公开(公告)号：KR100414443B1

公开(公告)日：2004-01-07

申请号：KR1020000085129

申请日：2000-12-29

Applicant: 학교법인연세대학교

Inventor： 전철호 ,  이대연 ,  이혁 ,  홍준배

IPC: C07C45/29

Abstract: PURPOSE: Provided is a process for producing a ketone by reacting an aldehyde and an olefin, which improves the efficiency of a catalyst, therefore, it can improve yield and shorten the reaction time. CONSTITUTION: The ketone is produced by reacting an aliphatic or aromatic aldehyde and a vinyl olefin having an aliphatic or aromatic alkyl group in the presence of a transition metal catalyst, a 2-amino pyridine derivative, a primary amine, and an acid as a catalyst and additives, wherein the transition metal catalyst is at least one or two selected from the group consisting of a rhodium monovalent catalyst, a catalyst of the rhodium monovalent and a phosphine compound, a rhodium trivalent catalyst, a catalyst of the rhodium trivalent and the phosphine compound, a ruthenium catalyst, and an iridium catalyst.

Abstract translation: 目的：提供一种通过使醛和烯烃反应来制造酮的方法，其提高了催化剂的效率，因此可以提高收率并缩短反应时间。 构成：通过在过渡金属催化剂，2-氨基吡啶衍生物，伯胺和酸作为催化剂存在下使脂族或芳族醛与具有脂族或芳族烷基的乙烯基烯烃反应来制备酮 和添加剂，其中所述过渡金属催化剂为选自铑一价催化剂，铑一价催化剂和膦化合物中的至少一种或两种，三价铑催化剂，三价铑催化剂和膦 化合物，钌催化剂和铱催化剂。

公开(公告)号：KR1020020058129A

公开(公告)日：2002-07-12

申请号：KR1020000085128

申请日：2000-12-29

Applicant: 학교법인연세대학교

Inventor： 전철호 ,  홍준배 ,  정관용 ,  김연희

IPC: C07C49/00

Abstract: PURPOSE: Provided is an ortho-alkylation method of an aromatic ketone, which applies an alkyl group selectively to the ortho position of the aromatic ketone by reacting the aromatic ketone with an olefin. CONSTITUTION: The ortho-alkylation method is performed by (1) reacting the aromatic ketone with an alkyl contained compound, such as an aliphatic or aromatic alkyl contained olefin, an internal olefin, or a diene compound, in the presence of a primary amine and a transition metal catalyst or by (2) reacting the aromatic ketone with the primary amine to produce a ketimine and then reacting the ketimine with the alkyl contained compound in the presence of the transition metal catalyst.

Abstract translation: 目的：提供芳族酮的邻位烷基化方法，其通过使芳族酮与烯烃反应，将烷基选择性地施加到芳族酮的邻位。 构成：邻烷基化方法通过以下方法进行：（1）使芳族酮与含烷基的化合物如脂族或芳族烷基含有烯烃，内烯烃或二烯化合物在伯胺和 过渡金属催化剂或通过（2）使芳族酮与伯胺反应以产生酮亚胺，然后在过渡金属催化剂存在下使酮亚胺与含烷基的化合物反应。

公开(公告)号：KR100414442B1

公开(公告)日：2004-01-07

申请号：KR1020000085128

申请日：2000-12-29

Applicant: 학교법인연세대학교

Inventor： 전철호 ,  홍준배 ,  정관용 ,  김연희

IPC: C07C49/00

Abstract: PURPOSE: Provided is an ortho-alkylation method of an aromatic ketone, which applies an alkyl group selectively to the ortho position of the aromatic ketone by reacting the aromatic ketone with an olefin. CONSTITUTION: The ortho-alkylation method is performed by (1) reacting the aromatic ketone with an alkyl contained compound, such as an aliphatic or aromatic alkyl contained olefin, an internal olefin, or a diene compound, in the presence of a primary amine and a transition metal catalyst or by (2) reacting the aromatic ketone with the primary amine to produce a ketimine and then reacting the ketimine with the alkyl contained compound in the presence of the transition metal catalyst.

Abstract translation: 目的：提供芳族酮的邻烷基化方法，其通过使芳族酮与烯烃反应而选择性地将烷基施加到芳族酮的邻位。 构成：邻烷基化方法通过（1）在伯胺存在下，使芳族酮与含烷基的化合物如含脂族或芳族烷基的烯烃，内烯烃或二烯化合物反应，和 过渡金属催化剂或（2）使芳族酮与伯胺反应以产生酮亚胺，然后在过渡金属催化剂存在下使酮亚胺与含烷基的化合物反应。

公开(公告)号：KR1020020058130A

公开(公告)日：2002-07-12

申请号：KR1020000085129

申请日：2000-12-29

Applicant: 학교법인연세대학교

Inventor： 전철호 ,  이대연 ,  이혁 ,  홍준배

IPC: C07C45/29

Abstract: PURPOSE: Provided is a process for producing a ketone by reacting an aldehyde and an olefin, which improves the efficiency of a catalyst, therefore, it can improve yield and shorten the reaction time. CONSTITUTION: The ketone is produced by reacting an aliphatic or aromatic aldehyde and a vinyl olefin having an aliphatic or aromatic alkyl group in the presence of a transition metal catalyst, a 2-amino pyridine derivative, a primary amine, and an acid as a catalyst and additives, wherein the transition metal catalyst is at least one or two selected from the group consisting of a rhodium monovalent catalyst, a catalyst of the rhodium monovalent and a phosphine compound, a rhodium trivalent catalyst, a catalyst of the rhodium trivalent and the phosphine compound, a ruthenium catalyst, and an iridium catalyst.

Abstract translation: 目的：提供使醛和烯烃反应生成酮的方法，提高催化剂的效率，因此可以提高收率并缩短反应时间。 构成：通过在过渡金属催化剂，2-氨基吡啶衍生物，伯胺和酸作为催化剂的存在下使脂族或芳族醛与具有脂族或芳族烷基的乙烯基烯烃反应制备酮 和添加剂，其中所述过渡金属催化剂是选自铑单价催化剂，铑单价催化剂和膦化合物，铑三价催化剂，三价铑催化剂和膦的至少一种或两种 化合物，钌催化剂和铱催化剂。