公开(公告)号：KR1020140049757A

公开(公告)日：2014-04-28

申请号：KR1020120115967

申请日：2012-10-18

Applicant: 전남대학교병원

Inventor： 고정태 ,  정병철 ,  배인호 ,  최혁 ,  허성웅

IPC: A61K38/17 ,  A61K38/16 ,  A61K48/00 ,  A61P19/00

CPC classification number: A61K38/17 ,  C07K14/435 ,  Y10S514/825

Abstract: The present invention relates to a composition for bone regeneration and, more specifically, to a composition for bone regeneration which has a significantly improved bone regeneration effect only by using a small amount of bone morphogenetic protein-2 (BMP-2) which is expensive. The composition comprises BMP-2 and cartilage oligomeric matrix protein-angiopoietin-1 (COMP-Ang 1) as active ingredients.

Abstract translation: 本发明涉及一种用于骨再生的组合物，更具体地，涉及一种骨再生用组合物，其仅通过使用少量昂贵的骨形态发生蛋白-2（BMP-2）而具有显着改善的骨再生效果。 该组合物包含BMP-2和软骨低聚基质蛋白 - 血管生成素-1（COMP-Ang 1）作为活性成分。