公开(公告)号：KR101872126B1

公开(公告)日：2018-08-02

申请号：KR1020160166434

申请日：2016-12-08

Applicant: 전북대학교산학협력단

Inventor： 김은미 ,  김시라 ,  최미숙 ,  함준석 ,  임현아 ,  박성철 ,  정영숙 ,  최영재 ,  이동혁 ,  김화정

IPC: D21H17/63 ,  D21H17/37 ,  D21H17/67 ,  D21H21/08 ,  D21H21/10

Abstract: 본발명은보존성이향상된배접한지의제조방법에관한것으로서, 특히보존성뿐만아니라인장강도, 내절도및 백색도에대한물성이우수한배접한지를제조할수 있는보존성이향상된배접한지의제조방법에관한것으로서, 닥펄프에분산제를투입한상태에서고해공정을거친후 초지및 건조하여제조되고, 상기닥펄프 100중량부에패각분말 5~15중량부를혼합한상태에서고해공정을거치는것을특징으로한다.

公开(公告)号：KR100802010B1

公开(公告)日：2008-02-12

申请号：KR1020060060859

申请日：2006-06-30

Applicant: 전북대학교산학협력단

Inventor： 정환정 ,  김은미

IPC: A61K8/25

CPC classification number: A61K51/02 ,  A61K51/1217 ,  B82Y5/00

Abstract: Disclosed herein are a technetium-labeled tin nano- colloid and a method of preparing the same. The colloid is prepared by mixing a solution of radioactive technetium or a compound thereof with a solution containing tin or a compound thereof, sodium or a compound thereof, poloxamer and polyvinylpyrrolidone. The colloid, as a nano-sized particle allowing lymphatic migration, is very easily prepared, is suitably restricted to a uniform size, and has potential for use as a radiopharmaceutical in nuclear medicine, which is very useful as a radioactive tracer for identifying sentinel nodes, such as axillary lymph nodes in breast cancer.

公开(公告)号：KR1020080002190A

公开(公告)日：2008-01-04

申请号：KR1020060060859

申请日：2006-06-30

Applicant: 전북대학교산학협력단

Inventor： 정환정 ,  김은미

IPC: A61K8/25

CPC classification number: A61K51/02 ,  A61K51/1217 ,  B82Y5/00

Abstract: Tc(technetium)-99m nano tin colloid is provided to improve in vivo stability and biocompatibility, so that it is useful for obtaining nuclear medicine image of lymphatic system and screening sentinel lymph nodes of tumor such as axillary lymph nodes. The Tc-99m nano tin colloid is prepared by mixing radioactive technetium such as 99mTc or its compound solution with a solution containing tin or its compound, sodium or its compound, poloxamer and polyvinylpyrrolidone, wherein the tin has the general formula of SnX2 in which X is halogen atom, acetate, sulfate, oxalate or succinate; the nano colloid has the particle size of 10-30 nm; and the technetium nano tin colloid further comprises phosphate buffer and a pH regulating agent including sodium bicarbonate.

Abstract translation: 提供Tc（锝）-99m纳米锡胶体，以提高体内稳定性和生物相容性，有利于获得淋巴系统的核医学图像和筛选腋窝淋巴结肿瘤前哨淋巴结。 通过将放射性锝如99mTc或其化合物溶液与含锡或其化合物，钠或其化合物，泊洛沙姆和聚乙烯吡咯烷酮的溶液混合，制备Tc-99m纳米锡胶体，其中锡具有通式SnX2，其中X 是卤素原子，乙酸盐，硫酸盐，草酸盐或琥珀酸盐; 纳米胶体的粒径为10-30nm; 并且锝纳米锡胶体还包括磷酸盐缓冲液和包括碳酸氢钠的pH调节剂。