公开(公告)号：KR1020080024868A

公开(公告)日：2008-03-19

申请号：KR1020060089576

申请日：2006-09-15

Applicant: 전남대학교산학협력단

Inventor： 박광성 ,  안규윤 ,  한호재

IPC: A61K38/17 ,  A61P15/00

Abstract: Water channel proteins aquaporins which participate in water movement are provided to promote secretion of vaginal lubricating liquid. A vaginal lubricant is also provided to promote secretion of vaginal lubricating liquid by modulating expressions of the water channel proteins. A vaginal lubricant for promoting secretion of vaginal lubricating liquid modulates the expressions of water channel proteins aquaporins including aquaporin-1, aquaporin-2, aquaporin-3 and aquaporin-8, wherein the aquaporin-1 is expressed in capillary blood vessel, venule and smooth muscle in vaginal tissue, and the aquaporin-2 and aquaporin-3 are expressed in vaginal tissue epithelial cytoplasm.

Abstract translation: 提供参与水运动的水通道蛋白质水通道蛋白，以促进阴道润滑液的分泌。 还提供阴道润滑剂以通过调节水通道蛋白的表达来促进阴道润滑液的分泌。 用于促进阴道润滑液分泌的阴道润滑剂调节水通道蛋白水通道蛋白的表达，包括水通道蛋白1，水通道蛋白2，水通道蛋白3和水通道蛋白-8，其中水通道蛋白-1在毛细血管，小静脉和平滑肌中表达 肌肉在阴道组织中，水通道蛋白2和水通道蛋白-3在阴道组织上皮细胞质中表达。