公开(公告)号：KR101433049B1

公开(公告)日：2014-10-14

申请号：KR1020130085609

申请日：2013-07-19

Applicant: 충남대학교산학협력단

Inventor： 김민규 ,  이지혜 ,  김근중 ,  김은영 ,  박강선 ,  한길우 ,  이경본

IPC: C12N5/10 ,  C12N15/12 ,  A01K67/027 ,  G01N33/15

Abstract: The present invention relates to a method for manufacturing an animal model in which Parkinson′s disease related to the expression of DJ-1 gene is induced, an animal model manufactured by the same, and a method for judging the effect of a treatment candidate substance or a medicine of Parkinson′s disease by using the animal model. According to the present invention, in a research of a research model for treating Parkinson′s disease and a medicine for treating Parkinson′s disease, not only is difference between a normal tissue and a Parkinson′s disease expressing tissue biochemically compared, but also substances applicable as a medicine for Parkinson′s disease is detected by using the animal model to quantitively compare and judge the effect.

Abstract translation: 本发明涉及一种制造其中诱导与DJ-1基因的表达相关的帕金森病的动物模型的制造方法，以及由该方法制造的动物模型以及用于判断治疗候选物质的作用的方法 或使用动物模型的帕金森病药物。 根据本发明，在用于治疗帕金森病的研究模型和治疗帕金森病的药物的研究中，不仅正常组织与表达组织的帕金森病之间的差异在生物化学上比较，而且 通过使用动物模型量化比较和判断效果，可以检测到适用于帕金森病药物的物质。

公开(公告)号：KR101390536B1

公开(公告)日：2014-05-07

申请号：KR1020130033861

申请日：2013-03-28

Applicant: 충남대학교산학협력단 ,  전라북도 임실군(임실군 농업기술센터장)

Inventor： 김민규 ,  박연배 ,  한길우 ,  이준헌 ,  이경본 ,  장옥 ,  이기곤 ,  정일윤 ,  이성구

IPC: A01K67/027 ,  C12Q1/68 ,  A61D19/04

CPC classification number: A01K67/0275 ,  A61D19/04 ,  C12Q1/683 ,  C12Q2600/156

Abstract: The present invention provides a model and technology which selects a high capacity impotent cow having excellent heredity ability and collects eggs in vivo so as to enable mass propagation of excellent fertilized eggs by biotechnology technique, embryo transfer technology, etc., thereby acquiring, preserving, and maintaining outstanding genetic resources of hanwoo (Korean native cattle) in farm, and moreover, a high-quality meat production system is prepared so as to increase recessed hanwoo breeding farms and ensure competitiveness of hanwoo which is differentiated to imported meat.

Abstract translation: 本发明提供一种模型和技术，其选择具有优异遗传能力的高容量无能奶牛，并在体内收集鸡蛋，以便通过生物技术，胚胎移植技术等能够大量繁殖优质受精卵，从而获得，保存， 并在农场保持韩国优秀遗传资源，并制定优质的肉类生产系统，以增加农业部门的繁荣农业，确保与进口肉类不同的hanwoo的竞争力。

公开(公告)号：KR101943158B1

公开(公告)日：2019-01-28

申请号：KR1020160117142

申请日：2016-09-12

Applicant: 충남대학교산학협력단

Inventor： 김민규 ,  이지혜 ,  김근중 ,  김은영 ,  박강선 ,  한길우 ,  이보명

IPC: C12N15/873 ,  A01K67/027 ,  A61D19/04