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公开(公告)号：KR1020120120545A
公开(公告)日：2012-11-02
申请号：KR1020110038157
申请日：2011-04-25
Applicant: 충남대학교산학협력단
IPC: A61K31/12 , A61K31/045 , A61P19/10 , A61P19/00
Abstract: PURPOSE: A composition containing xanthohumol is provided to promote differentiation of osteoclast and to treat bone diseases. CONSTITUTION: A composition for preventing or treating osteoclast differentiation contains xanthohumol as an active ingredient. The composition contains xanthohumol and bone resorption inhibitor as an active ingredient. The bone absorption inhibitor is bisphosphonate, estrogen, calcitonin, vitamin D, calcium, fluoride, anabolic steroid or parathyroid hormone. A health functional food for preventing or treating osteoporosis contains xanthohumol as an active ingredient. The health functional food includes drink, meat, sausage, bread, candy, snack, noodle, ice cream, soup, isotonic drink, alcohol beverage, or vitamin complex.
Abstract translation: 目的：提供含有黄腐酚的组合物，以促进破骨细胞的分化和治疗骨骼疾病。 构成：用于预防或治疗破骨细胞分化的组合物含有黄单胞菌素作为活性成分。 该组合物含有黄单胞菌素和骨吸收抑制剂作为活性成分。 骨吸收抑制剂是二膦酸盐，雌激素，降钙素，维生素D，钙，氟化物，合成代谢类固醇或甲状旁腺激素。 用于预防或治疗骨质疏松症的保健功能食品含有黄腐酚醇作为活性成分。 健康功能食品包括饮料，肉类，香肠，面包，糖果，小吃，面条，冰淇淋，汤，等渗饮料，酒精饮料或维生素复合物。
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公开(公告)号：KR101325094B1
公开(公告)日：2013-11-06
申请号：KR1020110019281
申请日：2011-03-04
Applicant: 충남대학교산학협력단 , (주)머쉬토피아
Abstract: 본 발명은 아토피 피부염의 예방 또는 치료용 조성물에 관한 것으로서, 더욱 상세하게는 아토피 피부염과 같은 각종 피부질환의 증세를 치료 또는 경감시키는 활성이 탁월한 새송이버섯 추출물에 관한 것이다.
본 발명에서는 상기 새송이버섯 추출물이 아토피 피부염에서 증가된다고 알려진 사이토카인 및 단백질인 TARC/CCL17, MDC/CCL22, CTACK/CCL27, ICAM-1 등의 발현을 감소시키는 것을 나타냄으로, 상기 추출물이 아토피 피부염의 치료제로 사용될 수 있음을 확인할 수 있다.-
公开(公告)号：KR1020120100414A
公开(公告)日：2012-09-12
申请号：KR1020110019281
申请日：2011-03-04
Applicant: 충남대학교산학협력단 , (주)머쉬토피아
Abstract: PURPOSE: A composition for preventing or treating atopic dermatitis which contains pine mushroom extracts is provided to reduce expression of cytokine and TARC/CCL17, MDC/CCL22, CTACK/CCL27,and ICAM-1 which are proteins. CONSTITUTION: A composition for preventing or treating atopic dermatitis contains pine mushroom extracts as active ingredient. The organic solvent is ethanol. A health supplement for preventing or treating atopic dermatitis includes the extract of the organic solvent of the pine mushroom as the active ingredient. The pine mushroom extracts is obtained by the following steps: extracting the pine mushroom by using the polar solvent like ethanol water soluble solution, propanol, butanol, isopropanol, ethyl acetate, ether, acetone, chloroform and a mixed solvent thereof; easily obtaining by using a single or combining an adsorbent method like a Diaion HP-20 resin, dispersion of hexane and water, and a method using for separation extracting of plant components like column chromatography.
Abstract translation: 目的：提供一种用于预防或治疗特应性皮炎的组合物，其含有松果提取物，以减少作为蛋白质的细胞因子和TARC / CCL17，MDC / CCL22，CTACK / CCL27和ICAM-1的表达。 构成：用于预防或治疗特应性皮炎的组合物含有松果提取物作为活性成分。 有机溶剂为乙醇。 用于预防或治疗特应性皮炎的健康补充剂包括作为活性成分的松蘑的有机溶剂的提取物。 通过以下步骤获得松蘑菇提取物：使用极性溶剂如乙醇水溶液，丙醇，丁醇，异丙醇，乙酸乙酯，乙醚，丙酮，氯仿及其混合溶剂萃取松菇; 通过使用单一的或组合吸附剂方法如Diaion HP-20树脂，己烷和水的分散体以及用于分离提取植物组分如柱色谱法的方法容易地获得。
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公开(公告)号：KR101323150B1
公开(公告)日：2013-10-30
申请号：KR1020110038157
申请日：2011-04-25
Applicant: 충남대학교산학협력단
IPC: A61K31/12 , A61K31/045 , A61P19/10 , A61P19/00
Abstract: 본 발명은 잔토휴몰을 유효성분으로 하는 골다공증 예방 및 치료용 조성물에 관한 것으로 상기 잔토휴몰은 조골세포의 분화를 촉진하는 효과가 있어 골다공증을 비롯한 골질환의 치료에 효과적이다.
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