公开(公告)号：KR100777229B1

公开(公告)日：2007-11-28

申请号：KR1020060119226

申请日：2006-11-29

Applicant: 재단법인서울대학교산학협력재단

Inventor： 이인원 ,  정선요 ,  김정은 ,  윤성환

IPC: C12N1/14

Abstract: A method for economically mass-producing zearalenone is provided to obtain large amount of the zearalenone by removing a PKS 12 which synthesizes aurofusarin in the production pathways of the zearalenone. A Gibberella zeae mass-producing zearalenone is deposited as a deposition no. KCCM 10794P. A method for increasing the zearalenone production comprises a step of blocking the aurofusarin biosynthesis pathway of the Gibberella zeae by deleting a PKS12 gene. A method for mass-producing the zearalenone comprises a step of solid-culturing the strain.

Abstract translation: 提供了一种经济地生产玉米赤霉烯酮的方法，通过去除在玉米赤霉烯酮生产途径中合成香叶素的PKS 12来获得大量的玉米赤霉烯酮。 玉米赤霉菌大量生产玉米赤霉烯酮作为沉积物沉积。 KCCM 10794P。 增加玉米赤霉烯酮生产的方法包括通过缺失PKS12基因来阻断玉米赤霉病的aurofusarin生物合成途径。 批量生产玉米赤霉烯酮的方法包括固定培养菌株的步骤。