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公开(公告)号：KR101663550B1
公开(公告)日：2016-10-07
申请号：KR1020140070526
申请日：2014-06-11
Applicant: 조선대학교산학협력단
IPC: A61K31/194 , A23L1/30
Abstract: 본발명은주석산을유효성분으로포함하는고혈압예방또는치료용약학적조성물및 고혈압예방또는개선용건강기능식품관한것으로, 구체적으로본 발명의유효성분인주석산은안지오텐신 I 전환효소(angiotensin I converting enzyme; ACE)의활성을저해하여혈관수축을억제하며, 세포독성이거의나타나지않으므로고혈압의예방또는치료용약학조성물및 고혈압예방또는개선용건강기능식품으로서유용하게사용될수 있다.
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公开(公告)号：KR1020160116989A
公开(公告)日：2016-10-10
申请号：KR1020150045511
申请日：2015-03-31
Applicant: 조선대학교산학협력단
Abstract: 본발명은솔잎착즙분말을유효성분으로포함하는고콜레스테롤혈증의예방, 개선또는치료용조성물에관한것이다. 보다상세하게는솔잎의수분을탈수한후, 열수또는아임계추출등의추출법으로추출하지않고, 녹즙기를이용하여착즙하여얻은생즙을동결건조하여분말화한솔잎착즙분말을유효성분으로포함하는고콜레스테롤혈증의예방, 개선또는치료용조성물에관한것이다. 본발명의솔잎착즙분말은고혈압전단계대상자의혈중총콜레스테롤(TC) 및저밀도지질단백질콜레스테롤(LDL-C)을감소시키고, 고밀도지질단백질콜레스테롤(HDL-C)을증가시키는효과가있는것이다.
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公开(公告)号：KR101649895B1
公开(公告)日：2016-08-22
申请号：KR1020140194736
申请日：2014-12-31
Applicant: 조선대학교산학협력단
Abstract: 본발명은발효현미슬러리를유효성분으로포함하는기능성음료및 이의제조방법에관한것이다. 상세하게는현미와누룩을이용하여 3단계발효과정을수행하고, 상기단계에서생성된침전물을물로희석하여채로거른현미발효액을농축하는방법으로제조하는발효현미슬러리의제조방법에관한것이다. 본발명의제조방법에의해제조된발효현미슬러리는소화불량의원인인장내유해균에대한항균활성뿐만아니라항산화활성이우수하다. 따라서장 활성에도움을줄 수있는건강기능성음료또는식품으로제공하는것이가능하다.
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公开(公告)号：KR101427384B1
公开(公告)日：2014-08-07
申请号：KR1020130026278
申请日：2013-03-12
Applicant: 조선대학교산학협력단
IPC: A23L1/30 , A61K31/185 , A61P7/02
CPC classification number: A23L33/10 , A23V2002/00 , A23V2200/326 , A61K31/185
Abstract: The present invention relates to a polyacrylic acid macromolecule having antithrombotic activity and to uses thereof. According to the present invention, when the polyacrylic acid macromolecules is used as an antithrombotic, blood clots in blood are degraded and removed. Consequently, factors for regenerating blood clots can be basically removed. Moreover, when blood is treated with the polyacrylic acid to be stored, substances, which coagulate blood, are removed at the starting point. Therefore, the polyacrylic acid macromolecule having antithrombotic activity can prevent blood coagulation and be used for developing artificial blood powder.
Abstract translation: 本发明涉及具有抗血栓形成活性的聚丙烯酸高分子及其应用。 根据本发明，当使用聚丙烯酸大分子作为抗血栓形成时，血液中的血块被降解和除去。 因此，可以基本上除去血块再生的因素。 此外，当用待储存的聚丙烯酸处理血液时，凝结血液的物质在起始点被去除。 因此，具有抗血栓活性的聚丙烯酸高分子可以防止血液凝结，并用于开发人造血粉。
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公开(公告)号：KR101427381B1
公开(公告)日：2014-08-07
申请号：KR1020130026277
申请日：2013-03-12
Applicant: 조선대학교산학협력단
CPC classification number: A23L33/10 , A23V2002/00 , A23V2200/30 , A61K31/19
Abstract: The present invention relates to a protocatechuic acid derivative having an antithrombotic activity and to a use thereof. An antithrombotic pharmaceutical composition according to the present invention can be applied to common beverages, dietary supplements, or medicine, thus is expected to be able to prevent and treat diseases involving thrombopoiesis such as arteriosclerosis, cerebral hemorrhage, stroke, or cerebral infarction.
Abstract translation: 本发明涉及具有抗血栓形成活性的原儿茶酸衍生物及其应用。 根据本发明的抗血栓药物组合物可以应用于普通饮料，膳食补充剂或药物，因此预期能够预防和治疗涉及血小板生成（例如动脉硬化，脑出血，中风或脑梗塞）的疾病。
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Patent Agency Ranking
公开(公告)号：KR101627546B1
公开(公告)日：2016-06-07
申请号：KR1020140168367
申请日：2014-11-28
Applicant: 조선대학교산학협력단
IPC: A23L1/30 , A61K31/192 , A61P3/04 , C12N9/20
CPC classification number: A23L33/10 , A61K31/00 , A61K31/192 , C12N9/20 , Y10S435/853
Abstract: 본발명은리파아제저해활성을갖는프로토카테큐산유도체및 이의용도에관한것으로, 본발명에따른리파아제저해활성을갖는조성물은통상의음료, 건강보조식품또는의약품에적용할수 있으므로비만의예방, 개선또는치료에큰 효과를나타낼수 있을것이다.
Abstract translation: 本发明涉及具有脂肪酶抑制活性的原儿茶酸衍生物; 并使用它们。 根据本发明，具有脂肪酶抑制活性的组合物可以用于普通饮料，健康补充食品或药物，因此可以对预防，减轻或治疗肥胖有很大的影响。 用于预防或减轻肥胖症的健康食品组合物含有原儿茶酸衍生物或其盐作为活性成分。
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7.发明授权디하이드로아비어트산 또는 코문산을 유효성분으로 함유하는 고혈압 예방 또는 치료용 약학 조성물 및 건강식품 조성물 有权用于预防或治疗包含脱氢胆酸或通用酸作为有效成分的高血压的PHAMACEUTICAL AND HEALTH FOOD COMPOSION
公开(公告)号：KR101424032B1
公开(公告)日：2014-08-01
申请号：KR1020130040162
申请日：2013-04-12
Applicant: 조선대학교산학협력단
IPC: A23L1/30 , A61K31/192 , A61P9/12
CPC classification number: A23L33/105 , A23V2002/00 , A23V2200/3262 , A61K31/192
Abstract: According to the present invention, fractions derived from pine leaves with an inhibitory activity on an angiotensin converting enzyme are selected, and dehydroabietic acid and communic acid are identified by identifying structures among the selected materials with optimum activity. Provided are a health promotion food composition comprising dehydroabietic acid or communic acid as active ingredients for preventing or curing hypertension, a pharmaceutical composition for preventing or curing hypertension, an angiotensin converting enzyme inhibitor, and a pharmaceutical composition for preventing or curing vascular diseases. According to the present invention, dehydroabietic acid or communic acid derived from pine leaves has angiotensin converting enzyme inhibitory activity, and can be provided as a useful composition for consumer`s health. Since a method for extracting and segmenting is provided specifically in the present invention, the materials with excellent activity which is abundantly contained in pine leaves can be used as an economical raw material with a high function.
Abstract translation: 根据本发明，选择从对血管紧张素转换酶具有抑制活性的松叶衍生的馏分，通过鉴定所选材料中具有最佳活性的结构来鉴定脱氢松香酸和通酸。 提供了包含脱氢枞酸或通讯酸作为预防或治疗高血压的有效成分的健康促进食品组合物，用于预防或治疗高血压的药物组合物，血管紧张素转换酶抑制剂和用于预防或治疗血管疾病的药物组合物。 根据本发明，脱氢枞酸或衍生自松叶的通讯酸具有血管紧张素转化酶抑制活性，可作为消费者健康的有用组合物提供。 由于在本发明中具体提供了提取和分割方法，所以可以将作为具有高功能性的经济原料用作松果中大量含有的具有优异活性的材料。
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公开(公告)号：KR1020160082147A
公开(公告)日：2016-07-08
申请号：KR1020140194736
申请日：2014-12-31
Applicant: 조선대학교산학협력단
Abstract: 본발명은발효현미슬러리를유효성분으로포함하는기능성음료및 이의제조방법에관한것이다. 상세하게는현미와누룩을이용하여 3단계발효과정을수행하고, 상기단계에서생성된침전물을물로희석하여채로거른현미발효액을농축하는방법으로제조하는발효현미슬러리의제조방법에관한것이다. 본발명의제조방법에의해제조된발효현미슬러리는소화불량의원인인장내유해균에대한항균활성뿐만아니라항산화활성이우수하다. 따라서장 활성에도움을줄 수있는건강기능성음료또는식품으로제공하는것이가능하다.
Abstract translation: 本发明涉及包含发酵的糙米浆作为活性成分的功能饮料及其制备方法。 特别地，本发明涉及一种生产发酵糙米浆料的方法，其中通过使用糙米和酵母进行三步发酵程序，并且通过三步发酵程序产生的沉淀物被水稀释， 因此以浓缩由筛子过滤的糙米发酵液体的方式生产发酵的糙米浆料。 通过本发明的方法生产的发酵糙米浆料，对于引起消化不良的肠道有害细菌，具有优异的抗菌活性，而且具有优异的抗氧化活性。 因此，可以提供发酵的糙米浆料作为能够帮助肠道活动的健康功能饮料或食品。
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公开(公告)号：KR1020150142198A
公开(公告)日：2015-12-22
申请号：KR1020140070526
申请日：2014-06-11
Applicant: 조선대학교산학협력단
IPC: A61K31/194 , A23L1/30
CPC classification number: A61K31/194 , A23L33/10 , A23V2002/00 , A23V2200/30
Abstract: 본발명은주석산을유효성분으로포함하는고혈압예방또는치료용약학적조성물및 고혈압예방또는개선용건강기능식품관한것으로, 구체적으로본 발명의유효성분인주석산은안지오텐신 I 전환효소(angiotensin I converting enzyme; ACE)의활성을저해하여혈관수축을억제하며, 세포독성이거의나타나지않으므로고혈압의예방또는치료용약학조성물및 고혈압예방또는개선용건강기능식품으로서유용하게사용될수 있다.
Abstract translation: 本发明涉及用于预防或缓解包含酒石酸作为活性成分的高血压药物组合物和用于预防或缓解高血压的健康功能食品。 具体地说，作为本发明的活性成分的酒石酸通过抑制血管紧张素I转化酶（ACE）的活性抑制血管收缩，几乎不显示细胞毒性，因此可以有效地用作预防或缓解高血压的药物组合物， 用于预防或缓解高血压的健康功能食品。
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