-
公开(公告)号:KR100877151B1
公开(公告)日:2009-01-07
申请号:KR1020070067150
申请日:2007-07-04
Applicant: 충남대학교산학협력단
Abstract: A cell penetrating fusion protein Tat-ref-1, a gene coding the fusion protein Tat-ref-1, an expression vector containing the gene, the transformed E. coli, and a pharmaceutical composition containing the fusion protein Tat-ref-1 are provided to obtain a composition for treating the inflammation disease. A cell penetrating fusion protein Tat-ref-1 is the fusion protein that the human oxidation reduction factor-1 protein is fused with the protein transduction domain of the Tat protein, and is represented by the sequence number 1. Preferably the gene coding the fusion protein Tat-ref-1 is represented by the sequence number 4. The E. coli transformed by the expression vector containing the gent is deposited (deposition number KCTC-11139BP).
Abstract translation: 编码融合蛋白Tat-ref-1的基因的细胞穿透融合蛋白Tat-ref-1,含有该基因的表达载体,转化的大肠杆菌以及含有融合蛋白Tat-ref-1的药物组合物是 提供用于获得用于治疗炎症疾病的组合物。 细胞穿透融合蛋白Tat-ref-1是人类氧化还原因子-1蛋白与Tat蛋白的蛋白转导结构域融合的融合蛋白,由序列号1表示。优选地,编码融合蛋白的基因 蛋白质Tat-ref-1由序列号4表示。由含有绅士的表达载体转化的大肠杆菌被沉积(沉积编号KCTC-11139BP)。
-
-
公开(公告)号:KR102050759B1
公开(公告)日:2019-12-02
申请号:KR1020180104423
申请日:2018-09-03
Applicant: 충남대학교산학협력단
IPC: A63B29/08 , A45B3/04 , H01L31/042
-
-