감 미숙과 추출물을 이용한 항염증용 조성물 및 아토피성 피부염 개선용 조성물
    4.
    发明公开
    감 미숙과 추출물을 이용한 항염증용 조성물 및 아토피성 피부염 개선용 조성물 有权
    抗肿瘤组合物和使用双酚KAKI的水果提取物的本地化合物的改进组合物

    公开(公告)号:KR1020140056192A

    公开(公告)日:2014-05-09

    申请号:KR1020140021196

    申请日:2014-02-24

    Abstract: The present invention discloses an anti-inflammation composition and an atopic dermatitis alleviation composition using an extract of immature fruits of Diospyros kaki. Specifically, disclosed are an anti-inflammation composition and an atopic dermatitis alleviation composition using an extract of immature fruits of Diospyros kaki, which have activity of inhibiting production of NO, PGE2, inflammatory cytokine, etc. in macrophages stimulated with LPS and inhibiting production of MDC and TARC in HaCaT cells which is a keratinocyte cell line processed with hIFN-γ and TNF-α.

    Abstract translation: 本发明公开了使用柿子未成熟果实的提取物的抗炎组合物和特应性皮炎减轻组合物。 具体地,公开了使用具有抑制LPS刺激的巨噬细胞中产生NO,PGE2,炎性细胞因子等的活性的Diospyros kaki的未成熟果实的提取物的抗炎组合物和特应性皮炎减轻组合物, HaCaT细胞中的MDC和TARC是用hIFN-γ和TNF-α处理的角质细胞细胞系。

    감 미숙과 추출물을 이용한 항염증용 조성물 및 아토피성 피부염 개선용 조성물
    5.
    发明公开
    감 미숙과 추출물을 이용한 항염증용 조성물 및 아토피성 피부염 개선용 조성물 有权
    抗肿瘤组合物和使用双酚KAKI的水果提取物的本地化合物的改进组合物

    公开(公告)号:KR1020140055375A

    公开(公告)日:2014-05-09

    申请号:KR1020120122087

    申请日:2012-10-31

    Abstract: The present invention discloses an anti-inflammatory composition and a composition for alleviation of atopic dermatitis using an extract from immature fruits of Diospyros kaki. Particularly, disclosed are an anti-inflammatory composition and a composition for alleviation of atopic dermatitis using an extract from immature fruits of Diospyros kaki, having the activity of inhibiting the generation of NO, PGE_2, inflammatory cytokines, etc. in LPS-stimulated macrophages and having the activity of inhibiting the generation of MDC and TARC in HaCaT cells which are a keratinocyte cell line treated with hIFN-gamma and TNF-alpha.

    Abstract translation: 本发明公开了一种抗炎组合物和一种用于使用来自柿子的未成熟果实的提取物来减轻特应性皮炎的组合物。 特别是公开了使用具有抑制LPS刺激的巨噬细胞中NO,PGE_2,炎性细胞因子等产生的活性的Diospyros kaki的提取物来减轻特应性皮炎的抗炎组合物和组合物, 具有抑制HaCaT细胞中产生MDC和TARC的活性,HaCaT细胞是用hIFN-γ和TNF-α处理的角质细胞细胞系。

    8-옥소-9-옥타데세노산을 이용한 항염증용 조성물
    9.
    发明公开
    8-옥소-9-옥타데세노산을 이용한 항염증용 조성물 有权
    使用8-氧代-9-十一碳烯酸的抗炎组合物

    公开(公告)号:KR1020160076111A

    公开(公告)日:2016-06-30

    申请号:KR1020140185865

    申请日:2014-12-22

    CPC classification number: A61K31/201

    Abstract: 본발명은넓미역추출물로부터분리된 8-옥소-9-옥타데세노산을이용한항염증용조성물을개시한다. 구체적으로본 발명은 LPS(lipopolysaccharide)로자극된대식세포에서 NO 생성억제활성, PGE생성억제활성, 염증성사이토카인(TNF-α및 IL-6) 생성억제활성그리고 iNOS 및 COX-2 발현억제활성을보이는 8-옥소-9-옥타데세노산을이용한항염증용조성물을개시한다.

    Abstract translation: 在本发明中公开的是使用从黄花松提取物中分离的8-氧代-9-十八烯酸的抗炎组合物。 具体地说,本发明中公开的是使用8-氧代-9-十八碳烯酸的抗炎组合物,其在用脂多糖(LPS)刺激的巨噬细胞中表现出NO产生抑制活性,PGE_2产生抑制活性,炎性细胞因子(TNF-α和 IL-6)抑制活性,以及​​iNOS和COX-2表达的抑制活性。

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