公开(公告)号：KR1020110126227A

公开(公告)日：2011-11-23

申请号：KR1020100045781

申请日：2010-05-17

Applicant: 전남대학교산학협력단

Inventor： 홍영진 ,  최현일 ,  조경오 ,  박상익 ,  이준행

IPC: A61K39/112 ,  A61K39/02 ,  A61P37/00 ,  A61P43/00

CPC classification number: Y02A50/482 ,  Y02A50/484 ,  A61K39/0275 ,  A61K2039/522 ,  Y10S424/826

Abstract: PURPOSE: A pharmaceutical vaccine composition for fowl typhoid and a feed composition for preventing fowl typhoid are provided to induce prepare antibiotics and to effectively prevent or treat fowl typhoid. CONSTITUTION: A pharmaceutical vaccine composition for fowl typhoid contains ppGpp(guanosine 5'-diphosphate 3'-diphosphate)-deletion mutant Salmonella Gallinarum. The strain contains inactivated relA gene, spoT gene encoding ppGpp synthase, or activated relA gene and spoT gene. A feed composition for preventing fowl typhoid contains the ppGpp-deletion mutant Salmonella Gallinarum. The composition is manufactured in the form of a tablet, pill, powder, granule, capsule, suspension, emulsion, or syrup.

Abstract translation: 目的：提供用于禽类伤寒和用于预防家禽伤寒的饲料组合物的药物疫苗组合物，以诱导制备抗生素并有效预防或治疗家禽伤寒。 构成：用于禽类伤寒的药物疫苗组合物含有ppGpp（鸟苷5'-二磷酸3'-二磷酸）缺失突变体沙门氏菌（Salmonella Gallinarum）。 该菌株含有灭活的relA基因，编码ppGpp合酶的spoT基因，或活化的relA基因和spoT基因。 用于防止禽类伤寒的饲料组合物含有ppGpp缺失突变体沙门氏菌（Salmonella Gallinarum）。 组合物以片剂，丸剂，粉剂，颗粒剂，胶囊剂，悬浮液，乳剂或糖浆剂的形式制备。