合物，其中含有通过混合80-120重量份基于100重量份姜黄的胭脂红色油墨提取物的提取物作为活性成分。 本发明的组合物具有控制口腔病毒增加和预防，减轻和治疗口腔病变的效果。
-
公开(公告)号：KR1020130085578A
公开(公告)日：2013-07-30
申请号：KR1020120006441
申请日：2012-01-20
Applicant: 원광대학교산학협력단
Abstract: PURPOSE: A composition for prevention and treatment of acute pancreatitis containing Estern prickly pear as an active ingredient is provided to reduce the ratio of pancreas weight/body weight (PW/BW), the activation of blood serum amylase and lipase, inflammation of pancreas tissue, the extent of edema and necrosis, MPO activation, and the extent of the inflammation and edema of an inflammatory reaction promoting cytokine and a lung tissue. CONSTITUTION: A composition for prevention and treatment of acute pancreatitis includes Estern prickly pear extract as an active ingredient. The extract is extracted by using stems of Estern prickly pear. The solvent for the extraction of the extract is ethanol. Daily dose of the extract is 0.0001 to 500 mg/kg. Health functional food for prevention and alleviation of acute pancreatitis includes Estern prickly pear extract as an active ingredient.
Abstract translation: 目的：提供一种用于预防和治疗含有仙人掌作为活性成分的急性胰腺炎的组合物，用于减少胰腺重量/体重（PW / BW），血清淀粉酶和脂肪酶的活化，胰腺组织炎症的比例 ，水肿和坏死程度，MPO活化，以及促进细胞因子和肺组织的炎症反应的炎症和水肿程度。 构成：用于预防和治疗急性胰腺炎的组合物包括仙人掌提取物作为活性成分。 通过使用仙人掌茎提取提取物。 提取物的溶剂是乙醇。 提取物的日剂量为0.0001〜500mg / kg。 用于预防和缓解急性胰腺炎的健康功能食品包括仙人掌提取物作为活性成分。
-
8.发明公开
公开(公告)号：KR1020170093012A
公开(公告)日：2017-08-14
申请号：KR1020160014426
申请日：2016-02-04
Applicant: 원광대학교산학협력단
IPC: A61K31/704 , A61K31/7042 , A61K36/25 , A23L1/30
Abstract: 본발명은, 글리코시드 St-E2(Glycoside St-E2)를유효성분으로함유하는비만을예방, 개선또는치료하는약학적조성물에관한것이다. (여기에서, 글리코시드 St-E2는 Olean-12-en-28-oic acid, 3-[(O-β-D-galactopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranosyl)oxy]- 및 (3β)-(9CI) 성분을지칭함.) 더욱상세하게는, 지방세포로의분화를억제하는효능, 지방세포의분화인자인 PPARγ와 C/EBPα의발현을억제하는효능및 AMPKα의인산화를유도하는효능을통해서, 비만을예방, 개선또는치료할수 있다.
Abstract translation: 本发明涉及用于预防，改善或治疗含有糖苷St-E2（糖苷St-E2）作为活性成分的肥胖症的药物组合物。 其中糖苷St-E2选自Olean-12-en-28-酸，3 - [（O-β-D-吡喃半乳糖基 - →3）] - α-L-吡喃阿拉伯糖基）氧基] - ，和（3β） - （9CI）中提到的成分）更具体而言，来抑制脂肪细胞的分化，脂肪细胞因子PPARγ和C的效果分化 通过诱导氧化刚的功效抑制和AMPKα的表达/EBPα功效，可以预防，改善或治疗肥胖。
-
9.发明公开인삼 및 여로의 혼합 추출물을 유효성분으로 포함하는 비만의 예방 또는 치료용 조성물 有权包含PANAX GINSENG和VERATRUM NIGRUM L的混合提取物的组合物，用于预防或治疗肥胖
公开(公告)号：KR1020140074560A
公开(公告)日：2014-06-18
申请号：KR1020120142643
申请日：2012-12-10
Applicant: 원광대학교산학협력단
IPC: A61K36/258 , A61K36/896 , A61P3/04 , A61P3/00
Abstract: The present invention relates to a composition containing a mixed extract of Panax ginseng C.A. Meyer and Veratrum nigrum to prevent or treat obesity. The mixed extract of Panax ginseng C.A. Meyer and Veratrum nigrum according to the present invention inhibits weight gain and an increase in white fat and reduces the level of total cholesterol, triglyceride, and LDL in the blood, thereby being able to be effectively used for preventing or treating obesity.
Abstract translation: 本发明涉及含有人参C.A.的混合提取物的组合物。 Meyer和Veratrum nigrum来预防或治疗肥胖。 人参C.A.的混合提取物 根据本发明的迈耶和藜芦抑制体重增加和白脂肪增加，并降低血液中总胆固醇，甘油三酯和LDL的水平，从而能够有效地用于预防或治疗肥胖症。
-
公开(公告)号：KR1020130089299A
公开(公告)日：2013-08-12
申请号：KR1020120010551
申请日：2012-02-02
Applicant: 원광대학교산학협력단
IPC: A61K31/03
Abstract: PURPOSE: A pharmaceutical containing alpha-pinene as an active ingredient for treating and preventing cellular inflammation and inflammatory bowel disease is provided to prevent, improve, and cure cellular inflammation and inflammatory bowel disease by inhibiting the production of cytokine promoting inflammation. CONSTITUTION: A pharmaceutical for treating and preventing cellular inflammation and inflammatory bowel disease contains alpha-pinene as an active ingredient. The cell relevant to the inflammatory bowel disease is human large intestine epithelial cell. The pharmaceutical suppresses the production of cytokine promoting inflammation. A health functional food for preventing and improving cellular inflammation and inflammatory bowel disease contains alpha-pinene as an active ingredient.
Abstract translation: 目的：提供含有α-蒎烯作为治疗和预防细胞炎症和炎症性肠病的活性成分的药物，以通过抑制细胞因子促进炎症的产生来预防，改善和治愈细胞炎症和炎症性肠病。 构成：治疗和预防细胞炎症和炎症性肠病的药物含有α-蒎烯作为活性成分。 与炎症性肠病有关的细胞是人类大肠上皮细胞。 药物抑制细胞因子促进炎症的产生。 用于预防和改善细胞炎症和炎症性肠病的健康功能食品含有α-蒎烯作为活性成分。
-
-
-
-
-
-
-
-
-
Search Results
38
records
(took 0.025 seconds)
