항염증 활성을 갖는 세포투과성 산화환원인자-1 융합단백질
    1.
    发明授权
    항염증 활성을 갖는 세포투과성 산화환원인자-1 융합단백질 有权
    具有抗炎活性的细胞透性氧化还原因子-1融合蛋白

    公开(公告)号:KR100877151B1

    公开(公告)日:2009-01-07

    申请号:KR1020070067150

    申请日:2007-07-04

    Abstract: A cell penetrating fusion protein Tat-ref-1, a gene coding the fusion protein Tat-ref-1, an expression vector containing the gene, the transformed E. coli, and a pharmaceutical composition containing the fusion protein Tat-ref-1 are provided to obtain a composition for treating the inflammation disease. A cell penetrating fusion protein Tat-ref-1 is the fusion protein that the human oxidation reduction factor-1 protein is fused with the protein transduction domain of the Tat protein, and is represented by the sequence number 1. Preferably the gene coding the fusion protein Tat-ref-1 is represented by the sequence number 4. The E. coli transformed by the expression vector containing the gent is deposited (deposition number KCTC-11139BP).

    Abstract translation: 编码融合蛋白Tat-ref-1的基因的细胞穿透融合蛋白Tat-ref-1,含有该基因的表达载体,转化的大肠杆菌以及含有融合蛋白Tat-ref-1的药物组合物是 提供用于获得用于治疗炎症疾病的组合物。 细胞穿透融合蛋白Tat-ref-1是人类氧化还原因子-1蛋白与Tat蛋白的蛋白转导结构域融合的融合蛋白,由序列号1表示。优选地,编码融合蛋白的基因 蛋白质Tat-ref-1由序列号4表示。由含有绅士的表达载体转化的大肠杆菌被沉积(沉积编号KCTC-11139BP)。

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